Isotopically Labeled Compounds
Medchemexpress LLC D-Glucose-13C | 101615-88-7 | 99.9% | 5 MG
D-Glucose-13C is the 13C labeled form of D-Glucose. D-Glucose, also known as Glucose, is a monosaccharide and a crucial carbohydrate in biological systems. It functions as a carbohydrate sweetener and plays a vital role in general metabolism. Additionally, D-Glucose acts as a critical signaling molecule, linking cellular metabolic status with biotic and abiotic stress responses.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS.
- Stable heavy isotopes like carbon-13 are incorporated into drug molecules for quantitation during drug development.
- Deuteration, a similar process, has been noted for its potential to influence the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Terazosin-d8 | 1006718-20-2 | 99.2% | 1 MG
Terazosin-d8 is a deuterium labeled version of Terazosin, a quinazoline derivative and a competitive, orally active α1-adrenoceptor antagonist. It functions by relaxing blood vessels and opening the bladder, showing potential for treating benign prostatic hyperplasia (BPH) and high blood pressure. Deuteration can affect the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Competitive and orally active α1-adrenoceptor antagonist
- Relaxing blood vessels and opening the bladder
- Potential for benign prostatic hyperplasia (BPH) and high blood pressure treatment
Medchemexpress LLC Amitriptyline-d6 hydrochloride | 203645-63-0 | 99.9% | 1 MG
Amitriptyline-d6 hydrochloride is the deuterium-labeled version of Amitriptyline hydrochloride, an orally active tricyclic antidepressant (TCA). It primarily works by blocking SERT (Ki = 3.45 nM) and NET (Ki = 13.3 nM), which increases the concentrations of 5-hydroxytryptamine (5-HT) and norepinephrine (NE) in the synaptic cleft. It also acts as an agonist at α2A and TrkA/TrkB receptors, contributing to analgesic and neurotrophic effects by inhibiting cell apoptosis.
- Increases concentrations of 5-hydroxytryptamine and norepinephrine in synaptic cleft
- Contributes to analgesic and neurotrophic effects
- Reduces inflammation, angiogenesis, and fibrosis
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Deuteration can influence pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Tentoxin-d3 | 1426437-58-2 | 417.52 | C22H27D3N4O4 | 250 UG
Tentoxin-d3 is the deuterium-labeled analogue of tentoxin, provided as a small-quantity research standard for analytical applications such as mass spectrometry and metabolic tracing. Molecular formula C22H27D3N4O4; molecular weight 417.52; CAS 1426437-58-2.
- Deuterium-labeled (d3) analogue for use as an internal standard in mass spectrometry
- Suitable for metabolic tracing and analytical method development
- Provided in a low microgram quantity for sensitive assays
- Molecular weight 417.52; molecular formula C22H27D3N4O4
- Store powder at -20°C for long-term stability
Medchemexpress LLC D-Fructose-4-13C | 84270-09-7 | 50 MG
D-Fructose-4-13C is a 13C labeled form of D-Fructose, a naturally occurring monosaccharide found in many plants. It is a solid with an off-white to light yellow appearance and is suitable for research applications. Stable heavy isotopes, such as those in this product, are used as tracers for quantitation during drug development processes.
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Supports research on pharmacokinetic and metabolic profiles of drugs
- Appearance: solid, off-white to light yellow
Medchemexpress LLC D-Fructose-d4 | 478518-49-9 | 5 MG
D-Fructose-d4 is the deuterium labeled D-Fructose, a naturally occurring monosaccharide found in many plants.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Sodium propionate-d5 | 202529-18-8 | 99.9% | 50 MG
Sodium propionate-d5 | 202529-18-8 | 99.9% | 50 MG
Medchemexpress LLC Sodium propionate-d5 | 202529-18-8 | 99.91% | 100 MG
Sodium propionate-d5 | 202529-18-8 | 99.91% | 100 MG
Medchemexpress LLC Fenofibric acid-d6 | 1092484-69-9 | MFCD06658651 | 99.6% | 1 MG
Fenofibric acid-d6 is the deuterium-labeled form of Fenofibric acid, which is an active metabolite of fenofibrate. It acts as a PPAR activator and also inhibits COX-2 enzyme activity. This compound is useful as a tracer or as an internal standard for quantitative analysis.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Active metabolite of fenofibrate
- PPAR activator
- Inhibits COX-2 enzyme activity
Medchemexpress LLC L-tyrosine-d5 | 1226919-57-8 | MFCD18782928 | 99.9% | 186.22 | C9H6D5NO3 | 10 MG
L-Tyrosine-d5 is a deuterium-labeled stable isotope of the amino acid L-tyrosine supplied as a white to off-white powder for research use. It is intended for use as an internal standard or tracer in mass spectrometry and metabolic studies, providing high isotopic fidelity for quantitative analyses.
- High isotopic and chemical purity for analytical standards and quantitative assays.
- Supplied as a solid powder with defined storage recommendations for stability.
- Suitable as an internal standard in LC-MS/MS and metabolic tracing workflows.
- Soluble in acidic aqueous solutions; limited solubility in DMSO without ultrasonic assistance.
- Recommended storage: powder at -20°C for long-term stability.
Medchemexpress LLC D-(+)-galactose-13C-2 | 478518-56-8 | 99.9% | 181.15 g/mol | C5^13CH12O6 | 10 MG
D-Galactose-13C-2 is D-galactose labeled with a single 13C isotope at the C-2 position. It is supplied as a stable isotope-labeled standard for metabolic tracing, isotope dilution quantification, and mass spectrometry applications; for research use only.
- 13C label at C-2 for metabolic tracing.
- High chemical purity: 99.9%.
- Molecular weight 181.15 g/mol.
- CAS number 478518-56-8.
- Supplied as a 10 mg vial suitable for analytical use.
- Stable isotope standard for quantitative and qualitative assays.
Medchemexpress LLC 1-hexadecanol-d5 | 1219799-18-4 | 99.2% | 10 MG
1-Hexadecanol-d5 is the deuterium-labeled analogue of 1-hexadecanol, provided as a high-purity stable isotope standard for analytical use. It is supplied as a white to off-white solid and is intended for use as a tracer or internal standard in quantitative NMR, GC-MS, and LC-MS analyses.
- High purity: 99.20%.
- Molecular formula: C16H29D5O; molecular weight: 247.47.
- Available in small analytical pack sizes, including 10 mg.
- Soluble in DMSO; warming and sonication can improve dissolution.
- Suitable as a tracer and internal standard for quantitative analysis.
- Storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
- Appearance: white to off-white solid.
Medchemexpress LLC Piribedil-d8 | 1398044-45-5 | 99.8% | 1 MG
Piribedil-d8 is a deuterium-labeled analog of Piribedil, an antiparkinsonian agent known for its activity as a dopamine D2 and D3 agonist and α2-adrenoceptors antagonist. This compound serves as a valuable tracer and internal standard for quantitative analysis in various analytical techniques, including NMR, GC-MS, and LC-MS.
- Can be used as a tracer
- Functions as an internal standard for quantitative analysis
- Acts as a dopamine D2 and D3 agonist
- Serves as an α2-adrenoceptors antagonist
- Inhibits MLL1 methyltransferase activity
- Potential for research in Parkinson's disease, circulatory disorders, and cancers
Medchemexpress LLC Diethyltoluamide-d7 | 1219799-37-7 | 98.5% | 5 MG
Diethyltoluamide-d7 is the deuterium-labeled form of Diethyltoluamide, which is widely recognized as the primary active ingredient in insect repellents. It is formulated to offer protection against a broad spectrum of biting insects, including mosquitoes, ticks, fleas, chiggers, and leeches. This compound is intended for research purposes only.
- Deuterium labeled diethyltoluamide.
- Can be used as a tracer.
- Can serve as an internal standard for quantitative analysis using techniques like NMR, GC-MS, or LC-MS.
- Stable heavy isotopes, such as deuterium, are incorporated into drug molecules for quantitation during drug development.
- Deuteration can potentially influence the pharmacokinetic and metabolic profiles of drugs.