Isotopically Labeled Compounds
Cambridge Isotope Laboratories 5beta-Pregnan-3Alpha 11beta 21-triol-20-one (2 2 3 4 4-D5 98%) CP 95% 1 mg
5beta-Pregnan-3Alpha 11beta 21-triol-20-one (2 2 3 4 4-D5 98%) CP 95% 1 mg
Medchemexpress LLC Sofosbuvir-d6 | 1868135-06-1 | 98.07% | 535.49 | 2 MG
Sofosbuvir-d6 is the deuterium-labeled Sofosbuvir, an active inhibitor of HCV RNA replication. It demonstrates potent anti-hepatitis C virus (HCV) activity and is intended for research use only.
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stable heavy isotopes incorporated for drug development
- Potential to affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Carboplatin-d4 | 41575-94-4 | 99.0% | 375.28 | 5 MG
Carboplatin-d4 is the deuterium labeled Carboplatin. It is a DNA synthesis inhibitor that binds to DNA, inhibits replication and transcription, and induces cell death. This compound is a derivative of CDDP and a potent anti-cancer agent, intended for research use only.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Atazanavir-d6 | 1092540-50-5 | 99.3% | 710.89 | 1 MG
Atazanavir-d6 is a deuterium-labeled variant of Atazanavir (BMS-232632), a highly selective HIV-1 protease inhibitor. It was the first protease inhibitor approved for once-daily administration. Atazanavir-d6 acts as a substrate and inhibitor of CYP3A4, and also inhibits and induces P-glycoprotein (P-gp). It has also been identified as a SARS-CoV 3CLpro inhibitor with an IC50 of 3.49 μM. Deuterium labeling incorporates stable heavy isotopes into the drug molecule, which can impact pharmacokinetic and metabolic profiles and serve as tracers for quantitative analysis.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
![Medchemexpress LLC Acetic acid, [2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl-2,2,3,3,5,5,6,6-d8]ethoxy]- | 774596-22-4 | 96.5% | 396.94 | 1 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000384304-logo.png-250.jpg){kind=logo}
Medchemexpress LLC Acetic acid, [2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl-2,2,3,3,5,5,6,6-d8]ethoxy]- | 774596-22-4 | 96.5% | 396.94 | 1 MG
Cetirizine-d8 is a deuterium labeled Cetirizine. It is a specific, orally active, and long-acting histamine H1-receptor antagonist with antiallergic properties, inhibiting eosinophil chemotaxis during the allergic response.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Agomelatine-d3 | 1079389-38-0 | 98.0% | 246.32 | 1 MG
Agomelatine-d3 is the deuterium labeled version of Agomelatine. It functions as a specific agonist of MT1 and MT2 receptors and a selective 5-HT2C receptor antagonist.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Indole-13C | 85597-55-3 | 118.14 | 100 MG
Indole-13C is the 13C labeled Indole. Indole is an endogenous metabolite.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC CER3-d9 | 2260669-53-0 | 99% | 564.97 | 1 MG
CER3-d9 is a deuterium-labeled version of CER3. It is intended for research use only. This compound can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Deuteration, the process of incorporating stable heavy isotopes of hydrogen, carbon, and other elements into drug molecules, has shown potential in affecting the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC D-Xylulose-1-13C | 131771-46-5 | 99.2% | 151.12 | 5 MG
D-Xylulose-1-13C is a 13C labeled D-Xylulose, which serves as a precursor of the pentiol D-arabi. This compound is suitable for use as a tracer and an internal standard in quantitative analysis methods such as NMR, GC-MS, or LC-MS. Stable heavy isotopes of elements like carbon are incorporated into drug molecules for quantitation during drug development, with deuteration potentially affecting pharmacokinetic and metabolic profiles.
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Suitable for laboratory chemical applications
- Can be used in the manufacture of substances
Cayman Chemical CytosIn-13C 15N2 10mg
An internal standard for the quantification of cytosine by GC- or LC-MS
Medchemexpress LLC L-Glucose-13C | 478519-02-7 | 98.0% | 181.15 | 10 MG
L-Glucose-13C is the ⁴³C labeled L-Glucose, which is an enantiomer of D-glucose and can promote food intake. This compound is intended for research use only and not for patient consumption. It can be utilized as a tracer and an internal standard in quantitative analysis.
- Can be used as a tracer and internal standard
- Suitable for quantitative analysis by NMR, GC-MS, or LC-MS
- ⁴³C labeled L-Glucose
- Enantiomer of D-glucose
- Promotes food intake
Cambridge Isotope Laboratories DL-Norcotinine (3 4 5-13C3 99%) 100 ug/mL in acetonitrile 1 2 mL
DL-Norcotinine (3 4 5-13C3 99%) 100 ug/mL in acetonitrile 1 2 mL
Medchemexpress LLC Methanol-d1 | 1455-13-6 | MFCD00044213 | 99.8% | 33.05 g·mol⁻¹ | CH3DO | 5 G
Methanol-d1 (CH3DO) is the deuterium-labeled form of methanol used as an isotopically enriched solvent and tracer in analytical and synthetic chemistry. It provides a single deuterium substitution that aids NMR spectral interpretation and isotopic labeling studies. Typical properties include CAS 1455-13-6 and a molecular weight of 33.05 g·mol⁻¹.
- High isotopic purity (reported 99.8%).
- Useful as an NMR solvent and spectral reference.
- Suitable for mass spectrometry and isotopic labeling experiments.
- Volatile, low boiling solvent-handle in a fume hood.
- Supplied in small research-scale packages (5 g) for laboratory use.
Cayman Chemical Lnsoprazole-d4 1mg
An internal standard for the quantification of lansoprazole by GC- or LC-MS