Isotopically Labeled Compounds
![Medchemexpress LLC 1-Naphthalenesulfonyl chloride, 5-[di(methyl-d3)amino]- | 1276379-68-0 | 98.0% | 1 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000410136-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 1-Naphthalenesulfonyl chloride, 5-[di(methyl-d3)amino]- | 1276379-68-0 | 98.0% | 1 MG
Dansyl chloride-d6 is the deuterium labeled form of Dansyl chloride, a reagent known for producing stable blue or blue-green fluorescent sulfonamide adducts. It reacts with aliphatic and aromatic amines containing primary amino groups and is widely utilized for modified amino acids, protein sequencing, and amino acid analysis. This compound serves as a valuable tracer and an internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS.
- Can be used as a tracer
- Functions as an internal standard for quantitative analysis
- Applicable in NMR, GC-MS, or LC-MS
- Deuterium-labeled compound
Medchemexpress LLC Stearic acid-d2 | 19905-58-9 | 99.1% | 100 MG
Stearic acid-d2 is the deuterium labeled Stearic acid, a long chain dietary saturated fatty acid found in animal and vegetable fats and oils. This compound can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Used as a tracer for various applications
- Serves as an internal standard for quantitative analysis
- Deuterium substitution can affect pharmacokinetic and metabolic profiles
Cayman Chemical Chlorzoxazone-d3, Purity: ≥99% deuterated forms (d1-d3), CAS: 1185173-60-7, 1 mg
An internal standard for the quantification of chlorzoxazone by GC- or LC-MS
Cambridge Isotope Laboratories 3-NITRO-L-TYROSINE (RING-13C6, 99%) 94%+ PURE, 0.01 G
3-NITRO-L-TYROSINE (RING-13C6, 99%) 94%+ PURE, 0.01 G
Medchemexpress LLC Sulfanilamide-d4 | 77435-46-2 | 99.99% | 1 MG
Sulfanilamide-d4 is the deuterium labeled Sulfanilamide. It acts as a competitive inhibitor for the bacterial enzyme dihydropteroate synthetase, with an IC50 of 320 μM. Stable heavy isotopes of elements such as hydrogen, carbon, and others have been integrated into drug molecules to serve as tracers for quantitation during drug development. Deuteration is also noted for its potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Deuterium labeled compound
- Competitive inhibitor for bacterial enzyme dihydropteroate synthetase
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stable heavy isotopes serve as tracers for quantitation
- Potential to influence pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Niacin-d4 | 66148-15-0 | 99.7% | 5 MG
Niacin-d4 is the deuterium labeled Niacin, a vitamin and part of the vitamin B group. It is intended for research use only.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Cambridge Isotope Laboratories PHENOL (13C6, 99%), 0.1 G, 89059-34-7
PHENOL (13C6, 99%), 0.1 G, 89059-34-7
Cayman Chemical Stearic Acid-d4, Purity: ≥99% deuterated forms (d1-d4), CAS: 130048-57-6, 10 mg
An internal standard for the quantification of stearicacid by GC- or LC-MS
Medchemexpress LLC Hydrocortisone-d2 | 1257650-73-9 | 364.47 | 1 MG
Hydrocortisone-d2 is the deuterium labeled Hydrocortisone. Hydrocortisone (Cortisol) is a steroid hormone or glucocorticoid secreted by the adrenal cortex. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Cambridge Isotope Laboratories Lauryl-N N-dimethylamine-N-oxide (LDAO) (lauryl-D25 dimethylamine-D6 97%) 0 1 g
Lauryl-N N-dimethylamine-N-oxide (LDAO) (lauryl-D25 dimethylamine-D6 97%) 0 1 g
Medchemexpress LLC L-serine-13C3,15N | 202407-34-9 | MFCD00144678 | 99.9% | 109.06 | 13C3H7 15NO3 | 10 MG
L-Serine-13C3,15N is a stable isotope-labeled L-serine in solid form, with three 13C atoms and one 15N atom. It is supplied as a high-purity analytical standard for mass spectrometry, metabolic tracing, and biochemical assays.
- Stable isotope-labeled reference standard for MS and tracer studies.
- Isotopic enrichment: three 13C atoms and one 15N atom.
- High purity (99.9%) suitable for quantitative analysis.
- Molecular weight 109.06 and CAS number 202407-34-9 for unambiguous identification.
- Physical form: solid powder; soluble in water.
- Typical applications include internal standard, metabolic flux analysis, and pathway tracing.
Medchemexpress LLC L-HOMOCYSTINE-D8 | 182755-41-5 | 99.9% | 276.40 | 1 MG
L-Homocystine-d8 is the deuterium labeled L-Homocystine. L-Homocystine is the oxidized member of L-homocysteine, which is a pro-thrombotic factor, vasodilation impairing agent, pro-inflammatory factor, and endoplasmatic reticulum-stress inducer. It is used to study cardiovascular disease mechanisms.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes incorporated into drug molecules for quantitation during drug development.
- Deuteration has the potential to affect pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC L-Asparagine-15N2 monohydrate | 287484-32-6 | 152.12 | 5 MG
L-Asparagine-15N2 monohydrate is the 15N-labeled version of L-Asparagine monohydrate. L-Asparagine monohydrate is an essential amino acid for leukemic cells and serves as a substrate for L-Asparaginase. L-Asparaginase is a potent anti-leukemic enzyme that depletes asparagine (Asn) and glutamine (Gln), thereby inhibiting protein biosynthesis in lymphoblasts. The removal of L-asparagine from plasma by L-Asparaginase leads to inhibition of RNA and DNA synthesis and subsequent apoptosis. L-Asparaginase demonstrates cell-killing ability both in vitro and in vivo, selectively inhibiting the growth of cancer cells that have low asparagine synthetase (AASNS) expression. L-Asparagine monohydrate can also be utilized as a biomarker and sensor for the study of childhood acute lymphoblastic leukemia.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Cayman Chemical Dabigatran-13C-d3, Purity: ≥99% deuterated forms (d1-d3), CAS: 2967480-55-1, 1 mg
An internal standard for the quantification of dabigatran by GC- or LC-MS
Medchemexpress LLC Cinnamic acid-13C3 (3-Phenylacrylic acid-13C3) | 2734410-01-4 | 151.14 | 100 UG
Cinnamic acid-13C3 (3-Phenylacrylic acid-13C3) is the 13C labeled Cinnamic acid, which has potential use in cancer intervention, with IC50s of 1-4.5 mM in glioblastoma, melanoma, prostate and lung carcinoma cells. It incorporates stable heavy isotopes for quantitation during drug development.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes have been incorporated into drug molecules for quantitation during the drug development process.
- Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.