Protein Purification Reagents and Kits
Supply Solutions Sigma Aldrich - Complete His-Tag Purific. Resin 200 Ml * Third Party Item
Sigma Aldrich - Complete His-Tag Purific. Resin 200 Ml * Third Party Item
AdipoGen IDO1 mouse rec His
Protein. Mouse IDO aa 1-407 is fused at the C-terminus to a His-tag. Source E. coli. Endotoxin content <1EU/µg purified protein LAL test Lonza. Liquid. 0.2µm-filtered solution in 50mM TRIS-Cl, pH 7.4, containing 1mM EDTA. Purity >90% SDS-PAGE. IDO catalyzes the first and rate-limiting step in the main pathway of human tryptophan catabolism, the kynurenine pathway. Proinflammatory mediators, such as endotoxin and IFN-gamma induce the expression of IDO in several tissues. IDO-dependent suppression of T cell responses might function as natural immunoregulatory mechanism. Physiological IDO activity has been implicated in T cell tolerance to tumors, dysfunctional selftolerance in non-obese diabetic NOD mice, and as a protective negative regulator in autoimmune disorders.
AdipoGen FGF-23 human rec His
Protein. Signal peptide and human FGF-23 aa 1-251 are fused at the C-terminus to a His-tag. Source HEK 293 cells. Endotoxin content <0.01EU/µg purified protein LAL test Lonza. Lyophilized. Contains PBS. Purity >90% SDS-PAGE. FGF-23 Fibroblast growth factor 23 is a regulator of phosphate homeostasis. It upregulates EGR1 expression in the presence of KLBy. Acts directly on the parathyroid to decrease PTH secretion. Regulates the vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization. Defects in FGF-23 are the cause of autosomal dominant hypophosphataemic rickets ADHR and of hyperphosphatemic familial tumoral calcinosis HFTC.
STEMCELL Technologies EasySepTM Human Monocyte Iso
Large-scale immunomagnetic isolation of untouched human monocytes - 1 x 10.10 cells
ABclonal Technology MonoMethyl-Histone H3-K9
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A H2B H3 and H4) The chromatin fiber is further compacted through the interaction of a linker histone H1 with the DNA between the nucleosomes to form higher order chromatin structures This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family Transcripts from this gene lack polyA tails instead they contain a palindromic termination element This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21 3
Abcam ATP-Agarose, 2ML
ATP-Agarose (ab270535) comprises ATP attached to agarose beads.
The product is subject to the following: Abcam Restricted Use Statement
AdipoGen PARP-1 h Hishigh purity
Protein. Human full-length PARP-1 ARTD1 is fused to a MYC and His-tag. Source Sf21 cells. Liquid. In 50mM TRIS-HCl, pH 7.5, containing 100mM sodium chloride and 50mM imidazole, 0.2% NP-40 and 10% glycerol. Purity >98% SDS-PAGE. PARP-1 ARTD1 is involved in the base excision repair BER pathway, by catalyzing the polyADP-ribosylation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. PARP-1 positively regulates the transcription of MTUS1 and negatively regulates the transcription of MTUS2/TIP150. It forms a complex with EEF1A1 and TXK that acts as a T-helper 1 Th1 cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production.
AdipoGen NAPRTase human rec His
Protein. Human NAPRTase is fused at the N-terminus to a His-tag. Source E. coli. Endotoxin content N/A. Liquid. In 50mM HEPES/KOH pH 7.5 containing 300mM potassium chloride and 10mM DTT. Purity >98% SDS-PAGE. Human nicotinate phosphoribosyltransferase NAPRTase is localized in the cytoplasm and is involved in biological processes such as NAD biosynthetic and metabolic processes, nicotinamide metabolic process, nicotinate nucleotide salvage, response to oxidative stress and water-soluble vitamin metabolic process. It functions by catalyzing the conversion of nicotinic acid NA to NA mononucleotide NaMN and is essential for NA to increase cellular NAD levels and prevent oxidative stress of the cells. It is a crucial factor in the NAD biosynthesis pathway. Catalytic activity Beta-nicotinate D-ribonucleotide diphosphate = nicotinate 5-phospho-alpha-D-ribose 1-diphosphate.
AdipoGen Calreticulin h rec His
Protein. Human calreticulin aa18-417 is fused at the C-terminus to a His-tag. Source E. coli. Endotoxin content <1EU/µg purified protein LAL test Lonza. Liquid. 0.2µm-filtered solution in 55mM TRIS-Cl, pH 8.2, containing 150mM NaCl. Purity >90% SDS-PAGE. Calreticulin is involved in regulation of intracellular Ca2 homoeostasis and ER Ca2 capacity. It constitutes together with calnexin and ERp57 the ‘calreticulin/calnexin cycle’ that is responsible for folding and quality control of newly synthesized glycoproteins. Calreticulin has been implicated to play a role in many biological systems, including functions inside and outside the ER, indicating that the protein is a multi-process molecule. Recently, Calreticulin was shown to enhance the merger of macrophages and tumor cells, increasing phagocytosis.
AdipoGen HES1 human rec His
Protein. Human HES1 aa 2-280 is fused at the N-terminus to a His-tag. Source E. coli. Liquid. 0.2µm-filtered solution in 55mM TRIS-Cl, pH 8.2, containing 150mM NaCl. Purity >90% SDS-PAGE. bHLH proteins are essential for neurogenesis, myogenesis, hematopoiesis and sex determination. HES1 Hairy and Enhancer of Split 1 is a basic Helix-Loop-Helix bHLH transcriptional repressor regulated by the Notch pathway and expressed in various tissues. HES1 is well known in development of different tissues, particularly endoderm derived endocrine organs like pancreas and neuroendocrine cells of lung. HES1 controls normal development by regulating proliferation and differentiation and so cell fate. Notch signaling plays both oncogenic and tumor suppressor roles depending on cell type. In contrast to T cell acute lymphoblastic leukemia ALL, where Notch activation promotes leukemogenesis, induction of Notch signaling in B cell ALL B-ALL leads to growth arrest and apoptosis.
AdipoGen PARP-1 E988K Mutant Ctrl
Protein. Human full-length inactive mutant E998K of PARP-1 is fused to a HA-tag and a His-tag. Source Sf21 cells. Liquid. In 50mM TRIS-HCl, pH 7.5, containing 100mM sodium chloride and 50mM imidazole, 0.2% NP-40 and 10% glycerol. Purity >95% SDS-PAGE. PARP-1 ARTD1 is involved in the base excision repair BER pathway, by catalyzing the polyADP-ribosylation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. PARP-1 positively regulates the transcription of MTUS1 and negatively regulates the transcription of MTUS2/TIP150. It forms a complex with EEF1A1 and TXK that acts as a T-helper 1 Th1 cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production.
AdipoGen TDO Anopheles gambiaeHis
Protein. Full-length TDO Anopheles gambiae is fused at the N-terminus to a His-tag. Source E. coli. Endotoxin content N/A. Liquid. In 50mM sodium phosphate pH 8.0, containing 0.15M sodium chloride, 0.2M imidazole and 10% glycerol. Purity >98% SDS-PAGE. Tryptophan 2,3-dioxygenase TDO is a heme-containing dioxygenase catalyzing the addition of molecular oxygen across the 2,3-double bond of the indole ring of tryptophan to form N-formylkynurenine NFK. In Anopheles gambiae, TDO is the only enzyme able to catalyze the first and rate-limiting step in L-Trp catabolism through the kynurenine pathway. Tryptophan is an essential amino acid for protein synthesis and also the precursor for production of a number of neurotransmitters, such as serotonin and melatonin in mosquitoes, the kynurenine pathway is essential for eye pigmentation.
American Research Products Inc AMERICAN RESEARCH PRODUCTS INC
5000603200 AMY2/AMYLASE ALPHA 2 ELISA KIT