Isotopically Labeled Compounds
Medchemexpress LLC Spermidine-d6 | 2514812-10-1 | 96.1% | 5 MG
Spermidine-d6 is the deuterium labeled Spermidine, designed for research applications. It plays a role in maintaining cell membrane stability, increasing antioxidant enzyme activities, and improving photosystem II (PSII) and relevant gene expression. This compound significantly decreases H2O2 and O2.- contents. Deuteration, incorporating stable heavy isotopes into drug molecules, has gained attention for its potential to affect pharmacokinetic and metabolic profiles of drugs, making Spermidine-d6 valuable as a tracer and internal standard.
- Used as a tracer
- Internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Maintains cell membrane stability
- Increases antioxidant enzyme activities
- Improves photosystem II (PSII) and relevant gene expression
- Decreases H2O2 and O2.- contents
Medchemexpress LLC Tamoxifen-d5 | 157698-32-3 | 99.99% | 376.55 | 1 MG
Tamoxifen-d5 is a deuterium labeled Tamoxifen. Tamoxifen (ICI 47699) is an orally active, selective estrogen receptor modulator (SERM). It is a potent Hsp90 activator and enhances Hsp90 molecular chaperone ATPase activity. Deuteration of drug molecules has gained attention for its potential to affect pharmacokinetic and metabolic profiles.
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Incorporates stable heavy isotopes for quantitation
Medchemexpress LLC Methyl nicotinate-d4 | 345909-99-1 | 99.5% | 5 MG
Methyl nicotinate-d4 is the deuterium labeled Methyl nicotinate, used as an active ingredient as a rubefacient in over-the-counter topical preparations for muscle and joint pain. This compound can be used as a tracer and as an internal standard for quantitative analysis by various methods.
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Methyl nicotinate is found in alcoholic beverages
- Applications in muscle and joint pain preparations
Medchemexpress LLC Spermidine-d6 | 2514812-10-1 | 96.1% | 1 MG
Spermidine-d6 is a deuterium-labeled spermidine that helps maintain cell membrane stability, increases antioxidant enzyme activities, improves photosystem II (PSII), and enhances relevant gene expression. It significantly reduces H2O2 and O2.- contents.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC N-2-hydroxyethylpiperazine-N'-ethanesulfonic acid-d18 | 203805-87-2 | MFCD00006158 | 99.9% | 256.42 | C8D18N2O4S | 10 MG
Deuterium-labeled HEPES buffer provided as a high-purity solid for analytical and biochemical applications. It serves as a nonvolatile zwitterionic buffering agent effective at pH 6.8-8.2 and is intended for use as a tracer or internal standard in quantitative NMR, GC-MS, and LC-MS work.
- High isotopic enrichment suitable for NMR and mass spectrometry.
- High purity (99.9%) for analytical reliability.
- Effective buffering range pH 6.8-8.2 for biological assays.
- Available in small milligram quantities for tracer studies.
- Stable solid form with defined low-temperature storage recommendations.
Medchemexpress LLC Nicorandil-d4 | 1132681-23-2 | 99.8% | 1 MG
Nicorandil-d4 (SG-75-d4) is the deuterium-labeled Nicorandil. Nicorandil (SG-75) is a potent potassium channel activator that targets vascular nucleoside diphosphate-dependent K+ channels and cardiac ATP-sensitive K+ channels (KATP). It is a nicotinamide ester with vasodilatory and cardioprotective effects, with potential use for angina and ischemic heart diseases. Deuteration has gained attention due to its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Targets vascular nucleoside diphosphate-dependent K+ channels and cardiac ATP-sensitive K+ channels (KATP).
- Has vasodilatory and cardioprotective effects.
- Potential for angina and ischemic heart diseases.
Medchemexpress LLC Octopamine-d4 hydrochloride | 1219803-62-9 | MFCD11983520 | 98.3% | 10 MG
Octopamine-d4 hydrochloride is the deuterium-labeled (d4) hydrochloride salt of octopamine supplied as a solid stable-isotope standard for analytical and research use. It is intended for use as an internal standard in mass spectrometry, tracer studies, and quantitative analyses where isotopic labeling improves accuracy.
- Deuterium-labeled internal standard for mass spectrometry and quantitative analysis.
- High purity (~98.3%) suitable for analytical applications.
- Solid, light brown to brown appearance for easy handling and storage.
- Recommended storage: sealed at 4°C; in solvent, -80°C up to 6 months.
- Available in small mg pack sizes for analytical workflows.
Medchemexpress LLC 2,2'-bipyridine-d8 | 32190-42-4 | 99.3% | 164.24 g/mol | C10D8N2 | 5 MG
2,2′-Bipyridine-d8 is the deuterium-labeled isotopologue of 2,2′-bipyridine supplied for research use. It is intended as an analytical standard and tracer for quantitative analysis by NMR, GC-MS, and LC-MS, and is provided with supporting documentation for laboratory use.
- High chemical purity (99.3%).
- Isotope-labeled tracer suitable as an internal standard for NMR, GC-MS, and LC-MS.
- Available in small milligram quantities for analytical workflows.
- Includes datasheet, safety data sheet, and certificate of analysis.
- Intended for research use only; not for human or clinical applications.
Medchemexpress LLC Alanine-2,3,3,3-d4 | 53795-92-9 | MFCD00084108 | 99.8% | 93.12 g/mol | C3H3D4NO2 | 10 MG
Alanine-2,3,3,3-d4 is a deuterium-labeled form of alanine used as a stable-isotope tracer and internal standard for quantitative analysis. It is intended for analytical workflows in which accurate quantitation and tracing are required, and is supplied in milligram pack sizes suitable for NMR, GC-MS, and LC-MS applications.
- Deuterium-labeled for isotope tracing and internal standardization.
- High purity (99.8%) for accurate quantitation.
- Suitable for NMR, GC-MS, and LC-MS applications.
- Available in multiple small milligram pack sizes for analytical use.
- Molecular weight 93.12 g/mol and CAS 53795-92-9 for unambiguous identification.
Sigma Aldrich Fine Chemicals Biosciences Methanol d4 99 atom D
Methanol-d4 (CD3OD) is a deuterated NMR solvent. It is useful in NMR-based research and analyses. Absolute infrared absorption intensities of CD3OD have been reported between 8000 and 350cm-1.1
Medchemexpress LLC Exatecan-d5 mesylate (DX8951f-d5) | 2819276-88-3 | 99.8% | 536.58 | 100 MG
Exatecan-d5 mesylate (DX8951f-d5) is a deuterium-labeled compound used as a tracer and internal standard for quantitative analysis by methods like NMR, GC-MS, or LC-MS. Its unlabeled form, Exatecan mesylate, is a DNA topoisomerase I inhibitor used in cancer research.
- Deuterium-labeled compound for tracer and internal standard applications.
- Stable heavy isotopes can affect pharmacokinetic and metabolic profiles.
- Used in cancer research as a DNA topoisomerase I inhibitor.
- High purity of 99.8%.
Medchemexpress LLC Methyl palmitate-13C16 | 112-39-0 | 99.8% | 286.33 | C13C16H34O2 | 10 MG
Methyl palmitate-13C16 is a 13C-labeled isotopologue of methyl palmitate supplied as a high-purity stable-isotope reference for analytical workflows and mass spectrometry. It is intended for use as an internal standard to improve quantitation and peak identification in LC-MS and GC-MS analyses.
- 13C16-labeled isotopologue for isotope-dilution quantitation.
- High purity: 99.8%.
- Molecular formula C13C16H34O2; molecular weight 286.33 g/mol.
- Available in small preweighed quantities, including 10 MG.
- Suitable as an internal standard for mass spectrometry analyses.
Medchemexpress LLC Pregn-4-ene-3,20-dione-d9 | 15775-74-3 | MFCD01317491 | 99.7% | 323.52 | C21H21D9O2 | 10 MG
Progesterone-d9 is a deuterium-labeled analogue of the endogenous steroid hormone progesterone, provided as a solid for research use. It is intended for use as a tracer and internal standard in quantitative analytical methods and pharmacokinetic or metabolic studies.
- Deuterium-labeled tracer and internal standard for NMR, GC-MS, and LC-MS.
- Chemical formula C21H21D9O2.
- Molecular weight 323.52 g/mol.
- Supplier-listed purity ~99.7% (verify for critical use).
- Appearance: white to light yellow solid.
- Solubility: DMSO 50 mg/mL; may require sonication and warming.
- Storage: powder at -20°C; in solvent -80°C (6 months) or -20°C (1 month).
- Typical pack size: 10 mg.
Medchemexpress LLC Salbutamol-d3 | 1219798-60-3 | 98.7% | 5 MG
Salbutamol-d3 (Albuterol-d3) is a deuterium-labeled Salbutamol and an orally active short-acting β2-adrenergic receptor agonist. It promotes tumorigenesis in gastric cancer cells through the β2-AR/ERK/EMT pathway and can relax bronchial smooth muscle, used to study bronchospasm induced by asthma and chronic obstructive pulmonary disease.
- Used as a tracer.
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.