Isotopically Labeled Compounds
Medchemexpress LLC Nifedipine-d6 (BAY-a-1040-d6) | 1188266-14-9 | 1 MG
Nifedipine-d6 (BAY-a-1040-d6) is a deuterium labeled nifedipine, which acts as a potent calcium channel blocker. It is intended for research use only. Deuteration, the incorporation of stable heavy isotopes of hydrogen into drug molecules, has gained attention for its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Acetylcholine-d4 chloride | 344298-94-8 | 99.2% | 1 MG
Acetylcholine-d4 (chloride) is the deuterium labeled Acetylcholine chloride. Acetylcholine chloride (ACh chloride), a neurotransmitter, is a potent and BBB-permeable cholinergic agonist. It modulates the activity of dopaminergic (DAergic) neurons through the stimulation of nicotinic acetylcholine receptors (nAChRs) and inhibits p53 mutant peptide aggregation in vitro. Stable heavy isotopes have been incorporated into drug molecules for quantitation during drug development, and deuteration has the potential to affect pharmacokinetic and metabolic profiles.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Modulates dopaminergic neuron activity
- Inhibits p53 mutant peptide aggregation in vitro
- Deuterium labeled for potential pharmacokinetic and metabolic profile effects
Medchemexpress LLC Acetylcholine-d9 bromide | 93449-32-2 | 98.9% | 5 MG
Acetylcholine-d9 bromide is a deuterium labeled Acetylcholine bromide, commonly used for quantitative analysis in drug development.
- Used as a tracer.
- Internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Incorporates stable heavy isotopes like deuterium.
- Potential to affect pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Sulfadimethoxine-d6 | 73068-02-7 | 99.0% | 1 MG
Sulfadimethoxine-d6 is a deuterium-labeled version of Sulfadimethoxine, a sulfonamide antibiotic used to treat various infections. It is a stable isotope-labeled compound primarily used as a tracer and internal standard in quantitative analysis.
- Deuterium-labeled compound
- Used as a tracer
- Internal standard for NMR, GC-MS, or LC-MS analysis
- Intended for research use only
- Stable under recommended storage conditions
- Not classified as a hazardous substance or mixture
Medchemexpress LLC Lamotrigine-d3 | 1132746-94-1 | 1 MG
Lamotrigine-d3 is the deuterium labeled Lamotrigine. Lamotrigine (BW430C) is a potent and orally active anticonvulsant or antiepileptic agent. It selectively blocks voltage-gated Na+ channels, stabilizing presynaptic neuronal membranes and inhibiting glutamate release. Lamotrigine can be used for the research of epilepsy, focal seizure, among others. It is intended for research use only. This compound can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Adenosine-d | 109923-50-4 | 100.0% | 5 MG
Adenosine-d | 109923-50-4 | 100.0% | 5 MG
Medchemexpress LLC Diuron-d6 | 1007536-67-5 | 99.5% | 1 MG
Diuron-d6 is a deuterium-labeled form of Diuron, an orally active phenylurea herbicide. It functions by inhibiting photosynthesis in plants, specifically by blocking the formation of ATP and NADH. Diuron-d6 also increases the production of Reactive Oxygen Species (ROS) and the expression of p53 in certain cell lines, and has shown herbicidal activity against various broadleaf and grass weeds. It has been noted to promote bladder cancer in some studies and is applicable in breast cancer research.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Nad+-13c5 ammonium | 53-84-9 | 98.9% | 1 MG
NAD+-13C5 (ammonium) is a 13C labeled NAD+ compound intended for research use only. This compound can be utilized as a tracer or as an internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS. Stable heavy isotopes are incorporated into drug molecules primarily as tracers for quantitation during drug development. Shipping is at room temperature in the continental US, with variations elsewhere. Solid storage requires -20°C, sealed, away from moisture and light. If in solvent, store at -80°C for 6 months or -20°C for 1 month, also sealed and away from moisture and light.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Tolbutamide-d9 | 1219794-57-6 | 99.0% | 1 MG
Tolbutamide-d9 is a deuterium-labeled Tolbutamide. Tolbutamide is classified as a first-generation potassium channel blocker and a sulfonylurea oral hypoglycemic agent. This compound can be used as a tracer or an internal standard for quantitative analysis.
- Used as a tracer in drug development
- Serves as an internal standard for quantitative analysis by techniques such as NMR, GC-MS, or LC-MS
- Incorporates stable heavy isotopes into drug molecules
- Deuteration may influence pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Levofloxacin-13C,d3 | 1261398-33-7 | 98.8% | 1 MG
Levofloxacin-13C,d3 is a labeled version of Levofloxacin, an antibiotic commonly used to treat a variety of bacterial infections. This specific compound incorporates 13C and deuterium isotopes, making it suitable for research applications where isotopically labeled compounds are required, such as in pharmacokinetic studies or as an internal standard in analytical methods.
- Isotopically labeled for research applications
- Suitable for pharmacokinetic studies
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Avanti Polar Lipids 9-Octadecenoic acid (9Z)-, 1,1'-[phosphinicobis[oxy[(2R)-2-hydroxy-3,1-propanediyl]]] ester, ammonium salt (1:1) | 1246303-13-8 | 792.1 g/mol | 5MG
9-Octadecenoic acid (9Z)-, 1,1'-[phosphinicobis[oxy[(2R)-2-hydroxy-3,1-propanediyl]]] ester, ammonium salt (1:1) | 1246303-13-8 | 792.1 g/mol | 5MG
Cambridge Isotope Laboratories Dimethyl Sulfoxide-d6, 2206-27-1, MFCD00002090, 100 g
Chemical Formula: CD3SOCD3, MW: 84.17, 99.9%, Synonyms: DMSO-D6; Methyl sulfoxide-D6; Hexadeuterodimethyl sulfoxide.
Cambridge Isotope Laboratories Phenol-D6 (D, 98%), 13127-88-3, MFCD00002144, 5g
Molecular Formula C6D6O, Chemical Purity 98%, Molecular Weight 100.149
Sigma Aldrich Fine Chemicals Biosciences Methanol d4 34 10034 10G
Methanol-d4 (CD3OD) is a deuterated NMR solvent useful in NMR-based research and analyses. Absolute infrared absorption intensities of CD3OD have been reported between 8000 and 350cm-1.
Cayman Chemical Ivermectin-d2, Purity: ≥99% deuterated forms (d1-d2), 1 mg
An internal standard for the quantification of ivermectin by GC- or LC-MS