Isotopically Labeled Compounds
Medchemexpress LLC Dioxybenzone-d3 | 131-53-3 | 1 MG
Dioxybenzone-d3 is deuterium labeled Dioxybenzone. Dioxybenzone (Benzophenone-8; UV-24) is an organic compound used to block UVB and short-wave UVA (ultraviolet) radiation. It has orally activity, exhibits estrogenic disrupting effects, and up-regulates inflammatory cytokines. This compound can be used for cancer, reproductive system, and inflammatory disease studies.
- Used as a tracer.
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes incorporated into drug molecules for quantitation during drug development.
- Deuteration can affect pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Diethyltoluamide-d7 | 1219799-37-7 | 98.5% | 1 MG
Diethyltoluamide-d7 is the deuterium labeled Diethyltoluamide. It is the most common active ingredient in insect repellents, providing protection against mosquitoes, ticks, fleas, chiggers, leeches, and many other biting insects. This product is for research use only.
- Deuterium labeled
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Piribedil-d8 | 1398044-45-5 | 99.8% | 1 MG
Piribedil-d8 is a deuterium-labeled analog of Piribedil, an antiparkinsonian agent known for its activity as a dopamine D2 and D3 agonist and α2-adrenoceptors antagonist. This compound serves as a valuable tracer and internal standard for quantitative analysis in various analytical techniques, including NMR, GC-MS, and LC-MS.
- Can be used as a tracer
- Functions as an internal standard for quantitative analysis
- Acts as a dopamine D2 and D3 agonist
- Serves as an α2-adrenoceptors antagonist
- Inhibits MLL1 methyltransferase activity
- Potential for research in Parkinson's disease, circulatory disorders, and cancers
Medchemexpress LLC Sulfathiazole-d4 | 1020719-89-4 | 99.9% | 5 MG
Sulfathiazole-d4 is a deuterium labeled Sulfathiazole. Sulfathiazole is an orally active, endocrine disruptor targeting the steroidogenic pathway, specifically enhancing the activity of CYP19 in human adrenal cancer cells (H295R) and upregulating the mRNA expression of CYP17, CYP19, and 3β-HSD. It increases the production of 17-estradiol (E2) and has endocrine disrupting effects on aquatic organisms such as the Japanese medaka fish.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Enhances the activity of CYP19 in human adrenal cancer cells (H295R)
- Upregulates the mRNA expression of CYP17, CYP19, and 3β-HSD
- Increases the production of 17-estradiol (E2)
- Has endocrine disrupting effects on aquatic organisms such as the Japanese medaka fish
Cayman Chemical 7-keto DeoxycholIc AcId 50mg
A metabolite of cholic acid; fecal levels are elevated in rats fed a diet supplemented with cholic acid compared with rats fed a control diet or a diet supplemented with cholesterol; hepatic levels are elevated in a mouse model of ethanol-induced alcoholic liver disease
Cayman Chemical IpronIdazole-d3 1mg
An internal standard for the quantification of ipronidazole by GC- or LC-MS
Cayman Chemical N-NItrosonrnIcotIn-d4 10mg
An internal standard for the quantification of N'-nitrosonornicotine by GC-or LC-MS
Cayman Chemical BaeocystIn-d4 1mg
An internal standard for the quantification of baeocystin by GC- or LC-MS; an intermediate in the biosynthesis of psilocybin; intended for research and forensic applications
Medchemexpress LLC Clotrimazole-d10 | 23593-75-1 | 97.51% | 354.90 | 10 MG
Clotrimazole-d10 | 23593-75-1 | 97.51% | 354.90 | 10 MG
Medchemexpress LLC Ribociclib-d8 | 2167898-24-8 | 99.2% | 440.59 | C23H25D8N8O | 10 MG
Ribociclib-d8 is the deuterium-labeled analogue of ribociclib supplied as an analytical reference standard for use in mass spectrometry and quantitative assays. It is intended for research use and provides a traceable internal standard for accurate quantitation in bioanalytical workflows.
- Deuterium-labeled internal standard for mass spectrometry.
- High purity suitable for analytical applications.
- Soluble in DMSO for convenient preparation of stock solutions.
- Molecular weight 440.59 and formula C23H25D8N8O for exact mass matching.
- Provided in a 10 MG quantity appropriate for method development and validation.
Medchemexpress LLC 1,2-dibromoethane-d4 | 22581-63-1 | MFCD00037499 | >99.0% | 191.88 | C2H4Br2D4 | 500 MG
1,2-Dibromoethane-d4 is a deuterium-labeled analog of 1,2-dibromoethane used as an isotopically labeled reagent and NMR solvent in research and analytical workflows.
- High isotopic enrichment (≥99.5%).
- Chemical purity >99.0%.
- Suitable for NMR spectroscopy and synthetic applications.
- Provides known chemical identifiers: CAS 22581-63-1, formula C2H4Br2D4, MW 191.88.
- Available as a 500 mg quantity for laboratory use.
Medchemexpress LLC Cobimetinib-d4 hydrochloride | 934660-93-2 | 99.3% | 1 MG
Cobimetinib-d4 hydrochloride is a deuterated labeled version of Cobimetinib, a potent, selective, and oral MEK1 inhibitor with an IC50 of 4.2 nM for MEK1. This compound is intended for research use only and not for sale to patients. Deuteration, the incorporation of stable heavy isotopes, is noted for its potential impact on the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Sigma Aldrich Fine Chemicals Biosciences Acetonitrile 15N 98 atom500MG
Acetonitrile 15N 98 atom500MG
Medchemexpress LLC Spermidine-d6 trihydrochloride | 98.0% | 260.67 g/mol | C7H16D6Cl3N3 | 5mg
Spermidine-d6 trihydrochloride is the deuterium labeled Spermidine-d6 (trihydrochloride) (HY-W709575)[1]
Cayman Chemical PItavastatIn lacton-d4 500ug
An internal standard for the quantification of pitavastatin lactone by GC- or LC-MS