Isotopically Labeled Compounds
Medchemexpress LLC D-glutamic acid-d5 | 14341-88-9 | MFCD08704921 | 99.9% | 152.16 g/mol | C5H4D5NO4 | 5 MG
D-Glutamic acid-d5 is a deuterium-labeled D-enantiomer of glutamic acid supplied as a high-purity, stable-isotope reference standard for analytical and research applications. It is intended for use in quantitative mass spectrometry, isotope-dilution experiments, metabolic tracing, and method development where an isotopically labeled D-amino acid standard is required.
- Stable isotope-labeled reference standard for quantitative analysis.
- High chemical and isotopic purity suitable for LC-MS/MS applications.
- Small, accurately measured solid packs for method development and validation.
- Validated for isotope-dilution and metabolic tracing studies.
- Documented purity and supporting COA available.
eMolecules 26690-80-2 | N-Boc-ethanolamine | Oakwood Chemical | MFCD00056657 | 161.201 | C7H15NO3 | 97.000 | CC(C)(C)OC(=O)NCCO | 500g | 537680035
N-Boc-ethanolamine | Oakwood Chemical | 26690-80-2 | MFCD00056657 | 161.201 | C7H15NO3 | 97.000 | CC(C)(C)OC(=O)NCCO | 500g | 537680035
Medchemexpress LLC Deoxycholic acid | 83-44-3 | 392.57 | 500 MG
Deoxycholic acid (cholanoic acid), a bile acid, is a by-product of intestinal metabolism that activates the G protein-coupled bile acid receptor TGR5. It is for research use only and not sold to patients.
- Activates the G protein-coupled bile acid receptor TGR5.
- Functions as a microbial metabolite.
- Functions as a human endogenous metabolite.
- In vitro, it induces production of gastric cancer cell line MGC803 resistant to acidified bile acids, enhancing survival and proliferation activity under bile acid stress.
- DCA-induced resistant cells show altered morphology, elevated telomerase activity, improved cell viability, and reduced apoptosis compared to normal MGC803 cells.
Medchemexpress LLC Hydrocortisone-d3 | 115699-92-8 | 365.48 | 1 MG
Hydrocortisone-d3 is the deuterium labeled Hydrocortisone, a steroid hormone or glucocorticoid secreted by the adrenal cortex. It can be used as a tracer or an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process.
- Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Alogliptin-13C,d3 benzoate | 1246817-18-4 | 98.8% | 1 MG
Alogliptin-13C,d3 benzoate is a stable isotope-labeled compound, primarily used as a tracer or an internal standard for quantitative analysis using techniques like NMR, GC-MS, or LC-MS. It is a PEG-based PROTAC linker that can be utilized in the synthesis of PROTACs, which are molecules designed to exploit the intracellular ubiquitin-proteasome system for selective degradation of target proteins.
- Application as a tracer: Can be used in studies to track metabolic pathways or drug distribution.
- Internal standard for quantitative analysis: Ideal for precise measurement in analytical methods such as NMR, GC-MS, or LC-MS due to its isotope labeling.
- PROTAC linker: Serves as a linker in the construction of PROTACs, which are bifunctional molecules that induce targeted protein degradation.
- Research use only: This product is intended for research and development purposes and not for sale to patients.
Medchemexpress LLC Arabinose-d | 77583-92-7 | 5 MG
Arabinose-d is a deuterium-labeled Arabinose, an endogenous metabolite. Stable heavy isotopes like hydrogen, carbon, and other elements are incorporated into drug molecules for use as tracers in quantifying during drug development. Deuteration is of interest due to its potential impact on the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Hordenine-d6 | 1346598-66-0 | 98.03% | 171.27 | 1 MG
Hordenine-d6 is a deuterium-labeled variant of Hordenine, an alkaloid naturally occurring in plants. The unlabeled form of Hordenine has been shown to inhibit melanogenesis by suppressing the production of cyclic adenosine monophosphate (cAMP). Deuterium-labeled compounds incorporate stable heavy isotopes of elements like hydrogen and carbon into drug molecules. This labeling technique is primarily used as a tracer for quantitative analysis during drug development, and it has garnered attention for its potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer in research applications.
- Serves as an internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS.
- Incorporation of stable heavy isotopes can affect the pharmacokinetic and metabolic profiles of compounds.
- It is a deuterium labeled compound.
Medchemexpress LLC γ-Glu-(Phe-13C9,15N) TFA | 99.7% | 418.25 | C713C9H19F3N15NO7 | 5 MG
γ-Glu-(Phe-13C9,15N) TFA is an isotopically labeled γ-glutamylphenylalanine supplied as the trifluoroacetate salt for use as an internal standard or tracer in analytical and metabolomics workflows. The phenylalanine residue is labeled with 13C9 and the amide nitrogen with 15N, enabling precise quantitation by mass spectrometry and NMR.
- Isotopically labeled phenylalanine residue (13C9) and 15N-labeled amide nitrogen.
- Supplied as the trifluoroacetate (TFA) salt for stability and handling.
- High purity as reported by batch COA (99.74% LCMS).
- Molecular weight approximately 418.25 Da.
- Suitable as internal standard, tracer, or reference in metabolomics and analytical methods.
- Available in small research quantities (for example, 5 mg) for analytical applications.
Medchemexpress LLC D-Arabinose-1-C-d | 77583-92-7 | 25 MG
Arabinose-d is a deuterium-labeled form of Arabinose, which is an endogenous metabolite. This compound is intended for research use only and serves as a tracer or internal standard for quantitative analysis.
- Used as a tracer
- Used as an internal standard for quantitative analysis via techniques such as NMR, GC-MS, or LC-MS
- Deuteration may influence pharmacokinetic and metabolic profiles of drugs
- Incorporates stable heavy isotopes for quantitation during drug development
Cayman Chemical Sulfamethoxazole-d4 10mg
An internal standard for the quantification of sulfamethoxazole by GC- or LC-MS
Sigma Aldrich Fine Chemicals Biosciences Succinic acid-2,2,3,3-d4 98 atom % D | 14493-42-6 | MFCD00002791 | 5G
Succinic acid-2,2,3,3-d4 98 atom % D | Purity: 99% (CP) | Mol Wt: 122.11 | 14493-42-6 | MFCD00002791 | 5G
Sigma Aldrich Fine Chemicals Biosciences Succinic acid-2,2,3,3-d4 98 atom % D | 14493-42-6 | MFCD00002791 | 1G
Succinic acid-2,2,3,3-d4 98 atom % D | Purity: 99% (CP) | Mol Wt: 122.11 | 14493-42-6 | MFCD00002791 | 1G