Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ mTOR Inhibitor IV, Ku-63794
The mTOR Inhibitor IV, Ku-63794, also referenced under CAS 938440-64-3, controls the biological activity of mTOR. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ CL-387,785
A cell-permeable and irreversible inhibitor of EGF-receptor (EGFR) kinase activity
MilliporeSigma™ Calbiochem™ Lovastatin
Lovastatin, CAS 75330-75-5, is an anti-hypercholesterolemic agent that inhibits the activity of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase.
MilliporeSigma™ Calbiochem™ 2-APB
A cell-permeable modulator of Ins(1,4,5)P3-induced Ca2+ release.
MilliporeSigma™ Calbiochem™ Metformin
An antihyperglycemic agent that lowers blood glucose levels without stimulating insulin secretion, promoting weight gain or causing hypoglycemia.
MilliporeSigma™ Calbiochem™ β-Glucuronidase Inhibitor
The β-Glucuronidase Inhibitor controls the biological activity of β-Glucuronidase.
MilliporeSigma™ Calbiochem™ InSolution™ AG490
Potent inhibitor of epidermal growth factor receptor kinase autophosphorylation (IC50 = 100nM)
MilliporeSigma™ Calbiochem™ KN-92
KN-92, CAS 1135280-28-2, is useful as a negative control for KN-93 (Cat. No. 422708), a Ca2+/CaM Kinase II inhibitor.
MilliporeSigma™ Calbiochem™ Topoisomerase IIα Inhibitor, TSC24
The Topoisomerase IIα Inhibitor, TSC24 controls the biological activity of Topoisomerase. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ SUMOylation Inhibitor III, 2-D08
A cell-permeable compound that prevents the transfer of SUMO from the E2 thioester to the substrate without affecting SUMO-activating enzyme E1 (SAE-1/2) or E2 Ubc9-SUMO thioester formation.
MilliporeSigma™ Calbiochem™ Nitric Oxide Synthase, Neuronal Inhibitor I
The Nitric Oxide Synthase, Neuronal Inhibitor I, also referenced under CAS 357965-99-2, controls the biological activity of neuronal Nitric Oxide Synthase. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.
MilliporeSigma™ Calbiochem™ Autotaxin Inhibitor II, HA130
A thiazolidinedione that is designed to target the ATX active site thr210 with a boronic moiety and shown to potently inhibit ATX lysoPLD activity (IC50 ∽28nM using recombinant human ATX or human plasma) in a reversible manner with a mixed-type Lineweaver-Burk kinet
MilliporeSigma™ Calbiochem™ DNQX Disodium Salt
A potent competitive antagonist selective for AMPA/kainate glutamate receptors (IC50
MilliporeSigma™ Calbiochem™ BTS
A potent inhibitor of Ca2+-stimulated myosin S1 ATPase (IC50 = ≈5 μM) and reversibly blocks the gliding motility.
MilliporeSigma™ Calbiochem™ Neuronal Differentiation Inducer III
A cell-permeable isoxazole compound that selectively induces robust neuronal differentiation (Effective concentration = 20 μM) in various stem/progenitor cells.