Substrates
Cayman Chemical Boc-Lys Ac-AMC 10mg
A fluorogenic HDAC substrate; ex/em = 340-360/440-460 nm, respectively; following deacetylation by an HDAC and trypsin cleavage, AMC is released and its fluorescence can be used to quantify HDAC activity
Echelon Biosciences Research Labs Autotaxin Inhibitor Screening Kit
The Autotaxin Inhibitor Screening Kit utilizes purified autotaxin (ATX) and the autotaxin substrate FS-3, which fluoresces upon cleavage. The assay is performed in a 96 well plate and quantifies the autotaxin activity in the presence of the users samples by measuring changes in fluorescence over time.Sample Type: Inhibitors against ATXSample Volume: 10 L/ well of your sample compoundsSample Considerations: Some organic solvents interfere with the assay (see technical data sheet). This item is non returnable
CPC Scientific DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS (trifluoroacetate salt) 1MG
Useful FRET substrate for a continuous fluorescence-based assay of the malaria aspartyl protease (plasmepsin). The peptide sequence ERNleFLSFP is derived from the cleavage site present in hemoglobin, with Nle as a substitution for Met to avoid potential oxidation related problems.SEQUENCE: DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS (trifluoroacetate salt)ONE-LETTER SEQUENCE: ERNleFLSFPMOLECULAR FORMULA: C76H98N16O15S1MOLECULAR WEIGHT: 1507.78STORAGE CONDITIONS: -20 5 CCAS REGISTRY NUMBER: [263718-22-5]SYNONYMS: RESEARCH AREA: AntimicrobialREFERENCES:M.Pennington et al., Innovation and Perspectives in Solid Phase Synthesis & Combinatorial Libraries, 5th International Symposium, London, p. 367, R.Epton, ed., Mayflower Scientific, (1998)S.Jiang et al., Antimicrob. Agents Chemother., 45, 2577 (2001)M.Stadler et al., J. Antibiot., 58, 775 (2005)SKU(s): MALA-001A, MALA-001B
Medchemexpress LLC Boc-Leu-Gly-Arg-AMC | 65147-09-3 | 98.3% | 601.69 | 5 MG
Boc-Leu-Gly-Arg-AMC is a fluorogenic AMC substrate primarily used for convertases. This compound is suitable for use in enzymatic assays. Research has shown its application in developing enzymatic assays to detect proteolytic enzymes, such as those capable of generating sodefrin, by measuring the liberation of 7-amino-4-methylcoumarin. The optimal activity for cleaving Boc-Leu-Gly-Arg-AMC in certain extracts has been observed at pH 9.0 and 45 °C.
- Fluorogenic AMC substrate for convertases.
- Can be used in enzymatic assays.
- Suitable for demonstrating the presence of proteolytic enzymes.
Revvity Health Sciences Inc LANCE Ultra Human IRS1 Ulight Peptide Substrate, 10 nmoles
LANCE Ultra Human IRS1 Ulight Peptide Substrate, 10 nmoles
Revvity Health Sciences Inc LANCE Ultra IκBα Ulight Peptide Substrate, 5 nmoles
LANCE Ultra IκBα Ulight Peptide Substrate, 5 nmoles
Research Products International Corp 1-Naphthyl Phosphate Monosodium Salt Monohydrate, 25 Grams
Substrate for determaination of phosphatase. Protect from moisture.
Enzo Life Sciences FLUOR DE LYS SIRT2 deacetylase substrate (0.5µmol)
FLUOR DE LYS-SIRT2 is a fluorogenic peptide substrate for SIRT2 (human Sirtuin 2). Based on residues 317-320 of p53 (Gln-Pro-Lys-Lys(Ac)), a site of regulatory acetylation by the PCAF acetyltransferase (lysine 320), it was the best for SIRT2 from among a panel of substrates patterned on p53, Histone H3, and Histone H4 acetylation sites. FLUOR DE LYS-SIRT2 deacetylase substrate is deacetylated by SIRT2 at a rate of more than 50-fold that of the acetylated lysine substrate (BML-KI104; acetylated substrates both at 25 µM, 500 µM NAD+). Must be used in conjunction with FLUOR DE LYS Developer II (BML-KI176). Sufficient for 100 assays of human recombinant SIRT2 (BML-SE251; 2U/well, 100 µM substrate). Purity: ≥95% (HPLC). Formulation: Supplied as a 5mM solution (100 µl) in HDAC Assay Buffer. Long Term Storage: -80°C.
eMolecules 147808-41-1 | 3,5-DIFLUORO-4-NITROPHENOL | MFCD15527692 | 0.25g
Medchem Express | PPOH | 5mg | 783660405 | HY-119647 | 206052-01-9 | MFCD03453622 | 246.306 | C15H18O3
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STA PHARMACEUTICAL US LLC Fmoc-D-2-Nitrophe | 25 g | CAS 478183-70-9 | MDL MFCD01317714
Fmoc-D-2-Nitrophe is a Amino Acid reagent (Subcategory: Phe) sold by WuXi TIDES. Offered in 25 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 478183-70-9
- MDL: MFCD01317714
- InChIKey: KVLRWXBYPKSBFY-OAQYLSRUSA-N
- Molecular Weight: 432.432
- Molecular Formula: C24H20N2O6
- Purity: ≥95%
- Container Type: 125 mL HDPE
- Pack Size: 25 g
- Net Weight: 25 g
- Gross Weight: 54.3 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: (R)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(2-nitrophenyl)propanoic acid
- SMILES: O=C([C@@H](CC1=CC=CC=C1[N+]([O-])=O)NC(OCC2C3=CC=CC=C3C4=CC=CC=C42)=O)O
Cayman Chemical Gly-Gly-AMC 1mg
A fluorogenic peptide substrate; used to assess the activity of bacterial proteases from P. aeruginosa and S. aureus; enzyme activity can be quantified by fluorescent detection of free AMC (also known as 7-amino-4-methylcoumarin), which is excited at 340-360 nm and emits at 440-460 nm
Medchemexpress LLC Boc-Gly-Lys-Arg-AMC | 109358-48-7 | 616.71 | 25 MG
Boc-Gly-Lys-Arg-AMC is a polypeptide identified through peptide screening, a research tool that primarily uses immunoassay to pool active peptides. This method is applicable for protein interaction, functional analysis, and epitope screening, particularly in agent research and development.
- Identified through peptide screening
- Utilizes immunoassay to pool active peptides
- Applicable for protein interaction studies
- Suitable for functional analysis
- Useful for epitope screening
- Valuable in agent research and development
- For research use only
Medchemexpress LLC Ac-YEVD-AMC | 1631716-11-4 | 99.6% | 723.73 | 5 MG
Ac-YEVD-AMC is a fluorescent substrate of caspase-1/11 that releases amino-4-methylcoumarin (AMC) for fluorescence detection when treated with cell lysate. This product is for research use only.
- Fluorescent substrate of caspase-1/11
- Releases amino-4-methylcoumarin (AMC) for fluorescence detection
- For research use only
CPC Scientific H-Asp-Arg-Val-Tyr-Ile-His-Pro-Val-His-Leu-Leu-Tyr-Tyr-Ser-OH (trifluoroacetate salt) 1MG
ONE-LETTER SEQUENCE: DRVYIHPVHLLYYSMOLECULAR FORMULA: C85H123N21O21MOLECULAR WEIGHT:1775.1STORAGE CONDITIONS: -20 5CRESEARCH AREA: Cardiovascular
Medchemexpress LLC 6′-amino-D-luciferin | 161055-47-6 | MFCD29912852 | ≥95.0% | 279.34 g/mol | C11H9N3O2S2 | 5 MG
6′-Amino-D-luciferin is a derivative of D-luciferin with the 6-position hydroxyl replaced by an amino group. It acts as a luciferase substrate for bioluminescence assays and is commonly used for IVIS imaging in cell and animal studies. The compound is supplied as a solid with defined storage recommendations and standard analytical characterization for laboratory use.
- Natural substrate for luciferase enabling bioluminescent assays.
- Suitable for IVIS imaging in cell and animal experiments.
- Solid, light yellow to brown appearance for easy handling.
- Stable under recommended cold storage conditions for long-term use.
- Molecular weight 279.34 g/mol and CAS 161055-47-6 for identification.