Medchemexpress, HY-10009 5mg Semagacestat CAS:425386-60-3 Semagacestat is a γ-secretase inhibitor, inhibits β-amyloid ( Aβ42 ), Aβ38 and Aβ40 with IC 50 of 10.9, 12 and 12.1 nM, respectively; also inhibits Notch signaling with IC 50 of 14.1 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.