Cayman Chemical DPP-9 InhIbItr 42 1mg
A FASN inhibitor (IC50 213 nM) inhibits the proliferation of PC3 and MV4-11 cells (IC50s 47 and 26 nM respectively) inhibits FASN activity in a 14C-acetate incorporation assay using BT474 cells (IC50 90 nM) reduces tumor growth and increases intratumoral levels of the FASN substrate malonyl-CoA in an MV4-11 mouse xenograft model at 25 and 50 mg/kg inhibits infection of HEK293T-hACE2 cells with SARS-CoV-2-mNG (EC50 17 nM)