Isotopically Labeled Compounds
Medchemexpress LLC Vortioxetine-d8 hydrobromide | 960203-27-4 | C18H15D8BrN2S | 1 MG
Vortioxetine-d8 hydrobromide, also known as Lu AA 21004-d8 hydrobromide, is a deuterated form of Vortioxetine. Vortioxetine acts as an antagonist of 5-HT3A and 5-HT7 receptors, and an inhibitor of the 5-hydroxytryptamine transporter (SERT). It also functions as a 5-HT1A agonist and a partial 5-HT1B agonist.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Targets 5-HT1A receptor
- Targets 5-HT1B receptor
- Targets 5-HT3A receptor
- Targets 5-HT7 receptor
Medchemexpress LLC Empagliflozin-d4 | 2749293-95-4 | C23H23D4ClO7 | 5 MG
Empagliflozin-d4 is deuterium labeled Empagliflozin. Empagliflozin is a selective sodium glucose cotransporter-2 (SGLT-2) inhibitor with an IC50 of 3.1 nM for human SGLT-2.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Umifenovir-d6 (hydrochloride) | 2928218-29-3 | 519.91 | 500 UG
Umifenovir-d6 (hydrochloride) is a deuterated form of Umifenovir hydrochloride, primarily used as a laboratory chemical and in the manufacture of substances. It is stable under recommended storage conditions.
- Solid appearance
- Stable under recommended storage conditions
- Recommended storage at -20°C, sealed, and away from moisture
- For research use only
Medchemexpress LLC N-Carbamimidoyl-N-(methyl-d3)glycine-2,2-d2 hydrate | 99.9% | 154.18 g/mol | C4H6D5N3O3 | 10 MG
Creatine-d5 monohydrate is a deuterium-labeled isotopic standard of creatine monohydrate designed for research and analytical applications. It is used as an internal standard in mass spectrometry and other bioanalytical assays to improve quantitation accuracy and traceability in metabolic and pharmacokinetic studies.
- High isotopic enrichment for reliable mass-differentiation.
- High chemical purity (99.93%).
- Molecular formula: C4H6D5N3O3.
- Molecular weight: 154.18 g/mol.
- Provided with certificate of analysis and datasheet.
- Available in small pack sizes suitable for analytical use.
- Suitable as an internal standard for LC-MS applications.
Medchemexpress LLC Guanidinoacetic acid-d2 | 1173020-63-7 | 99.9% | 119.12 | C3H5D2N3O2 | 100 MG
Glycocyamine-d2 (guanidinoacetic acid-d2) is the deuterium-labeled form of glycocyamine used as a stable isotope reagent and internal standard for analytical assays and metabolic tracing. It is provided at high isotopic and chemical purity for accurate quantitation in LC-MS/MS and related methods.
- Deuterium-labeled (d2) for reliable isotope tracing.
- High purity (99.90%) suitable for quantitative analysis.
- Molecular weight 119.12 and formula C3H5D2N3O2 for reference.
- Available in small package sizes for analytical workflows.
- Applicable as an internal standard in LC-MS/MS and metabolic studies.
Medchemexpress LLC Fumaric acid-13C2,d2 | 100858-52-4 | 98.0% | 120.07 g/mol | C213C2H2D2O4 | 1 MG
Fumaric acid-13C2,d2 is a stable isotope-labeled fumaric acid where two carbon atoms are 13C-labeled and two hydrogen atoms are deuterated. It is provided as a high-purity solid for use as an analytical standard, tracer, or reagent in metabolic and mass spectrometry studies, and is available in small milligram quantities for sensitive experiments.
- Stable isotope labeling for tracer studies and metabolic experiments.
- High purity suitable for analytical and mass spectrometry applications.
- Available in small quantities for sensitive assays and method development.
- Solid, white to off-white appearance for straightforward handling and storage.
- Provided with product datasheet and safety data sheet for laboratory use.
Medchemexpress LLC N-methylacetamide-d6 | 3669-73-6 | MFCD01073934 | 98.6% | 79.13 g/mol | C3HD6NO | 5 MG
N-methylacetamide-d6 is the deuterium-labeled analogue of N-methylacetamide, provided as a high-purity stable-isotope reagent for analytical and research applications. It is intended for use as an internal standard, NMR reference, and tracer in chemical and biochemical studies, and is supplied with supporting documentation for quality and safety.
- Deuterium labeled for isotope tracing and analytical standards.
- High purity suitable for mass spectrometry and NMR applications.
- Available in small, precise pack sizes for analytical workflows.
- Molecular weight 79.13 g/mol; chemical formula C3HD6NO.
- Provided with datasheet, certificate of analysis, and safety data sheet.
Medchemexpress LLC D-ribose-13C | 70849-24-0 | MFCD00064325 | 99.9% | 151.12 g/mol | (13C)C4H10O5 | 100 MG
D-ribose-13C is a stable isotope-labeled form of D-ribose supplied as a white to off-white solid for laboratory research. It is used as a positional tracer in metabolic and biochemical studies to follow ribose incorporation and quantify metabolic flux by analytical techniques such as NMR and mass spectrometry. The material is high purity and packaged in small quantities for research-scale experiments.
- 13C-labeled at carbon-1 for positional tracing.
- High purity suitable for analytical applications.
- White to off-white solid form for easy handling and storage.
- Compatible with NMR and mass spectrometry workflows.
- Available in small package sizes for research-scale experiments.
- Intended for research use only; not for human consumption.
Medchemexpress LLC Febuxostat-d7 | 1285539-74-3 | 99.1% | C16H9D7N2O3S | 1 MG
Febuxostat-d7 is a deuterium labeled form of Febuxostat, a selective xanthine oxidase inhibitor with a Ki of 0.6 nM. It serves as a tracer and an internal standard for quantitative analysis. Deuterated compounds are used as tracers for quantitation during drug development and can affect pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Deuterium labeled Febuxostat
- Selective xanthine oxidase inhibitor with a Ki of 0.6 nM
- For research use only
Medchemexpress LLC Fumaric acid-d4 | 194160-45-7 | MFCD00190450 | 98.0% | 120.10 g·mol^-1 | C4D4O4 | 50 MG
Fumaric acid-d4 is the deuterium-labeled analogue of fumaric acid supplied as a stable isotope standard for analytical and research use. It is intended for metabolomics, tracer studies, and mass spectrometry assays requiring isotopically labeled internal standards, and supports investigations into fumarase deficiency and oncometabolite pathways.
- Deuterium-labeled internal standard for analytical assays.
- Molecular formula C4D4O4, molecular weight 120.10 g·mol^-1.
- High isotopic enrichment suitable for mass spectrometry.
- Available in small pack sizes appropriate for research workflows.
- Used in metabolomics, tracer, and biochemical pathway studies.
Medchemexpress LLC Istradefylline-13C,d3 | 2749234-46-4 | 98.3% | 388.44 | 50 MG
Istradefylline-13C,d3 is the 13C- and deuterium labeled Istradefylline. It is a very potent, selective and orally active adenosine A2A receptor antagonist with Ki of 2.2 nM in experimental models of Parkinson's disease.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Tipranavir-d7 | 174484-41-4 | C31H26D7F3N2O5S | 5 MG
Tipranavir-d7 is a deuterated form of Tipranavir. Tipranavir is known to inhibit the enzymatic activity and dimerization of HIV-1 protease. It demonstrates potent activity against multi-protease inhibitor (PI)-resistant HIV-1 isolates, with IC50s ranging from 66-410 nM. Additionally, Tipranavir has been shown to inhibit SARS-CoV-2 3CLpro activity.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Exerts potent activity against a wide spectrum of wild-type and multi-PI-resistant HIV-1 variants.
- Inhibits the enzymatic activity of HIV-1 protease.
- Blocks the dimerization of protease subunits.
Medchemexpress LLC 1-dodecanol-d25 | 160776-83-0 | MFCD00144869 | >98.0% | 211.49 g/mol | C12HD25O | 25mg
1-Dodecanol-d25 is the deuterium labeled 1-Dodecanol 1-Dodecanol is an endogenous metabolite
Medchemexpress LLC Ethylene glycol-d4 (1,2-ethanediol-d4) | 2219-51-4 | MFCD00144289 | 99.8% | 66.09 g/mol | C2H2D4O2 | 500mg
Ethylene glycol-d4 is the deuterium labeled Ethylene glycol[1]
Medchemexpress LLC Sodium phosphate dibasic-d2 | 107632-22-4 | 99.0% | 142.97 g·mol⁻1 | DNa2O4P | 5mg
Phosphate dibasic-d2 (sodium) is the deuterium labeled Sodium phosphate dibasic[1]