Isotopically Labeled Compounds
Medchemexpress LLC Proguanil-d6 (hydrochloride) | 1 MG
Proguanil-d6 (hydrochloride) is a deuterium-labeled form of Proguanil hydrochloride, an antimalarial proagent metabolized to the active metabolite Cycloguanil. It functions as a dihydrofolate reductase (DHFR) inhibitor. This product is a solid, intended for research use only, and suitable for use as a laboratory chemical in the manufacture of substances.
- Deuterium-labeled compound
- Functions as an antimalarial proagent
- Metabolized to the active metabolite cycloguanil
- Dihydrofolate reductase (DHFR) inhibitor
- Useful as a laboratory chemical
- Appears as a solid
- Intended for research use only
Medchemexpress LLC L-alanine-2-d1 | 21386-65-2 | MFCD00084105 | >=98.0% | 90.10 g/mol | C3H6DNO2 | 500 MG
L-Alanine-2-d1 is a deuterium-labeled analogue of L-alanine supplied for laboratory research. It is used as a stable isotope tracer and as an internal standard to improve accuracy and quantitation in analytical workflows such as NMR, GC-MS, and LC-MS.
- Deuterium-labeled tracer for metabolic and pharmacokinetic studies.
- Suitable as internal standard for quantitative NMR, GC-MS, and LC-MS analyses.
- White to off-white solid powder for laboratory handling.
- High chemical purity (≥98%) for analytical reliability.
- Stable under cold storage: powder -20°C (up to 3 years) or 4°C (up to 2 years).
- Molecular formula C3H6DNO2; molecular weight ~90.10 g/mol.
Medchemexpress LLC L-Ascorbic-6,6-C-d2 acid | 82977-10-4 | 99.90% | 5 MG
L-Ascorbic acid-d2 is the deuterium-labeled L-Ascorbic acid. This compound acts as an electron donor and is an endogenous antioxidant agent. It selectively inhibits Cav3.2 channels with an IC50 of 6.5 μM and is also a collagen.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Cayman Chemical Acephate-d3 1mg
An internal standard for the quantification of acephate by GC- or LC-MS
Medchemexpress LLC 4-(N-Nitrosomethylamino)-1-(3-pyridyl)-1-butanone-d4 | 764661-24-7 | 99.7% | 10 MG
NNK-d4 is a deuterium labeled compound, used as a tracer and internal standard for quantitative analysis by methods like NMR, GC-MS, or LC-MS. Its deuterium substitution can affect pharmacokinetic and metabolic profiles, making it valuable in drug development and research.
- Used as a tracer and internal standard
- Suitable for quantitative analysis by NMR, GC-MS, or LC-MS
- Deuterium substitution may influence pharmacokinetic and metabolic profiles
- White to off-white solid appearance
- Purity of 99.65%
Medchemexpress LLC Amantadine-d6 | 1219805-53-4 | 98.1% | 5 MG
Amantadine-d6 is the deuterium labeled Amantadine. Amantadine (1-Adamantanamine) is an orally active and potent antiviral agent effective against influenza A viruses. It inhibits various ion channels, including NMDA and M2, as well as Coronavirus ion channels. It also exhibits anti-orthopoxvirus and anticancer activities. Amantadine-d6 can serve as a tracer and an internal standard for quantitative analysis, with deuteration potentially influencing pharmacokinetic and metabolic profiles of drugs. Applications include research for Parkinson's disease, postoperative cognitive dysfunction (POCD), and COVID-19.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stable heavy isotopes incorporated into drug molecules for quantitation
- Potential to affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Chlorpromazine-d6 hydrochloride | 1228182-46-4 | 99.9% | 1 MG
Chlorpromazine-d6 (hydrochloride) is the deuterium labeled Chlorpromazine. Chlorpromazine is an inhibitor of dopamine receptor, 5-HT receptor, potassium channel, and sodium channel. It is used for research purposes only and not sold to patients. This compound can be used as a tracer or as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Deuteration, the incorporation of stable heavy isotopes into drug molecules, has potential to affect pharmacokinetic and metabolic profiles of drugs.
- Deuterium labeled Chlorpromazine
- Inhibits dopamine receptor, 5-HT receptor, potassium channel, and sodium channel
- Used as a tracer or internal standard for quantitative analysis
- Deuteration can affect pharmacokinetic and metabolic profiles
Medchemexpress LLC Tolbutamide-d9 | 1219794-57-6 | 99.0% | 1 MG
Tolbutamide-d9 is a deuterium-labeled Tolbutamide. Tolbutamide is classified as a first-generation potassium channel blocker and a sulfonylurea oral hypoglycemic agent. This compound can be used as a tracer or an internal standard for quantitative analysis.
- Used as a tracer in drug development
- Serves as an internal standard for quantitative analysis by techniques such as NMR, GC-MS, or LC-MS
- Incorporates stable heavy isotopes into drug molecules
- Deuteration may influence pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Sulfadimethoxine-d6 | 73068-02-7 | 99.0% | 5 MG
Sulfadimethoxine-d6 is the deuterium-labeled form of Sulfadimethoxine, a sulfonamide antibiotic used to treat various infections. This compound is intended for research use only.
- Used as a tracer or internal standard for quantitative analysis
- Suitable for methods such as NMR, GC-MS, or LC-MS
- Isotope-labeled compound
- Internal standard for clinical mass spectrometry, food, pesticides, and veterinary medicine
- Stable isotope-labeled inhibitor for in vivo cell experiments
- Used in therapeutic drug monitoring (TDM)
Medchemexpress LLC D-Glucose-d12-1 | 89798-27-6 | 99.4% | 100 MG
D-Glucose-d12-1 is a deuterium-labeled D-Glucose, which is a monosaccharide essential for general metabolism and acts as a critical signaling molecule in cellular metabolic status and stress response. Deuteration can influence the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Bromhexine-d3 hydrochloride | 611-75-6 | 99.0% | 1 MG
Bromhexine-d3 (hydrochloride) is a deuterium-labeled Bromhexine (hydrochloride) that functions as a potent and specific TMPRSS2 protease inhibitor with an IC50 of 0.75 μM. It holds potential for preventing and managing SARS-CoV-2 infection and also acts as an autophagy agonist. Additionally, Bromhexine hydrochloride serves as a mucolytic cough suppressant, suggesting its utility in various respiratory conditions. This product is intended for research use only.
- Deuterium labeled Bromhexine (hydrochloride)
- Potent and specific TMPRSS2 protease inhibitor
- Can prevent and manage SARS-CoV-2 infection
- Autophagy agonist
- Mucolytic cough suppressant
- Used as a tracer or internal standard for quantitative analysis
Medchemexpress LLC 1,2-dimethyl-5-nitroimidazole-d3 | 64678-69-9 | MFCD09265282 | 99.9% | 144.15 | C5H4D3N3O2 | 10 MG
Dimetridazole-d3 is the deuterium-labeled analog of dimetridazole supplied as a solid analytical standard for research and quantitative analysis. It is used as an internal standard or isotopic tracer in mass spectrometry and other analytical workflows, providing well-defined isotopic composition and traceability.
- Isotope-labeled internal standard for mass spectrometry.
- High purity (≈99.9%) suitable for analytical use.
- Molecular weight 144.15 and formula C5H4D3N3O2.
- Provided as a 10 MG solid powder; other pack sizes available.
- Powder storage: -20 °C (3 years) or 4 °C (2 years); in solvent: -80 °C (6 months).
Medchemexpress LLC Calcitriol-d6 | 78782-99-7 | MFCD15071365 | 99.3% | 422.67 | C27H38D6O3 | 10 MG
Calcitriol-d6 is the deuterium-labeled form of calcitriol (1,25-dihydroxyvitamin D3) used as an isotopically labeled internal standard in research and quantitative analysis.
- Deuterium-labeled (d6) analog of calcitriol.
- Intended for use as an internal standard for LC-MS or GC-MS quantification.
- High chemical purity suitable for analytical applications.
- Molecular formula C27H38D6O3; molecular weight 422.67.