Biochemical Reagents
Medchemexpress LLC Rebaudioside M (Standard) | 1220616-44-3 | 25 MG
Rebaudioside M (Standard) is the analytical standard of Rebaudioside M, intended for research and analytical applications. It is a non-calorie sweetener isolated from *Stevia rebaudiana*, a glycoside of the ent-kaurene diterpenoid aglycone, and is over 350 times sweeter than sucrose.
- Purity of 99.43%
- Used as an analytical standard for qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS
- Appearance is solid
- Color is white to off-white
- Isolated from plants (Leguminosae, Trifolium hybridum L., Compositae, and other families)
Medchemexpress LLC DL-Alanine-13C-3 | 131157-42-1 | 25 MG
DL-Alanine-13C-3 is a 13C-labeled DL-Alanine, an amino acid, and the racemic compound of L- and D-alanine. This laboratory chemical is intended for research use only by experienced personnel in appropriately equipped and authorized facilities. It plays a key role in the glucose-alanine cycle between tissues and the liver.
- Used as a reducing and capping agent for the production of nanoparticles
- Suitable for research on transition metal chelation, including Cu(II), Zn(II), and Cd(II)
- Classed as a sweetener, alongside glycine and sodium saccharin
Medchemexpress LLC Bruceine D | 21499-66-1 | 25 MG
Bruceine D is a Notch inhibitor that exhibits anti-cancer activity and induces apoptosis in various human cancer cells. It also serves as an effective botanical insect antifeedant with systemic properties, leading to potent pest growth inhibition. Additionally, Bruceine D demonstrates strong anthelmintic activity against *D. intermedius* with an EC50 value of 0.57 mg/L.
- Notch inhibitor
- Induces apoptosis in several human cancer cells
- Effective botanical insect antifeedant with systemic properties
- Causes potent pest growth inhibitory activity
- Strong anthelmintic activity against *D. intermedius*
- Purity: 99.50%
- Appearance: Solid, white to off-white
Medchemexpress LLC Nonanoic acid | 112-05-0 | 25 G
Nonanoic acid is a naturally-occurring saturated fatty acid with nine carbon atoms. It has been observed to significantly reduce bacterial translocation and enhance antibacterial activity. It also remarkably increases the secretion of porcine β-defensins 1 (pBD-1) and pBD-2 by upregulating endogenous host defense peptides to enhance intestinal epithelial immunological barrier function through histone deacetylase inhibition.
- Reduces bacterial translocation
- Enhances antibacterial activity
- Increases secretion of porcine β-defensins 1 and 2
- Upregulates endogenous host defense peptides
- Enhances intestinal epithelial immunological barrier function
- Acts via histone deacetylase inhibition
Medchemexpress LLC Arabinose | 147-81-9 | 250 MG
Arabinose is a five-carbon sugar commonly found in plants. It alleviates immune disorders and inflammation by promoting balanced immune responses and reducing inflammation. Arabinose serves as an intermediate in compound synthesis and can be used in studies related to immune disorders and inflammation.
- Five-carbon sugar commonly found in plants.
- Alleviates immune disorders and inflammation by promoting balanced immune responses and reducing inflammation.
- Intermediate in compound synthesis, useful in various chemical processes.
- Research applications, can be used in studies related to immune disorders and inflammation.
- Induces cytotoxicity, autophagy, and cell cycle arrest in breast cancer cells via the p38-MAPK signaling pathway (In Vitro).
- Induces CRTC1 expression and activates the ACSS2-PPARγ/TFEB-AMPK axis, exerting neuromodulatory/antidepressant effects in SH-SY5Y human neuroblastoma cells (In Vitro).
Medchemexpress LLC Ethyl β-D-glucopyranoside | 3198-49-0 | 25 MG
Ethyl β-D-glucopyranoside is an ethyl derivative that can be isolated from the ethanolic extract of Scabiosa stellata LS.
- Store at 4°C, protect from light.
- In solvent, store at -80°C for 6 months or -20°C for 1 month, protect from light.
- Soluble in DMSO at 100 mg/mL.
- Suitable for in vivo experiments with various solvent systems, achieving solubility of ≥ 2.5 mg/mL.
Medchemexpress LLC D-Glucuronic acid (Standard) | 6556-12-3 | 25 G
D-Glucuronic acid (Standard) is the analytical standard of D-Glucuronic acid, intended for research and analytical applications. It is a major component of many anti-inflammatory proteoglycans, which can promote embryonic development and inhibit cell aggregation. After being metabolized into ethyl glucuronide, D-Glucuronic acid activates Toll-like receptor 4 (TLR4), causing pain. D-Glucuronic acid and its derivative glucurono-lactone can serve as liver detoxifiers for human health prevention, and its derivatives also possess anti-tumor activity.
- Analytical standard for D-Glucuronic acid
- Intended for research and analytical applications
- Promotes embryonic development and inhibits cell aggregation
- Activates Toll-like receptor 4 (TLR4) when metabolized
- Serves as a liver detoxifier; derivatives possess anti-tumor activity
- Commonly used in HPLC, GC, and MS for research experiments
Medchemexpress LLC D-Glucose 6-phosphate sodium | 54010-71-8 | 98.0% | 282.12 | 500 MG
D-Glucose 6-phosphate sodium is an endogenous metabolite. It is for research use only and serves as a human endogenous metabolite.
- Solid appearance.
- White to off-white color.
- Shipping at room temperature in continental US; may vary elsewhere.
- Storage at 4°C, stored under nitrogen.
- In solvent: -80°C for 6 months; -20°C for 1 month (stored under nitrogen).
- Soluble in H2O: 50 mg/mL (177.23 mM; requires ultrasonic).
Medchemexpress LLC ME-344 | 1374524-68-1 | 99.80% | 348.39 | 100 MG
ME-344 is an Isoflavone that increases mitochondrial ROS generation, inhibits tubulin polymerization, inhibits HO-1 and impacts its mitochondrial translocation. It induces apoptosis through Caspase 3 activation and synergizes with Vinblastine in leukemia cells. It displays anti-tumor activity against leukemia and lung tumors and can be used in the research of lung cancer, acute myeloid leukemia, and HER2-negative breast cancer.
- Increases mitochondrial ROS generation.
- Inhibits tubulin polymerization.
- Inhibits HO-1 and impacts its mitochondrial translocation.
- Induces apoptosis through Caspase 3 activation.
- Synergizes with Vinblastine in leukemia cells.
- Displays anti-tumor activity against leukemia and lung tumor.
- Used in the research of lung cancer, acute myeloid leukemia, and HER2-negative breast cancer.
Medchemexpress LLC 1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine (DSPE) | 1069-79-0 | 100.0% | 748.07 | 500 MG
1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine (DSPE) is a phosphoethanolamine (PE) lipid used in the synthesis of liposomes. It cannot sustain a lamellar form at pH values below approximately 8.5, which is the pKa of the ethanolamine moiety. This product is for research use only.
- Phosphoethanolamine (PE) lipid
- Used in the synthesis of liposomes
- Cannot sustain lamellar form at pH values below approximately 8.5
- For research use only
Medchemexpress LLC Resolvin D2 | 810668-37-2 | 99.9% | 376.49 | 25 UG
Resolvin D2 is a metabolite derived from docosahexaenoic acid (DHA) that exhibits anti-inflammatory and anti-infective properties. It acts as a potent regulator of leukocytes and is effective in controlling microbial sepsis. This compound also functions as a remarkably potent inhibitor of TRPV1 (IC50 = 0.1 nM) and TRPA1 (IC50 = 2 nM) in primary sensory neurons.
- Anti-inflammatory activities
- Anti-infective activities
- Leukocyte regulation
- Control of microbial sepsis
- TRPV1 and TRPA1 inhibition
- Resolution of inflammation and tissue regeneration
- Decreases leukocyte:endothelial interactions
- Inhibits inflammatory pain
Apexbio Technology LLC Iniparib (BSI-201) 160003-66-7 50mg
Iniparib (BSI-201) (CAS 160003-66-7) is a small-molecule inhibitor initially characterized as targeting poly(ADP-ribose) polymerase-1 (PARP1) It is designed to inhibit PARP1 by promoting oxidation of zinc finger motifs leading to zinc ejection and suppression of enzyme activity Iniparib exerts its biological activity primarily through metabolism into a C-nitroso intermediate which modifies cysteine residues in multiple proteins In cellular assays Iniparib demonstrates growth-inhibitory activity with reported IC50 values approximately ranging from 40 to 100 M in cancer cell lines Based on these pharmacological properties Iniparib holds research potential in oncology studies particularly in treatment-resistant and solid tumor models
![Apexbio Technology LLC hemagglutinin precursor (114-122) amide [Influenza A virus] 25mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000095536.png-250.jpg)
Apexbio Technology LLC hemagglutinin precursor (114-122) amide [Influenza A virus] 25mg
Hemagglutinin precursor 114-122 amide is a synthetic peptide fragment derived from the hemagglutinin glycoprotein of Influenza A virus It is designed to present antigenic determinants that facilitate the analysis of peptide-MHC interactions and characterization of influenza-specific immune responses Hemagglutinin precursor 114-122 amide exerts its biological activity primarily by eliciting immune responses against Influenza A virus supporting studies on cytotoxic T-cell reactivity and antigenicity Based on these properties hemagglutinin precursor 114-122 amide holds research potential in immunological assays vaccine antigenicity studies and investigations of antiviral immune responses