Alogliptin-d3 is the deuterium labeled Alogliptin, a potent, selective, and orally active inhibitor of DPP-4 with an IC50 of <10 nM. It exhibits greater than 10,000-fold selectivity over DPP-8 and DPP-9 and can be used for the research of type 2 diabetes. Stable heavy isotopes, like deuterium, are incorporated into drug molecules for quantitation during drug development and can influence pharmacokinetic and metabolic profiles.
- Deuterium labeled Alogliptin.
- Potent, selective, and orally active inhibitor of DPP-4.
- Exhibits greater than 10,000-fold selectivity over DPP-8 and DPP-9.
- Suitable for research of type 2 diabetes.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.