Isotopically Labeled Compounds
Medchemexpress LLC Camptothecin-d5 | 1329616-37-6 | 99.6% | 353.38 | 1 MG
Camptothecin-d5 is the deuterium labeled Camptothecin. Camptothecin (CPT), a kind of alkaloid, is a DNA topoisomerase I (Topo I) inhibitor with an IC50 of 679 nM. Camptothecin (CPT) exhibits powerful antineoplastic activity against colorectal, breast, lung and ovarian cancers, modulates hypoxia-inducible factor-1α (HIF-1α) activity by changing microRNAs (miRNA) expression patterns in human cancer cells.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Colchicine-d3 | 1217625-62-1 | 99.2% | 402.46 | 1 MG
Colchicine-d3 is the deuterium labeled Colchicine. It acts as a tubulin inhibitor and a microtubule disrupting agent, effectively inhibiting microtubule polymerization with an IC50 of 3 nM. This compound also functions as a competitive antagonist of the α3 glycine receptors (GlyRs).
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Inhibits microtubule polymerization
- Competitive antagonist of α3 glycine receptors
Medchemexpress LLC Vericiguat-d3 hydrochloride | 1350653-20-1 | 99.8% | 465.86 | 1 MG
Vericiguat-d3 (BAY1021189-d3) hydrochloride is a deuterated Vericiguat with tracer functionality. Vericiguat is an orally available stimulator of guanylate cyclase.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Vericiguat-d3 hydrochloride | 1350653-20-1 | 99.8% | 465.86 | 5 MG
Vericiguat-d3 hydrochloride is a deuterated Vericiguat with tracer functionality. Vericiguat is an orally available stimulator of guanylate cyclase. This compound can be used as a tracer or as an internal standard for quantitative analysis.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Apalutamide-13C,d3 | 956104-40-8 | 99.9% | 481.45 | 1 MG
Apalutamide-13C,d3 is a 13C- and deuterium labeled form of Apalutamide (ARN-509), a potent and competitive androgen receptor (AR) antagonist. This compound incorporates stable heavy isotopes of hydrogen, carbon, and other elements, making it suitable for quantitative analysis during drug development processes. Deuteration has also garnered attention for its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Potent and competitive androgen receptor (AR) antagonist.
- Binds AR with an IC50 of 16 nM.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Apalutamide-d4 | 1638885-65-0 | 99.9% | 481.46 | 5 MG
Apalutamide-d4 is a deuterium labeled Apalutamide. Apalutamide is a potent and competitive androgen receptor (AR) antagonist, binding AR with an IC50 of 16 nM.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Maribavir-d6 TFA | 176161-24-3 | 496.30 | 1 MG
Maribavir-d6 TFA is a deuterium-labeled Maribavir, an orally active antiviral agent. It targets cytomegalovirus (CMV) by inhibiting protein kinase UL97, thereby preventing CMV DNA replication. This compound is suitable for various analytical techniques.
- Used as a tracer.
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Apalutamide-13C,d3 | 956104-40-8 | 99.9% | 481.45 | 500 UG
Apalutamide-13C,d3 is a 13C- and deuterium labeled Apalutamide, which is a potent and competitive androgen receptor antagonist. It is intended for research use only and serves as a valuable tool for quantitative analysis in drug development.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Incorporated stable heavy isotopes of hydrogen, carbon, and other elements into drug molecules for quantitation
- Deuteration can potentially affect the pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC D-glucose-13C2 | 201741-04-0 | 98.0% | 25 MG
D-Glucose-13C2 is the 13C labeled D-Glucose, a monosaccharide and important carbohydrate in biology. It serves as a carbohydrate sweetener and a critical component of general metabolism, acting as a signaling molecule in relation to both cellular metabolic status and biotic and abiotic stress response.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC D-Glucose-13C-4 | 40762-22-9 | 98.0% | 25 MG
D-Glucose-13C-4 is a 13C labeled D-Glucose, a monosaccharide and an important carbohydrate in biology. It serves as a critical signaling molecule related to cellular metabolic status and stress response. This compound is suitable for use as a tracer and internal standard in quantitative analyses such as NMR, GC-MS, or LC-MS.
- 13C labeled D-Glucose
- Important carbohydrate in biology
- Carbohydrate sweetener
- Critical component of general metabolism
- Critical signaling molecule in relation to cellular metabolic status and stress response
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC D-Glucose-13C2-4 | 138079-87-5 | 98.0% | 25 MG
D-Glucose-13C2-4 is the 13C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. It is a carbohydrate sweetener and a critical component of general metabolism, serving as a critical signaling molecule in relation to both cellular metabolic status and biotic and abiotic stress response.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes have been incorporated into drug molecules for quantitation during drug development.
- Deuteration has potential to affect pharmacokinetic and metabolic profiles of drugs.
