Isotopically Labeled Compounds
Medchemexpress LLC Oxybutynin-d11 chloride | 1185151-95-4 | 97.4% | 5 MG
Oxybutynin-d11 (chloride) is the deuterium-labeled version of Oxybutynin chloride. Oxybutynin chloride acts as an anticholinergic agent, inhibiting vascular Kv channels in a concentration-dependent manner, with an IC50 of 11.51 μM. Deuterium substitution, as seen in this product, has been studied for its potential to alter the pharmacokinetic and metabolic profiles of drugs.
- It is a deuterium-labeled compound.
- It serves as a tracer.
- It can be used as an internal standard for quantitative analysis through techniques such as NMR, GC-MS, or LC-MS.
- It is intended for research use only.
Medchemexpress LLC Acetamiprid-d3 | 1353869-35-8 | 99.9% | 1 MG
Acetamiprid-d3 is the deuterium labeled Acetamiprid. Acetamiprid is a neonicotinoid insecticide and a nAChR agonist.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration, the incorporation of stable heavy isotopes into drug molecules, has the potential to affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Indomethacin-d4 Methyl Ester | 1217064-61-3 | 98.4% | C20H14D4ClNO4 | 1 MG
Indomethacin-d4 Methyl Ester is a deuterium-labeled form of Indomethacin, a potent, blood-brain permeable, and nonselective inhibitor of both COX-1 and COX-2 enzymes. It demonstrates inhibitory activity with IC50s of 18 nM for human COX-1 and 26 nM for COX-2 in CHO cells. This compound has also been observed to disrupt autophagic flux by interfering with the normal function of lysosomes.
- Deuterium labeled derivative of indomethacin
- Potent and nonselective COX-1 and COX-2 inhibitor
- Blood-brain barrier permeable
- Disrupts autophagic flux through lysosomal interference
- Useful as a tracer or internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Febuxostat-d7 | 1285539-74-3 | 99.1% | C16H9D7N2O3S | 1 MG
Febuxostat-d7 is a deuterium labeled form of Febuxostat, a selective xanthine oxidase inhibitor with a Ki of 0.6 nM. It serves as a tracer and an internal standard for quantitative analysis. Deuterated compounds are used as tracers for quantitation during drug development and can affect pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Deuterium labeled Febuxostat
- Selective xanthine oxidase inhibitor with a Ki of 0.6 nM
- For research use only
Medchemexpress LLC Terbuthylazine-d5 | 222986-60-9 | 99.1% | 1 MG
Terbuthylazine-d5 is a deuterium labeled version of Terbuthylazine, which acts as an inhibitor of acetolactate synthase (ALS) and is a selective herbicide. Deuteration has garnered attention due to its potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Octanoic acid-d15 | 69974-55-6 | 99.9% | 159.30 | 25 MG
Octanoic acid-d15 is the deuterium labeled Octanoic acid. Octanoic acid (Caprylic acid) is an oily liquid with a slightly unpleasant rancid taste and is used commercially in the production of esters used in perfumery and also in the manufacture of dyes.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration has the potential to affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Lapatinib-d4 (GW572016-d4; GW2016-d4) | 1184263-99-7 | 99.0% | C29H22D4ClFN4O4S | 5 MG
Lapatinib-d4 is the deuterium-labeled version of Lapatinib, a potent, orally active inhibitor of the ErbB-2 and EGFR tyrosine kinase domains. It is suitable for research use only. Deuteration, which involves incorporating stable heavy isotopes into drug molecules, serves as a tracer for quantitation during drug development and can influence the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Incorporates stable heavy isotopes to influence pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC 1,6-anhydro-β-D-glucopyranose-d7 | 2483832-05-7 | 99.9% | 169.18 g/mol | C6H3D7O5 | 10 MG
Levoglucosan-d7 is a deuterium-labeled analogue of levoglucosan (1,6-anhydro-β-D-glucopyranose) used as a stable-isotope standard and tracer in analytical chemistry, particularly mass spectrometry and environmental analysis.
- Deuterium-labeled internal standard for mass spectrometry.
- High purity (99.9%) for accurate quantitation.
- Available in small analytical pack sizes, such as 10 mg.
- Solid powder format with defined storage conditions to preserve stability.
- Molecular formula C6H3D7O5, molecular weight 169.18 g/mol.
Medchemexpress LLC Melperone-d4 hydrochloride | 1219798-80-7 | 99.8% | 1 MG
Melperone-d4 hydrochloride is a deuterium-labeled form of Melperone hydrochloride, a butyrophenone with atypical antipsychotic properties. It functions as a multireceptor antagonist, targeting 5-HT2A, dopamine D2, α1-adrenergic, and α2-adrenergic receptors, along with weaker binding to other receptors. It also inhibits CYP2D6. This compound is valuable for research into schizophrenia and agitation in the elderly.
- Deuterium-labeled compound
- Atypical antipsychotic properties
- Functions as a multireceptor antagonist
- Targets 5-HT2A, dopamine D2, α1-adrenergic, and α2-adrenergic receptors
- Inhibits CYP2D6
- Useful for research on schizophrenia and agitation in the elderly
- Can be used as a tracer
- Suitable as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Iohexol-d5 | 928623-33-0 | 100.0% | 1 MG
Iohexol-d5 is a deuterium-labeled derivative of Iohexol, a widely recognized radiographic contrast agent. This product is suitable for various imaging applications including myelography, computerized tomography, and MicroCT imaging. It also serves as a valuable tool in quantitative analysis as a tracer or internal standard for techniques like NMR, GC-MS, and LC-MS.
- Deuterium-labeled compound for research applications
- Functions as a radiographic contrast agent
- Useful as a tracer in analytical studies
- Can be used as an internal standard for quantitative analysis
- Suitable for myelography and computerized tomography
Medchemexpress LLC (±)-Naproxen-d3 | 958293-79-3 | MFCD22572922 | 99.8% | 233.28 g/mol | C14H11D3O3 | 10 MG
(±)-Naproxen-d3 is the deuterium-labeled form of naproxen used as an analytical reference standard and tracer. It is intended as an internal standard for quantitative and metabolic studies and supports accurate method development and validation in spectrometric and chromatographic workflows.
- Deuterium-labeled internal standard for quantitative analysis.
- Suitable for NMR, GC-MS, and LC-MS applications.
- High chemical and isotopic purity for reliable quantitation.
- Supplied in small, accurately weighed quantities for analytical work.
- Molecular formula C14H11D3O3 and molecular weight 233.28 g/mol.
Medchemexpress LLC Acetaminophen-d3 | 60902-28-5 | MFCD06658893 | 99.0% | 154.18 g/mol | C8H6D3NO2 | 10 MG
Acetaminophen-d3 is the deuterium-labeled analogue of acetaminophen used as a tracer and internal standard for quantitative analysis by NMR, GC-MS, and LC-MS. It is supplied as a high-purity solid suitable for analytical research applications.
- High-purity deuterium-labeled standard (99.0%).
- Intended for use as tracer or internal standard in NMR, GC-MS, and LC-MS quantitative analysis.
- Supplied as a solid for analytical workflows and small-scale assays.
- Stable when stored as a powder at -20°C for extended periods.
Medchemexpress LLC Propan-2-amine-d7 h 25mg
Propan-2-amine-d7 (hydrochloride) is the deuterium labeled Propan-2-amine hydrochloride[1]
Medchemexpress LLC Balsalazide-d4 | 2714315-25-8 | 99.9% | 1 MG
Balsalazide-d4 is a deuterium-labeled form of Balsalazide. It can be used as a tracer and as an internal standard for quantitative analysis. Deuterium substitution can influence the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Suppresses colitis-associated carcinogenesis through modulation of the IL-6/STAT3 pathway
Medchemexpress LLC 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-propyl-d7 | 1392208-04-6 | 99.6% | 1 MG
(Rac)-Ropivacaine-d7 is a stable isotope-labeled compound, identified as 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-propyl-d7. It appears as a white to off-white solid with an isotopic enrichment of 99.11%. This product is intended for research use only and should be handled by qualified personnel in appropriately equipped facilities.
- High purity of 99.6% (HPLC)
- Stable under recommended storage conditions
- Ideal for laboratory chemical applications and substance manufacturing
- For research use only