Choose the brand aligned with your industry so we can best serve your needs.
For researchers, scientists, and technical professionals: Your one-stop shop for the complete range of laboratory, production, and safety products and services.
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
DSPE-PEG2000-cRGD is a polyethylene glycol-lipid conjugate that links DSPE to a PEG2000 spacer terminated with a cyclic RGD peptide targeting αvβ3 integrins. Supplied as a white to off-white solid for research use, it is intended for incorporation into lipid nanoparticles and other targeted delivery systems to enhance tumor and neovasculature binding.
Provides αvβ3-targeting through a cRGD ligand.
Facilitates surface functionalization of lipid nanoparticles.
PEG2000 spacer improves circulation and steric stability.
Supplied as a solid with reported purity of ~96.2%.
Stable under frozen storage; follow supplier storage instructions.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
DSPE-PEG2000-NH2 (CAS 474922-26-4) is an amphiphilic polymer conjugate composed of 1 2-distearoyl-sn-glycero-3-phosphoethanolamine (DSPE) and polyethylene glycol (PEG MW 2000 Da) terminating in a primary amine The compound is designed for covalent coupling to biomolecules through its amine functional group enabling surface modification of lipid-based nanoparticles including liposomes and lipid nanoparticles DSPE-PEG2000-NH2 acts primarily by enabling conjugation of peptides proteins antibodies or nucleic acids to nanoparticle surfaces via stable amide bond formation with accessible carboxyl groups Based on these characteristics DSPE-PEG2000-NH2 holds research potential in targeted drug delivery nucleic acid delivery and nanoparticle surface modification in biomedical and pharmaceutical applications
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
DLin-KC2-DMA is an ionizable cationic lipid used to formulate lipid nanoparticles (LNPs) for siRNA and nucleic acid delivery. It has an apparent pKa near 6-6.7 and has been reported to enable significant siRNA-mediated gene silencing while exhibiting low toxicity to antigen-presenting cells.
Ionizable cationic lipid with apparent pKa ≈ 6-6.7.
Facilitates efficient encapsulation and delivery of siRNA in lipid nanoparticles.
Produces significant siRNA-mediated gene silencing in LNP formulations.
Low toxicity to antigen-presenting cells, suitable for biological studies.
High-purity liquid, colorless to light yellow; compatible with formulation workflows.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
DMG-PEG2000-N3 is a PEGylated lipid derivative utilized for the functionalization of lipid-based drug delivery systems It consists of 1 2-dimyristoyl-sn-glycerol (DMG) polyethylene glycol (PEG 2000 Da) and a terminal azide group (N3) The azide functional group enables selective conjugation via copper-catalyzed azide-alkyne cycloaddition (CuAAC or click chemistry) allowing controlled attachment of biomolecules small-molecule drugs fluorescent probes or targeting ligands onto lipid bilayers DMG-PEG2000-N3 is widely applied in the development of liposomal or nanoparticle formulations for targeted drug delivery and imaging in biomedical research
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
8-Dehydrocholesterol is an endogenous cholesterol precursor whose elevated concentration is a diagnostic biochemical hallmark of classical Smith-Lemli-Opitz syndrome (SLOS). Supplied as a solid reference standard for research and analytical applications, it is characterized by documented chemical identifiers and supporting documentation for laboratory use.
CAS number 70741-38-7.
Purity 93.63% (analytical).
Molecular formula C27H44O; molecular weight 384.64 g·mol⁻¹.
Soluble in DMSO (5.56 mg/mL); ultrasonic warming to 60°C may improve solubility.
Store solid at -20°C, protect from light, and maintain under nitrogen; in solution store at -80°C up to 6 months.
Certificate of analysis and safety data sheet available for download.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
The melanocortin receptor 3 MC3 receptor is Gs-coupled GPCRs expressed in brain placental and gut tissues but not in melanoma cells or in the adrenal gland MC3 receptor knockouts exhibit a metabolic syndrome At 4-6 months old MC3 receptor knockout mice show increased fat mass reduced lean mass and a higher feed efficiency with normal metabolic rates MC3 receptor knockout mice are hyperleptinaemic and males are often mildly hyperinsulinaemic
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More