Isotopically Labeled Compounds
Medchemexpress LLC Theophylline-d6 | 117490-39-8 | 99.3% | 1 MG
Theophylline-d6 is the deuterium labeled Theophylline, a nonselective phosphodiesterase (PDE) inhibitor, adenosine receptor blocker, and histone deacetylase (HDAC) activator. Stable heavy isotopes are incorporated into drug molecules as tracers for quantitation during the drug development process, with deuteration potentially affecting pharmacokinetic and metabolic profiles.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stable isotope-labeled compound
- Used in internal standards for clinical mass spectrometry
- Deuterium (2H, D) stable isotope-labeled inhibitor
- Used in therapeutic drug monitoring (TDM)
![Revvity Health Sciences Inc Glucose, D-[6-<sup>3</sup>H(N)]-, 5mCi (185MBq)](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502812303.jpg-250.jpg)
Revvity Health Sciences Inc Glucose, D-[6-3H(N)]-, 5mCi (185MBq)
Glucose, D-[6-3H(N)]-, 5mCi (185MBq)
Medchemexpress LLC L-Aspartic acid-15N | 3715-16-0 | 134.10 | 50 MG
L-Aspartic acid-15N is the 15N-labeled version of L-Aspartic acid, an amino acid that can penetrate the blood-brain barrier. It is commonly used for preparing prodrugs to target colon and cecal tissues and in the study of inflammatory conditions.
- Used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Intended for research use only
Medchemexpress LLC Penicillin V-d5 | 1356837-87-0 | 99.5% | 1 MG
Penicillin V-d5 (Phenoxymethylpenicillin-d5) is the deuterium-labeled form of Penicillin V, an orally active antibiotic that inhibits the growth of Streptococci, C. difficile, and S. aureus. It is utilized in research for conditions such as otitis, sinusitis, pharyngitis, and tonsillitis.
- Deuterium-labeled Penicillin V for quantitative analysis.
- Inhibits the growth of Streptococci, C. difficile, and S. aureus.
- Suitable for research on otitis, sinusitis, pharyngitis, and tonsillitis.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration can influence pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Dxd-d5 (Exatecan-d5 derivative for ADC) | 1599440-33-1 | 98.9% | 498.51 | 1 ML
Dxd-d5 is a deuterium labeled Dxd, which is a potent DNA topoisomerase I inhibitor with an IC50 of 0.31 μM. It is used as a conjugated drug of HER2-targeting ADC (DS-8201a).
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration can influence the pharmacokinetic and metabolic profiles of drugs.
- Intended for research use only.
Medchemexpress LLC Creatine-d3 | 143827-19-4 | 99.5% | 134.15 | 25 MG
Creatine-d3 is a deuterium-labeled Creatine. Creatine, an endogenous amino acid derivative, plays an important role in cellular energy, particularly in muscle and brain.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes are incorporated into drug molecules, primarily as tracers for quantitation during drug development.
- Deuteration can affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Lusutrombopag-d13 | 1110766-97-6 | 98.6% | 604.63 | 1 MG
Lusutrombopag-d13 is deuterium labeled Lusutrombopag. Lusutrombopag is an orally bioavailable thrombopoietin (TPO) receptor agonist, used for treatment of chronic liver disease.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process.
- Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Phenindione-d5 | 70711-53-4 | 99.5% | 1 MG
Phenindione-d5 is deuterium labeled Phenindione, an anticoagulant that functions as a Vitamin K antagonist. It is for research use only and not sold to patients.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
![Revvity Health Sciences Inc Estradiol, [2,4,6,7-<sup>3</sup>H(N)]- 250µCi (9.25MBq)](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502810974.jpg-250.jpg)
Revvity Health Sciences Inc Estradiol, [2,4,6,7-3H(N)]- 250µCi (9.25MBq)
Estradiol, [2,4,6,7-3H(N)]- 250µCi (9.25MBq)
Cambridge Isotope Laboratories Bis(2-ethylhexyl)phthalate (ring-D4 98%) 0 1 g
Bis(2-ethylhexyl)phthalate (ring-D4 98%) 0 1 g
Medchemexpress LLC Phenol, 2,6-dibromo-d3 | 1219803-14-1 | MFCD03428106 | 25mg
2 6-Dibromophenol-d3 is the deuterium labeled 2 6-Dibromophenol[1] 2 6-Dibromophenol is an endogenous metabolite
Cayman Chemical 3-oxo Deoxycholic Acid, Purity: ≥95%, CAS: 4185-01-7, 10 mg
A secondary bile acid; a metabolite of deoxycholic acid in C. perfringens
![Medchemexpress LLC 3-[[2-[[(4-Carbamimidoylphenyl)amino]methyl]-1-(trideuteriomethyl)benzimidazole-5-carbonyl]-pyridin- | 1246817-44-6 | MFCD21363573 | 95.1% | 474.53 | C25H22D3N7O3 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000245661.png-250.jpg)
Medchemexpress LLC 3-[[2-[[(4-Carbamimidoylphenyl)amino]methyl]-1-(trideuteriomethyl)benzimidazole-5-carbonyl]-pyridin- | 1246817-44-6 | MFCD21363573 | 95.1% | 474.53 | C25H22D3N7O3 | 10 MG
Dabigatran-d3 is the deuterated (d3) stable-isotope analog of the direct thrombin inhibitor dabigatran. Supplied as an off-white to light-yellow solid, it is intended as an analytical reference standard or internal standard for quantitative mass-spectrometry assays. CAS 1246817-44-6; formula C25H22D3N7O3; MW 474.53; HPLC purity 95.14%.
- Deuterated internal standard for LC-MS quantitation.
- Off-white to light-yellow solid suitable for storage and handling.
- High isotopic labeling for accurate analyte normalization.
- Characterized molecular weight and formula for method development.
- Sufficient HPLC purity for analytical reference use.