Laboratory Specialty Services
Hampton Research MEMBFAC NO15 185ML
HR2-920-15/MembFac #15 (B3), 185 ml - 0.1 M Sodium chloride, 0.1 M Sodium citrate tribasic dihydrate pH 5.6, 12% v/v (+/-)-2-Methyl-2,4-pentanediol. Please note items from this supplier are non-returnable.
Apexbio Technology LLC SGI-1027 1020149-73-8 10mM (in 1mL DMSO)
SGI-1027 (CAS 1020149-73-8) is a small-molecule inhibitor of DNA methyltransferases (DNMTs) exhibiting IC50 values of 12 5 M for DNMT1 8 M for DNMT3A and 7 5 M for DNMT3B It acts by competitively inhibiting the cofactor Ado-Met binding site rather than the DNA substrate site resulting in reduced DNMT activity and subsequent inhibition of DNA methylation SGI-1027 suppresses both mammalian and bacterial DNMTs affecting endogenous and recombinant forms In cancer cell models it induces demethylation of CpG islands in gene promoter regions leading to reactivation of silenced tumor suppressor genes such as P16 and TIMP3 and promotes DNMT1 degradation via the proteasome pathway SGI-1027 is utilized in epigenetics research to study DNA methylation dynamics and gene reactivation
![Medchemexpress LLC 4-[[4-(4-chlorophenoxy)phenyl]sulfonylmethyl]-N-hydroxyoxane-4-carboxamide | 193022-04-7 | MFCD16657131 | 99.2% | 425.88 | C19H20ClNO6S | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000243576.png-250.jpg)
Medchemexpress LLC 4-[[4-(4-chlorophenoxy)phenyl]sulfonylmethyl]-N-hydroxyoxane-4-carboxamide | 193022-04-7 | MFCD16657131 | 99.2% | 425.88 | C19H20ClNO6S | 25 MG
CTS-1027 is a potent small-molecule inhibitor of matrix metalloproteinases (MMPs) with sub-nanomolar activity against MMP2 and MMP13 and strong selectivity over MMP1. It has been characterized in preclinical models for effects on hepatocyte apoptosis and fibrogenesis and is supplied for research use. The compound is a crystalline solid with high DMSO solubility and defined storage recommendations for powder and solutions.
- Potent inhibition of MMP2 and MMP13 at sub-nanomolar concentrations.
- Broad MMP activity including MMP12, MMP8, MMP3, and MMP14.
- Greater than 1,000-fold selectivity over MMP1.
- High solubility in DMSO enables concentrated stock preparation.
- Stable as powder under recommended cold storage conditions.
- Demonstrated activity in preclinical models of liver injury.
Hampton Research MEMBFAC NO38 185ML
HR2-920-38/MembFac #38 (D2), 185 ml - 0.6 M Magnesium sulfate hydrate, 0.1 M HEPES sodium pH 7.5, 4% v/v (+/-)-2-Methyl-2,4-pentanediol. Please note items from this supplier are non-returnable.
Sigma Aldrich Fine Chemicals Biosciences Acetyl coenzyme A sodium salt >=93% (HPLC), powder | 102029-73-2 | MFCD00078858 | 25MG
Acetyl coenzyme A sodium salt >=93% (HPLC), powder | Purity: >=93% (HPLC) | Mol Wt: 809.57 | 102029-73-2 | MFCD00078858 | 25MG
Hampton Research HR2-928-D2/Grid Screen PEG/LiCl #D2, 185 ml - 0.1 M Citric acid pH 5.0, 1.0 M Lithium chloride, 30% w/v Polyethylene glycol 6,000
HR2-928-D2/Grid Screen PEG/LiCl #D2, 185 ml - 0.1 M Citric acid pH 5.0, 1.0 M Lithium chloride, 30% w/v Polyethylene glycol 6,000. Please note items from this supplier are non-returnable.
Hampton Research HR2-944-90/Index #90 (H06), 185 ml - 0.2 M Sodium formate, 20% w/v Polyethylene glycol 3,350
HR2-944-90/Index #90 (H06), 185 ml - 0.2 M Sodium formate, 20% w/v Polyethylene glycol 3,350. Please note items from this supplier are non-returnable.
Apexbio Technology LLC DiscoveryProbe™ Apoptosis Compound Library 100uL/well(10 mM solution),96 Well Deep Well Plate
DiscoveryProbe Apoptosis Compound Library consists of 643 apoptosis-associated small molecules widely documented in scientific literature and approved by authoritative institutions including FDA The library targets key proteins involved in apoptosis signaling pathways such as caspases MDM2 TNF- and p53 facilitating comprehensive studies into programmed cell death mechanisms and related pathological conditions Representative compounds in this collection include selective caspase modulators TNF- pathway inhibitors and MDM2-p53 interaction agents Researchers can leverage this specialized library for apoptosis-focused drug screening mechanistic pathway exploration and therapeutic candidate identification in disease models characterized by apoptosis dysregulation
Hampton Research HR2-928-D4/Grid Screen PEG/LiCl #D4, 185 ml - 0.1 M HEPES pH 7.0, 1.0 M Lithium chloride, 30% w/v Polyethylene glycol 6,000
HR2-928-D4/Grid Screen PEG/LiCl #D4, 185 ml - 0.1 M HEPES pH 7.0, 1.0 M Lithium chloride, 30% w/v Polyethylene glycol 6,000. Please note items from this supplier are non-returnable.
Hampton Research HR2-944-93/Index #93 (H09), 185 ml - 0.05 M Zinc acetate dihydrate, 20% w/v Polyethylene glycol 3,350
HR2-944-93/Index #93 (H09), 185 ml - 0.05 M Zinc acetate dihydrate, 20% w/v Polyethylene glycol 3,350. Please note items from this supplier are non-returnable.
Hampton Research NATRIX NO27 185ML
HR2-918-27/Natrix #27 (C3), 185 ml - 0.2 M Ammonium acetate, 0.01 M Magnesium acetate tetrahydrate, 0.05 M Sodium cacodylate trihydrate pH 6.5, 30 % w/v Polyethylene glycol 8,000. Please note items from this supplier are non-returnable.
Inorganic Ventures pH 7 CALIBRATION STD 500mL
Inorganic Ventures' pH 7 Standard is a 500mL certified reference material set in a water matrix for stability. This standard is Traceable to NIST and manufactured in accordance with our stringent Quality Assurance guidelines. See Certificate of Analysis for expiration.
ATTENTION: Inorganic Ventures is no longer supplying paper copies of Certificate of Analyses(CoA) and Safety Data Sheets (SDS). Please use this link to download your copies: https://www.inorganicventures.com/coa-sds-search
Hampton Research HR2-944-63/Index #63 (F03), 185 ml - 5% v/v Tacsimate pH 7.0, 0.1 M HEPES pH 7.0, 10% w/v Polyethylene glycol monomethyl ether 5,000
HR2-944-63/Index #63 (F03), 185 ml - 5% v/v Tacsimate pH 7.0, 0.1 M HEPES pH 7.0, 10% w/v Polyethylene glycol monomethyl ether 5,000. Please note items from this supplier are non-returnable.
Hampton Research HR2-944-89/Index #89 (H05), 185 ml - 0.1 M Succinic acid pH 7.0, 15% w/v Polyethylene glycol 3,350
HR2-944-89/Index #89 (H05), 185 ml - 0.1 M Succinic acid pH 7.0, 15% w/v Polyethylene glycol 3,350. Please note items from this supplier are non-returnable.