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Filtered Search Results
Cayman Chemical AmIdepsIn D 2.5mg
A fungal metabolite that inhibits DGAT activity, preventing triacylglycerol formation (IC50s = 17.5 and 2.8 µM in rat liver microsomes and Raji cells, respectively)
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OriGene SLC7A6 (NM_003983) Human Tagged ORF Clone Lentiviral Particle, 200ul
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Lenti ORF particles, SLC7A6 (Myc-DDK tagged) - Human solute carrier family 7 (cationic amino acid transporter, y+ system), member 6 (SLC7A6), transcript variant 1, 200ul, >10^7 TU/mL
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ABclonal Technology ACSL1 Rabbit pAb
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The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. Several transcript variants encoding different isoforms have been found for this gene.
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Abcam Human RPL36AL knockout HEK-293T cell lysate.
Human RPL36AL knockout HEK-293T cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
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Abcam HeLa DNA Damage Whole Cell Lysate Set: UV Treated and Untreated Control, 2UNIT
UV light is a common source of DNA damage, and can lead to skin cancer and premature aging.
The product is subject to the following: Abcam Restricted Use Statement
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ABclonal Technology TRAF3 Rabbit pAb
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The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. The protein also plays a role in the regulation of antiviral response. Mutations in this are associated with Encephalopathy, acute, infection-induced, herpes-specific 5.
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ABclonal Technology XRCC4 Rabbit pAb
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The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. This protein plays a role in both non-homologous end joining and the completion of V(D)J recombination. Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED). Alternate transcript variants such as NM_022406 are unlikely to be expressed in some individuals due to a polymorphism (rs1805377) in the last splice acceptor site.
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Cayman Chemical ntImycIn A4 2.5mg
A component of the antimycin A complex and an inhibitor of ATP-citrate lyase (Ki = 64.8 µM)
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ABclonal Technology PE anti-Human CD171/L1CAM
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The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family The ectodomain consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III) is linked via a single transmembrane sequence to a conserved cytoplasmic domain This cell adhesion molecule plays an important role in nervous system development including neuronal migration and differentiation Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia retardation aphasia spastic paraplegia and hydrocephalus) Alternative splicing of this gene results in multiple transcript variants some of which include an alternate exon that is considered to be specific to neurons
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Abcam Human COL4A6 (Collagen IV alpha 6) knockout HeLa cell lysate.
Human COL4A6 (Collagen IV alpha 6) knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
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Abcam Human PQBP1 knockout HEK-293T cell lysate.
Human PQBP1 knockout HEK-293T cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
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Rockland Immunochemicals MDA-MB-231 Whole Cell Lysate - W09-001-GK6
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Multi-purpose MDA-MB-231 Whole Cell Lysates produced by Rockland Immunochemicals are derived from cell lines using highly refined extraction protocols to ensure exceptionally high quality, protein integrity and lot-to-lot reproducibility. All extracts are tested by SDS-PAGE using 4-20% gradient gels.
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Abcam Human SYNJ2 (Synaptojanin 2) knockout HeLa cell lysate.
Human SYNJ2 (Synaptojanin 2) knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
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ABclonal Technology PTPN1 Rabbit pAb
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The protein encoded by this gene is the founding member of the protein tyrosine phosphatase (PTP) family, which catalyzes the hydrolysis of phosphate monoesters on tyrosine residues. PTPs are key signaling molecules that regulate cellular processes such as growth, differentiation, the cell cycle, and oncogenic transformation. This PTP acts as a negative regulator of insulin signaling by dephosphorylating the insulin receptor kinase. It also dephosphorylates epidermal growth factor receptor kinase, JAK2, and TYK2 kinases, implicating it in cell growth control and responses to interferon. Two transcript variants encoding different isoforms have been identified for this gene.
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Cayman Chemical 7DeazaadenosIn5OtrIphos 2.5mg
A modified nucleotide and an active metabolite of tubercidin; incorporated into the DNA of mouse L-cells using DNA polymerase α but not into the RNA of E. coli using RdRps; has been used as a probe for the ATP binding site of PKA
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