Isotopically Labeled Compounds
Medchemexpress LLC Diclofenac-d4 | 153466-65-0 | C14H7D4Cl2NO2 | 5 MG
Diclofenac-d4 is a deuterium labeled form of Diclofenac, a potent and nonselective anti-inflammatory agent that acts as a COX inhibitor. It has been shown to induce apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade. Incorporating stable heavy isotopes like deuterium allows for its use as a tracer for quantitative analysis during drug development, potentially influencing pharmacokinetic and metabolic profiles.
- Deuterium labeled compound
- Potent and nonselective anti-inflammatory agent
- Acts as a COX inhibitor
- Induces apoptosis of neural stem cells
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Pyrene-d10 | 1718-52-1 | C16D10 | 50 MG
Pyrene-d10 is a deuterium labeled form of Pyrene, designed for research use only.
- Can be used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- For research applications only
Medchemexpress LLC 4H-1-Benzopyran-4-one, 2-(4,5-dihydroxyphenyl-2,3,6-d3)-3,5,7-trihydroxy- | 263711-79-1 | 96.4% | 305.25 | 2.5 MG
Quercetin-d3 is a deuterium labeled quercetin, a natural flavonoid that acts as a stimulator of recombinant SIRT1 and a PI3K inhibitor with IC50 values of 2.4 μM for PI3K γ, 3.0 μM for PI3K δ, and 5.4 μM for PI3K β. This compound is suitable for various quantitative analytical applications.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Xanthine-13C,15N2 | 1262670-81-4 | >98.0% | 155.09 | C413CH4N215N2O2 | 1 MG
Xanthine-13C,15N2 is a stable isotope-labeled xanthine supplied for research use as an internal standard, tracer, or for metabolic and mass spectrometry studies. It carries one 13C and two 15N labels and is provided as a dry powder suitable for analytical workflows.
- Contains 13C and 15N stable isotope labels.
- Suitable as an internal standard for LC-MS and tracer studies.
- High reported purity (≥98.0%).
- Soluble in water and 1 M NaOH under recommended conditions.
- Supplied in small milligram pack sizes for analytical applications.
Medchemexpress LLC 1,2-propylene-d6 carbonate | 202480-74-8 | MFCD00142486 | 98.7% | 108.13 | C4D6O3 | 100 MG
1,2-Propylene-d6 carbonate is the deuterium-labeled analogue of 1,2-propylene carbonate used as a stable-isotope tracer and internal standard in analytical techniques such as NMR, GC-MS, and LC-MS. It is provided with high isotopic and chemical purity for quantitative studies and metabolic tracing.
- High isotopic labeling (d6) for clear mass shifts.
- Suitable as an internal standard for NMR, GC-MS, and LC-MS.
- High chemical purity for reliable quantitative analysis.
- Available in small research-scale packaging for method development.
- Molecular weight 108.13; formula C4D6O3.
Medchemexpress LLC Aprepitant-d4 | 538.45 | C23H17D4F7N4O3 | 1MG
Aprepitant-d4 is the deuterium labeled Aprepitant[1]
Sigma Aldrich Fine Chemicals Biosciences Aldicarb-(N-methyl-13C,d3 carbamoyl-13C) >=98 atom %, >=98% (CP) | 1261170-75-5 | MFCD17677362 | 25MG
Aldicarb-(N-methyl-13C,d3 carbamoyl-13C) >=98 atom %, >=98% (CP) | Purity: >=98% (CP) | Mol Wt: 195.27 | 1261170-75-5 | MFCD17677362 | 25MG
Cayman Chemical DeoxycholIc ACD MaxSpec Sta
A quantitative analytical standard guaranteed to meet MaxSpec identity, purity, stability, and concentration specifications
Medchemexpress LLC Progesterone-d9 | 15775-74-3 | 323.52 | 1 MG
Progesterone-d9 is a deuterium-labeled version of Progesterone, a steroid hormone vital for regulating the menstrual cycle and pregnancy. Intended for research use only, it can be used as a tracer or an internal standard in quantitative analysis. Deuteration, the incorporation of stable heavy isotopes, can influence the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer in research applications
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Deuterium labeling can impact pharmacokinetic and metabolic profiles of drugs
- For research use only, not for patient use
Cayman Chemical L-threo-Sphingosine (d18:1), Purity: ≥98%, CAS: 25695-95-8, 5 mg
An analog of D-erythro-sphingosine; inhibits PKC in mixed micelle assays with 50% inhibition at 2.2 mol % making it a more potent inhibitor compared to D-erythro-sphingosine or other analogs of shorter alkyl chain length
Cambridge Isotope Laboratories Chloroform-D(D,99.8%)-Silver Foil, 865-49-6, MFCD00000827, 100 g
Chloroform-D(D,99.8%)-Silver Foil, 865-49-6, MFCD00000827, 100 g
Medchemexpress LLC L-Serine-13C3,15N | 202407-34-9 | 109.06 | 5 MG
L-Serine-13C3,15N is the 13C- and 15N-labeled L-Serine, a non-essential amino acid playing a central role in cellular proliferation. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules as tracers for quantitation during drug development. Deuteration can affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Phenol, 2-(methoxy-d3)- | 74495-69-5 | 127.16 | 25 MG
Guaiacol-d3 is the deuterium labeled Guaiacol. Guaiacol is a phenolic compound that inhibits LPS-stimulated COX-2 expression and NF-κB activation and exhibits anti-inflammatory activity.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process.
- Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.