Lectins
Cayman Chemical Cholesteryl Eicosapentaenoate
A potent and selective VEGFR2 inhibitor selective for VEGFR2 over VEGFR1 PDGFRB FGFR1 EGFR and ErbB2 at concentrations greater than 50 UM inhibits VEGF-A-stimulated cell proliferation of HUVECs (IC50 8 nM)
Sigma Organic Chemistry SAM Formation reagent for biotin terminated monolayer on gold surface | 1SET
SAM Formation reagent for biotin terminated monolayer on gold surface, 1SET
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UNSPSC Code: 12352103
Storage: 2-8C
Vector Laboratories Vicia Villosa Lectin (VVL VVA) Agarose Bound 2 ml
Vicia villosa lectin (VVL) includes a family of tetrameric glycoproteins consisting of combinations of A and B subunits, though the dominant isolectins in our preparations appear to be B subunit-rich. VVL recognizes α- or β-linked terminal N-acetylgalactosamine, especially a single α-N-acetylgalactosamine residue linked to serine or threonine in a polypeptide (the Tn antigen). Binding may also require specific amino acid sequences at the receptor site of glycosylation. This agarose-bound VVL is prepared using affinity-purified lectin and heat stable, cross-linked 4% agarose beads. The attachment of the lectin through a hydrophilic spacer arm to the beads is carefully controlled to preserve the activity and minimize conformational changes to the bound lectins. The recommended inhibiting/eluting sugar is 200 mM N-acetylgalactosamine.
Vector Laboratories Erythrina Cristagalli Lectin (ECL, ECA) Unconjugated 10 mg
Erythrina cristagalli lectin (ECL, ECA) binds a carbohydrate structure frequently found in mammalian membrane and serum glycoproteins. Sialic acid substitution on this structure prevents binding, and this specificity offers an opportunity to use ECL to isolate or fractionate glycoproteins. ECL has been useful for the isolation of human natural killer (NK) cells using a negative selection panning technique (protocol available). Human NK cells lack accessible carbohydrate structures required for binding ECL and, unlike other mononuclear cells, do not adhere to ECL-coated culture dishes. Since this procedure involves a negative selection panning technique, a high recovery of viable NK cells can be obtained. The adherent cells can also be recovered by incubation in galactose or lactose.
Vector Laboratories Lens Culinaris Agglutinin (LCA, LcH) Unconjugated 10 mg
Lens culinaris agglutinin (LCA) contains two subunits of 17 kDa and two of 8 kDa. It has a narrower specificity than ConA because it recognizes sequences containing α-linked mannose residues and other sugars as part of the receptor structure. An α-linked fucose attached to the N-acetylchitobiose of the core oligosaccharide enhances affinity. The narrower specificity allows subfractionation of glycoproteins and -peptides after initial isolation with Con A. LCA prevents skin allograft rejection and can purify numerous glycoproteins, including immunoglobulins, histocompatibility antigens, and α2-macroglobulin. This unconjugated form is supplied as a solution preserved with sodium azide. The recommended inhibiting/eluting sugar is a mixture of 200 mM α-methylmannoside/200 mM α-methylglucoside.
Vector Laboratories Aleuria Aurantia Lectin (AAL) Agarose Bound 2 ml
Aleuria Aurantia Lectin (AAL) is a dimer of two identical subunits of about 36 kDa each. Unlike Ulex europaeus and Lotus tetragonolobus lectins which prefer (a -1,2) linked fucose residues, Aleuria aurantia lectin binds preferentially to fucose linked (a -1,6) to N-acetylglucosamine or to fucose linked (a -1,3) to N-acetyllactosamine related structures. AAL also reversibly binds fucose attached to nucleic acids. Agarose Bound Aleuria Aurantia Lectin is prepared using affinity-purified lectin and heat stable, cross-linked 4% agarose beads. The attachment of the lectins through a hydrophilic spacer arm to the beads is carefully controlled to preserve lectin activity and minimize conformational changes of the bound lectins. The recommended inhibiting/eluting sugar is 100 mM L-fucose.
Vector Laboratories Lotus Tetragonolobus Lectin (LTL) Biotinylated 2 mg
Lotus tetragonolobus lectin (LTL) encompasses a family of closely related glycoproteins with similar specificities toward α-linked L-fucose-containing oligosaccharides. Although many of the binding properties of Lotus lectin are similar to those of Ulex europaeus lectin I (UEL I), the binding affinities and some specificities for oligosaccharides are significantly different between these fucose-specific lectins. This conjugate features a ratio of biotin to lectin protein that provides optimal avidin/streptavidin and lectin binding activity. Supplied essentially free of unconjugated biotins, it is preserved with sodium azide.
BIORTUS USA INC Human RNF4, biotinylated Protein, 100UG
Gene Name: RNF4. Uniprot: P78317. Construct:biotinylated-GG-RNF4(G120-I190 end). Expression Host: E. coli. Purity: 90%.
BIORTUS USA INC Human KRas4B Protein, biotinylated, 100UG
Gene Name: KRAS. Uniprot: P01116. Construct: biotinylated-Avi-KRas4B(T2-M188 end), GMPPNP loaded. Expression Host: E. coli. Purity: 95%.