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DSPC (1,2-distearoyl-sn-glycero-3-phosphorylcholine) is a cylindrical-shaped phospholipid used to form liposomes and as a structural lipid in lipid nanoparticle (LNP) systems. It is supplied for research use and is commonly employed in membrane model studies and formulation development.
Cylindrical phospholipid suitable for liposome and LNP formulations.
High purity (99.95%).
Molecular formula C44H88NO8P; molecular weight 790.15 g/mol.
Common pack sizes include 100 mg, 500 mg, 1 g, 5 g, 10 g, and 50 g.
For research use only; not for use in patients.
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PEG2000-C-DMG is a pegylated lipid used in the preparation of an investigational RNAi therapeutic agent. This agent works by targeting the 3′ untranslated region of transthyretin mRNA, reducing the production of mutant and wild-type transthyretin.
Used in the preparation of an investigational RNAi therapeutic agent
Targets the 3′ untranslated region of transthyretin mRNA
Reduces production of mutant and wild-type transthyretin
Intended for research use only
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DSPE-PEG2000-GE11 is a nanocarrier component composed of DSPE and the EGFR-targeting peptide (GE11). It specifically binds to EGFR, mediating receptor-mediated endocytosis of micellar drug carriers for drug delivery.
Specifically binds to EGFR.
Mediates receptor-mediated endocytosis of micellar drug carriers.
Enhances EGFR-dependent cellular uptake of doxorubicin (1.4-fold higher in SMMC-7721 cells).
Inhibits HUVEC proliferation, induces G2-M phase arrest, reduces cell migration, and alters HUVEC morphology when modified.
Enhances tumor accumulation of DiR-loaded micelles in EGFR-positive hepatocellular carcinoma xenografts.
Confers EGFR-targeted accumulation to liposomal formulations in liver cancer xenografts.
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DSPE-PEG2000-PDP is a phospholipid PEG conjugate utilized in drug delivery applications. It has a molecular weight of 2000 (average) and a CAS number of 474922-24-2. The product appears as a solid with a white to off-white color. It boasts a purity of 90.0%.
Molecular weight of 2000 (average)
Solid appearance with a white to off-white color
Purity of 90.0%
Utilized in drug delivery applications
Functions as a phospholipid PEG conjugate
Can act as an inhibitor
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C18:1 Glucosyl(ß) Ceramide (d18:1/18:1(9Z)) is a high-purity glycosphingolipid from Avanti Polar Lipids. This ceramide consists of an oleoyl fatty acid chain and a D-erythro-sphingosine base, and is available in a 5 mg quantity. The empirical formula is C42H79NO8, with a molecular weight of 726.079, making it valuable for lipid biology research.
High-purity glycosphingolipid
Available in 5 mg quantity
Empirical formula: C42H79NO8
Molecular weight: 726.079
Lipid class: Glycosphingolipid, Ceramide
Fatty acid: 9Z-octadecenoyl (Oleoyl)
Sphingoid base: D-erythro-sphingosine (d18:1)
Physical form: Powder
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1-Palmitoyl-sn-glycero-3-phosphocholine-d49 is the deuterium-labeled isotopologue of 1-palmitoyl-sn-glycero-3-phosphocholine (16:0 Lyso PC). Supplied as a solid, it is used as an analytical reference and internal standard in lipidomics and mass spectrometry workflows to enable accurate quantitation of lysophosphatidylcholine species.
Isotopically labeled with 49 deuterium atoms (d49).
Chemical formula C24HD49NO7P.
Molecular weight 544.93.
CAS number 2315262-40-7.
Supplied as a solid in small pack sizes, suitable for analytical use.
Intended for use as an internal standard in LC-MS/MS and lipid analysis.
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DSPE-PEG2000-PDP is a PEGylated phospholipid bearing a pyridyldithio (PDP) functional group that enables thiol-reactive conjugation. It is used to introduce thiol-reactive handles into liposomes and lipid nanoparticles, providing PEG-based steric stabilization and a route for disulfide-mediated ligand attachment. Typical research applications include nanoparticle surface modification and targeted drug delivery.
Enables thiol-reactive conjugation via pyridyldithio disulfide exchange.
PEG2000 chain provides steric stabilization and reduced opsonization.
Suitable for liposome and lipid nanoparticle surface modification.
Allows attachment of thiol-containing ligands such as peptides or antibodies.
Facilitates controlled surface density of functional groups.
Available in small research pack sizes for formulation development.
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An ionizable cationic lipid; has been used in the formation of LNPs; LNPs containing DLin-MC2-DMA and encapsulating siRNA targeting mRNA encoding FVII reduce hepatic levels of FVII in mice (ED50 = 0.6 mg/kg)
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