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Abcam Lomeguatrib, MGMT inhibitor, 25MG
MW 326.17 Da, Purity >98%. Potent O⁶-methylguanine-DNA methyltransferase (MGMT) inhibitor (IC₅₀ = 9 nM). Inhibits recombinant human ATase (IC₅₀ = 5 nM). Shows antitumor effects in vivo. Enhances antitumor effects of temozolomide (ab141055).
The product is subject to the following: Abcam Restricted Use Statement
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Cayman Chemical C16 dIhydro CeramIded18 01 1mg
A precursor in the de novo synthesis of C16 ceramide; inhibits C16 ceramide-induced membrane permeabilization in rat liver mitochondria and channel formation in liposomes; biologically inactive as a single agent
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