Cell Culture Media, Supplements, and Reagents
eMolecules 1020719-62-3 | Medchem Express | Pirfenidone-d5 | 1mg | 716993897 | HY-B0673S | MFCD07369537 | 190.257 | C12H11NO
Ambeed | Fmoc-Val-Cl | 250mg | 601096053 | A614270 | 103321-53-5 | MFCD00235840 | 357.830 | C20H20ClNO3
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eMolecules Building Block Tool
eMolecules 1336935-03-5 | rac 1-Oleoyl-2-linoleoyl-3-chloropropanediol | Broadpharm637.430 | C39H69ClO4 | 0.000 | CCCCCCCC\C=C/CCCCCCCC(=O)OCC(CCl)OC(=O)CCCCCCC\C=C/C\C=C/CCCCC | 25mg | 784455268
rac 1-Oleoyl-2-linoleoyl-3-chloropropanediol | Broadpharm | 1336935-03-5637.430 | C39H69ClO4 | 0.000 | CCCCCCCC\C=C/CCCCCCCC(=O)OCC(CCl)OC(=O)CCCCCCC\C=C/C\C=C/CCCCC | 25mg | 784455268
Amsbio LLC Recombinant Laminin iMatrix-221 (2 tubes x 175μg)
iMatrix-221 is a recombinant human laminin-221 E8 fragment expressed by CHO-S cells. Laminin-221 is abundant in basement membranes surrounding cardiac and skeletal muscle cells, and binds to the cell membrane receptor integrin 7X21. iMatrix-221 can also be used together with AMSBIO's StemFit cell culture media and CELLBANKER cryopreservation series as part of an expanded Stem Cell Synergy solution for ES/iPS cell cultures.
Medchemexpress LLC Miglustat hydrochloride | 210110-90-0 | 98.0% | 255.74 | 50 MG
Miglustat (N-Butyldeoxynojirimycin) hydrochloride is an orally active and reversible ceramide glucosyltransferase inhibitor, with blood-brain barrier permeability. It can be used for the research of type I gaucher disease.
- Orally active and reversible ceramide glucosyltransferase inhibitor
- Blood-brain barrier permeability
- Used for research of type I Gaucher disease
- Restores F508del-CFTR function in cystic fibrosis (CF) bronchial epithelial IB3-1 and CuFi-1 cells
- Reduces inflammatory response to P. aeruginosa in both CF and non-CF bronchial cells
- Able to rescue synaptic plasticity deficits, to restore ERKs activation and to counteract hyperexcitability in NPC1-/- mice
Medchemexpress LLC Azithromycin | 83905-01-5 | 98.0% | 748.98 | 1 ML
Azithromycin hydrate is a macrolide antibiotic useful for the treatment of a number of bacterial infections. It is intended for research use only.
- Enhances rhinovirus-induced IFNβ expression in primary bronchial epithelial cells from asthmatics.
- Represses viral replication.
- Reduces MMP-9 mRNA and protein levels without affecting NF-κB in endotoxin-challenged monocytic THP-1 cells.
- Augments expression of interferon-stimulated genes and the pattern recognition receptor MDA5.
Medchemexpress LLC Azithromycin | 83905-01-5 | 98.0% | 748.98 | 500 MG
Azithromycin is a macrolide antibiotic effective in treating various bacterial infections. It is intended for research use only.
- Macrolide antibiotic
- Useful for treating a number of bacterial infections
Medchemexpress LLC Ibuprofen-d3 | 121662-14-4 | 99.94% | C13H15D3O2 | 5 MG
Ibuprofen-d3 is a deuterium labeled Ibuprofen and functions as a COX-1 and COX-2 inhibitor. It is utilized as a tracer and internal standard for quantitative analysis in various analytical methods.
- Functions as a COX-1 and COX-2 inhibitor
- Can be used as a tracer
- Serves as an internal standard for quantitative analysis
- Suitable for methods like NMR, GC-MS, or LC-MS
- Deuterium labeling can affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Poly-L-ornithine hydrobromide | 27378-49-0 | 30000-70000 | 10 MG
Poly-L-ornithine hydrobromide (MW 30000-70000) is a poly-lysine derivative used as a coating agent in cell culture. It binds to cell culture vessel surfaces through positively charged amino acid residues, forming a coating that promotes cell adhesion and provides a matrix environment essential for cell growth. It is suitable for studying primary culture of neurons, including dopaminergic neurons and oligodendrocytes.
- Promotes cell adhesion
- Provides a matrix environment for cell growth
- Suitable for primary culture of neurons
- Can be used as an initial layer matrix for cell culture plates
- Provides a stable and reliable adhesion surface for differentiation studies of neural stem cells
Cayman Chemical Actinomycin D, Purity: ≥95%, CAS: 50-76-0, 25 mg
A cyclic polypeptide-containing anticancer antibiotic that binds to DNA and blocks transcription by interfering with RNA synthesis; ~10 nM promotes cell death in a variety of tumors
Cayman Chemical S-(5'-Adenosyl)-L-methionine (sulfate tosylate), Purity: ≥95%, CAS: 97540-22-2, 50 mg
A methyl donor and cofactor; involved in several biological processes, including epigenetic regulation, post-translational modification of proteins, and metabolism
Medchemexpress LLC L-2-hydroxyglutaric acid | 13095-48-2 | 95.1% | 148.11 | 10 MG
L-2-Hydroxyglutaric acid is an epigenetic modifier and putative oncometabolite in renal cancer. It can inhibit histone demethylases, thereby promoting histone methylation. L-2-Hydroxyglutaric acid also inhibits mitochondrial creatine kinase (Mi-CK) activity with Km and Ki values of 2.52 mM and 11.13 mM, respectively. It is potent at inhibiting 2-oxoglutarate (2-OG) dependent dioxygenases (2OGDs) including the Ten Eleven Translocation (TET) enzymes.
- Epigenetic modifier
- Putative oncometabolite in renal cancer
- Inhibits histone demethylases
- Inhibits mitochondrial creatine kinase (Mi-CK) activity
- Potent at inhibiting 2-oxoglutarate (2-OG) dependent dioxygenases (2OGDs)
- Human endogenous metabolite
Medchemexpress LLC Poly-L-ornithine hydrobromide | 27378-49-0 | 30000-70000 | 25 MG
Poly-L-ornithine hydrobromide is a poly-lysine derivative with a molecular weight ranging from 30000 to 70000. It binds to the surface of cell culture vessels through positively charged amino acid residues, forming a coating that promotes cell adhesion and provides cells with a matrix environment required for growth. It is used as a coating agent in cell culture and for the study of primary culture of neurons. It is identified for use as a laboratory chemical.
- Used as a coating agent in cell culture
- Promotes cell adhesion
- Provides cells with a matrix environment required for growth
- Supports the study of primary culture of neurons, including dopaminergic neurons and oligodendrocytes
- Can serve as a first layer matrix for cell culture plates
- Provides a stable adhesion surface for differentiation study of neural stem cells
Cambridge Isotope Laboratories ALGAL AMINO ACID MIXTURE (U-15N, 98%), 1 G
ALGAL AMINO ACID MIXTURE (U-15N, 98%), 1 G
Apexbio Technology LLC Dacarbazine 4342-03-4 200mg
Dacarbazine (CAS 4342-03-4) is a triazene-based alkylating agent widely used in biomedical research and oncology Upon metabolic activation dacarbazine generates reactive methylating species that transfer methyl groups primarily to the O6 and N7 positions of guanine bases within DNA This alkylation promotes DNA strand cross-linking and mispairing ultimately inducing apoptosis in rapidly dividing cells Dacarbazine is commonly applied in studies modeling malignant melanoma Hodgkin lymphoma sarcoma and pancreatic islet cell carcinoma Its mechanism of DNA damage and cytotoxicity also informs research into chemoresistance and combination chemotherapy regimens