RNAi Screening Libraries
STEMCELL Technologies ArciTect High-Fidelity DNA Pol, 500 Reactions
Polymerase buffers and dNTPs for high-fidelity PCR amplification
Cayman Chemical ImunoOncology Screeng LIb 50uL
An antibiotic active against Gram positive and Gram negative bacteria at 255 Ug/ml inhibits bacterial protein synthesis (EC50 0 4 UM in E coli) increases EF-Tu-associated GTPase activity (EC50 6 UM in E coli)
Cayman Chemical Rat ndrogen Receptr Reporte 96
A diacylglycerol has been used for the determination of the diacylglycerol fatty acyl chain properties that activate ARF1 GAP
Cayman Chemical ScavengR Receptr B2CD36 Ex 1mg
A K-opioid receptor agonist activates KOR in HEK293 cells expressing the human receptor (EC50 0 16 nM in a transactivation assay) inhibits forskolin-induced cAMP production in R1 G1 cells (EC50 0 048 nM) selective for KOR over MOR (EC50 1 UM in a transactivation assay) reduces acetic acid-induced writhing as well as GNTI-induced scratching behavior in mice (ED50s 0 07 and 0 05 mg/kg respectively)
Cayman Chemical TrnsfRrIn Receptr ProteIn 50uL
A photosensitizer induces cell death in RIF-1 cells when used in combination with PDT at 0.06 and 1 UM induces IL-1 receptor internalization and NF-KB activation following light exposure in HCT116 cells
Cayman Chemical Rat LIvR X Receptr Beta Rep 96
An amine-reactive fluorescent protein-labeling agent abs/em UV/400-460 nm respectively contains an N-hydroxysuccinimide ester that reacts with lysine residues to form photostable amide links has commonly been used in multiplex immunophenotyping applications
Cayman Chemical Humn Growth Hormon Receptr 384
A water-soluble and cell-permeable tetrazolium dye upon enzymatic cleavage formazan is released which can be quantified by colorimetric detection at 450 nm as a measure of cell viability
Cayman Chemical Strogen Receptr a & C re 100uL
A derivative of DL-homocysteine inhibits the growth of B. campestris L. sativa and E. utilis roots at 50 UM decreases the maximum rate of left ventricular developed pressure systolic left ventricular pressure and coronary flow in isolated rat hearts at 10 UM induces arteriosclerotic plaque formation in rabbits at 30 mg/kg for eight weeks has also been used as a precursor in the synthesis of thiolactone-containing monomers for use in polymer-based formaldehyde-scavenging coatings
Cayman Chemical MelnocortIn4 Receptr Repor 1ea
An MC4R antagonist selectively inhibits [Nle4D-Phe7]-a-MSH binding to recombinant human MC4R over MC1R and MC3R (IC50s 11.63 >10000 and 1115 nM respectively) inhibits a-MSH-induced cAMP production in COS-1 cells expressing human MC4R from 0.1-100 UM reduces stress-induced decreases in the time spent in the light area of the light/dark exploration test in mice reverses restraint stress-induced decreases in food intake in rats
Cayman Chemical OrexIn 1 Receptr ReporTR1ea
A linker molecule has been used to conjUGate SN-38 to phlorizin or phloretin to increase the selectivity of SN-38 for cancer cells
Cayman Chemical EP Receptr asy Prostaglnd 20uL
An ionizable cationic lipid (pKa 6.39) has been used in the generation of LNPs for siRNA delivery in vitro and in vivo LNPs containing O12-D3-I3 and encapsulating ferrocene and siRNA targeting Nrf2 or system xc- cystine/glutamate transporter decrease viability of HepG2 cells LNPs containing O12-D3-I3 and an mRNA reporter selectively accumulate in the tumor and liver over the lungs kidneys spleen and heart in mice LNPs containing O12-D3-I3 and encapsulating ferrocene and siRNA targeting Nrf2 or system xc- cystine/glutamate transporter reduce tumor growth and volume in an MCF-7 breast cancer mouse xenograft model LNPs containing O12-D3-I3 and encapsulating siRNA targeting Factor VII decrease hepatocyte Factor VII mRNA levels in mice
Cayman Chemical Mouse LIvR X Receptr Beta R 96
An amine-reactive fluorescent protein-labeling agent abs/em UV/400-460 nm respectively contains an N-hydroxysuccinimide ester that reacts with lysine residues to form photostable amide links has commonly been used in multiplex immunophenotyping applications
Cayman Chemical Humn RetInoIc ACD Receptr 96
A substituted cathinone that is an analog to ethcathinone differing by having propyl rather than methyl at the a position intended for forensic and research purposes.
Cayman Chemical Humn RetInoIc ACD Receptr 96
A substituted cathinone that is an analog to ethcathinone differing by having propyl rather than methyl at the a position intended for forensic and research purposes.