Cell Culture Media, Supplements, and Reagents
Medchemexpress LLC HDAC-IN-4 | 1252003-13-6 | 50 MG
HDAC-IN-4 is a selective inhibitor targeting both HDAC6 and HDAC10, exhibiting pIC50 values of 7.2 and 6.8 in BRET assays, respectively. This compound has demonstrated antitumoral activity.
- Selective HDAC6 and HDAC10 inhibitor
- Exhibits antitumoral activity
- Used in BRET assays
![Research Products International Corp 17-AAG [17(Allyamino)-17-demothoxygeldanamycin], 500 Micrograms](https://assets.fishersci.com/TFS-Assets/CCG/product-images/VN00006095-A20045-0.0005.JPG-250.jpg)
Research Products International Corp 17-AAG [17(Allyamino)-17-demothoxygeldanamycin], 500 Micrograms
17-AAG (17-Allylamino-17-demethoxygeldanamycin) is a synthetic derivative of geldanamycin. Like geldanamycin, 17-AAG is recognized for its role as an inhibitor of heat shock protein 90 (Hsp90), a molecular chaperone involved in protein folding and stabilization.
It is often used as a tool to study Hsp90-dependent processes. By inhibiting Hsp90, 17-AAG impacts the stability and function of various client proteins, many of which are involved in critical cellular processes, including signal transduction and cell cycle regulation.
Researchers use 17-AAG to explore the molecular mechanisms of Hsp90 inhibition, with potential applications in understanding cancer biology and developing therapeutic strategies.
Gold Biotechnology Inc Streptomycin Sulfate 100 g
Streptomycin is an aminoglycoside antibiotic primarily effective against gram-negative bacteria and Mycobacterium species It is commonly used in cell culture media to prevent bacterial contamination It has also been used to precipitate nucleic acids during protein purification techniques and to study mechanisms of Streptomycin resistance
Gold Biotechnology Inc Chloramphenicol USP Grade
Chloramphenicol also known as chlornitromycin is a broad-spectrum bacteriostatic antibiotic derived from Streptomyces venezuelae It is effective against several gram-positive and gram-negative bacteria and commonly used in researching protein synthesis and to select for chloramphenicol-resistant transformed cells or the bacterial CAT /em gene Chloramphenicol functions by binding the 50s ribosomal subunit and inhibiting synthesis of proteins by blocking aminoacyl-tRNA from attaching to the A site
Research Products International Corp Cefotaxime, Sodium Salt, 1 Gram
Cefotaxime Sodium Salt is a third-generation cephalosporin antibiotic. Cefotaxime, as a cephalosporin, exerts its antibacterial effects by inhibiting bacterial cell wall synthesis. It does this by binding to penicillin-binding proteins (PBPs), disrupting the final step of peptidoglycan synthesis in the bacterial cell wall. This interference leads to structural instability and eventual lysis of the bacterial cell.
Cefotaxime sodium salt is frequently used as a selective agent in culture media to isolate bacteria that are sensitive to this antibiotic. Its inclusion in culture medium allows for the specific growth of bacteria lacking resistance to cefotaxime.
Medchemexpress LLC Lomeguatrib | 192441-08-0 | 99.8% | 326.17 | 100 MG
Lomeguatrib is an O6-methylguanine-DNA methyltransferase (MGMT) inhibitor. It exhibits an IC50 of 9 nM in cell-free assays and 6 nM in MCF-7 cells.
- Acts as an O6-methylguanine-DNA methyltransferase (MGMT) inhibitor.
- Shows an IC50 of 9 nM in cell-free assays.
- Exhibits an IC50 of 6 nM in MCF-7 cells.
- Increases the growth inhibitory effects of temozolomide in MCF-7 cells.
- Completely inactivates MGMT within 2 hours at 20 mg/kg i.p.
Medchemexpress LLC Menin-MLL inhibitor 19 | 2360487-93-8 | 98.1% | 645.70 | 100 MG
Menin-MLL inhibitor 19 is a potent exo-aza spiro inhibitor that targets the menin-mll interaction. This compound is suitable for research into various diseases, including cancer, myelodysplastic syndrome (MDS), and diabetes. It is intended for research use only and not for patient treatment. The product appears as a solid, white to light yellow in color.
- Potent exo-aza spiro inhibitor of menin-mll interaction
- Suitable for research on cancer, myelodysplastic syndrome (MDS), and diabetes
- Appears as a solid
- White to light yellow color
ILEX LIFE SCIENCES LLC AMPHOTERICIN B 250UG/ML 100ML
PAN-Biotech Amphotericin B for cell culture (Fungizone generic), 250 ug/ml (100 ml). DESCRIPTION: PAN-Biotech Amphotericin B (250 ug/ml) is a generic version of Fungizone that is used in cell culture applications. Amphotericin B is an antifungal agent produced by Streptomyces sp.. Amphotericin B increases fungal plasma membrane permeability by binding to sterols, thereby protecting cell cultures from contamination by yeast and multicellular fungi. APPLICATION: Amphotericin B is often used as an antifungal, anti-yeast and anti-mold agent to prevent fungal contamination of cell cultures. The commonly recommended working concentration ranges from 0.25-2.5 ug/mL (1-10 mL/L). LIQUID/POWDER: Liquid. STERILE: Yes. STORAGE TEMP.: -20°C. MANUFACTURER: PAN-Biotech GmbH. COUNTRY OF ORIGIN: Germany. USAGE: This product is intended for Laboratory Research Use Only. Not for use in diagnostic or therapeutic procedures.
Takara Bio Aureobasidin A, 10mg
Aureobasidin A (AbA) is a cyclic depsipeptide antibiotic, isolated from the filamentous fungus Aureobasidium pullulans R106, which is toxic to yeast at low concentrations (0.10.5 g/ml). Sensitive species include Saccharomyces cerevisiae, Schizosaccharomyces pombe, Candida glabrata, Aspergillus nidulans and A. niger. AbA inhibits a yeast enzyme, inositol phosphorylceramide (IPC) synthase, which is expressed from the AUR1 gene. Expression of a mutant gene, AUR1-C, in transformed yeast confers resistance to the drug.
Research Products International Corp Hygromycin B Liquid, 1 Vial
Hygromycin B is an antibiotic commonly used in molecular biology and biotechnology. It is derived from the bacterium Streptomyces hygroscopicus and acts as a selective agent in cell culture.
Often used for the selection of cells that have been genetically engineered to express a hygromycin resistance gene. This gene is typically included in plasmids or vectors used in molecular cloning and genetic engineering. Cells that successfully integrate and express the hygromycin resistance gene become resistant to the inhibitory effects of Hygromycin B.
Hygromycin B is available in various forms, including a liquid solution. Liquid solution is commonly used to establish and maintain stable cell lines, especially during the development of transgenic cells and the generation of genetically modified organisms. The liquid form allows for easy incorporation into cell culture media.
Medchemexpress LLC HY-119367 10mg Medchemexpress, ODM-203 CAS:1430723-35-5 Purity:>98%
Medchemexpress, HY-119367 10mg ODM-203 CAS:1430723-35-5 ODM-203 is a potent FGFR and VEGFR families inhibitor with IC50s of 11, 16, 6, 35 nM towards recombinant FGFR1, FGFR2, FGFR3 and FGFR4 as well as 26, 9, 5 nM towards VEGFR1, VEGFR2 and VEGFR3, respectively. ODM-203 exhibits strong anti-tumor activity and induces anti-tumor immunity. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-16715 5mg Medchemexpress, Acumapimod CAS:836683-15-9 Purity:>98%
Medchemexpress, HY-16715 5mg Acumapimod CAS:836683-15-9 Acumapimod (BCT197) is an orally active p38 MAP kinase inhibitor, with an IC50 of less than 1 μM for p38α. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-17042A 100mg Medchemexpress, Cetirizine (dihydrochloride) CAS:83881-52-1 Purity:>98%
Medchemexpress, HY-17042A 100mg Cetirizine (dihydrochloride) CAS:83881-52-1 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Frontier Specialty Chemicals Doxycycline hydrochloride, 10592-13-9, MFCD03427564, 1g
This item has a minimum qty of 8 per supplier requirements.
Molecular Formula C22H25ClN2O8, Purity 98%, Molecular Weight 480.90
![Research Products International Corp Timentin [Ticarcillin Disodium Salt/Potassium Cavulanate Mixture 15:1 Ratio], 5 Grams](https://assets.fishersci.com/TFS-Assets/CCG/product-images/VN00006095-T36000-5.0.JPG-250.jpg)
Research Products International Corp Timentin [Ticarcillin Disodium Salt/Potassium Cavulanate Mixture 15:1 Ratio], 5 Grams
Timentin contains two antibiotics: ticarcillin (a penicillin) and clavulanate potassium (a beta-lactamase inhibitor). The combination of ticarcillin and clavulanate enhances the spectrum of antibacterial activity by protecting ticarcillin from degradation by certain bacterial enzymes.
Ticarcillin inhibits bacterial cell wall synthesis, disrupting the integrity of the bacterial cell wall and leading to bacterial cell lysis. Clavulanate potassium works by inhibiting beta-lactamases, enzymes produced by bacteria that can inactivate beta-lactam antibiotics, such as ticarcillin. This combination is effective against a broad spectrum of bacteria, including those producing beta-lactamases.