Biochemical Reagents
Medchemexpress LLC Bet-bay 002 | 1588521-78-1 | 99.8% | 403.86 g/mol | C22H18ClN5O | 100MG
BET-BAY 002 is a small-molecule BET bromodomain inhibitor intended for research use. It demonstrates activity in multiple myeloma models and is provided as a high-purity solid for in vitro and preclinical studies. The compound is soluble in DMSO and is offered in multiple pack sizes to support assay development and screening.
- Potent BET bromodomain inhibitor with reported efficacy in multiple myeloma models.
- High purity (99.8%) suitable for biological assays.
- Soluble in DMSO for convenient reconstitution.
- Available in multiple quantities including a 100 mg package.
- Molecular weight 403.86 g/mol and formula C22H18ClN5O.
Medchemexpress LLC UDP-glucuronic acid trisodium | 63700-19-6 | 1 G
UDP-glucuronic acid trisodium (Uridine-5'-diphosphoglucuronic acid trisodium salt) is a crucial precursor for essential glycoconjugates found across various biological kingdoms, including mammalian glycosaminoglycans, plant cell wall polysaccharides, and bacterial capsule glycoglycerolipids. It is intended for research use only.
- Critical precursor for essential glycoconjugates
- Promotes migration of liver cancer cells in vitro
- Decreased E-cadherin and increased vimentin levels in liver cancer cells
- Molecular weight of 646.23
- Purity of 99.87%
- Appears as a white to off-white solid
Medchemexpress LLC 4-Methylumbelliferyl β-D-cellobioside | 72626-61-0 | MFCD00063279 | 99.4% | 500.45 | 100 MG
4-Methylumbelliferyl β-D-cellobioside is a substrate for cellulase. It can be hydrolyzed to produce fluorescent 4-methylumbelliferone, which is used to study the kinetics of cellulases.
- Substrate for cellulase
- Produces fluorescent 4-methylumbelliferone
- Used to study the kinetics of cellulases
Medchemexpress LLC Azido-PEG4-beta-D-glucose | 1609083-15-9 | 99.9% | 381.38 | 25 MG
Azido-PEG4-beta-D-glucose is a PEG-based PROTAC linker that facilitates the synthesis of PROTACs. This click chemistry reagent contains an Azide group, allowing it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups.
- PEG-based PROTAC linker
- Utilized in PROTAC synthesis
- Functions as a click chemistry reagent
- Contains an azide functional group
- Participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Enables strain-promoted alkyne-azide cycloaddition (SPAAC)
- Intended for research use only
Medchemexpress LLC D-Dimannuronic acid sodium | 10 MG
D-Dimannuronic acid sodium is an alginate extract derived from brown algae. This compound is primarily used in research to synthesize sulfated polymannuronate (SPMG)-derived oligosaccharides. It is intended for research use only.
- Derived from brown algae
- Used to synthesize sulfated polymannuronate (SPMG)-derived oligosaccharides
- For research use only
- Purity of 99.94%
- Molecular weight of 392.25
- Molecular formula is C12H17NaO13
- Appears as a white to off-white solid
- Soluble in H2O at 125 mg/mL (318.67 mM), requires ultrasonic treatment
Medchemexpress LLC Thymine 1-β-D-arabinofuranoside | 605-23-2 | 98.0% | 258.23 | 25 MG
Thymine 1-β-D-arabinofuranoside is a purine nucleoside analogue. Purine nucleoside analogs exhibit broad antitumor activity, specifically targeting indolent lymphoid malignancies. The anticancer mechanisms include inhibition of DNA synthesis and induction of apoptosis.
- Purine nucleoside analogue
- Exhibits broad antitumor activity
- Targets indolent lymphoid malignancies
- Inhibits DNA synthesis
- Induces apoptosis
- Solid appearance
- Off-white to light yellow color
- Melting/freezing point: 246-247°C
- Recommended storage: 4°C, stored under nitrogen
Cayman Chemical D-GlucuronIc AcId 5g
A metabolite of glucose; a component of proteoglycans; levels are increased in fibroblasts isolated from patients with ISSD or Salla disease
Medchemexpress LLC IL-1RA/IL-1F3 Porci 5ug | 5ug
IL-1RA/IL-1F3 proteins are powerful anti-inflammatory antagonists in the interleukin 1 family specifically targeting the pro-inflammatory cytokines IL1B and IL1A This protein counteracts the inflammatory effects of IL1 playing a critical role in preventing immune dysregulation and preventing uncontrolled systemic inflammation triggered by a variety of innate irritants including pathogens IL-1RA/IL-1F3 Protein Porcine is the recombinant Porcine-derived IL-1RA/IL-1F3 protein expressed by E coli with tag free
Medchemexpress LLC Glucuronic acid sodium | 7182-77-6 | 1 MG
Glucuronic acid sodium is a polysaccharide that exhibits anti-inflammatory activity, supporting the healing of ulcerative colitis. It also enhances the intestinal barrier by upregulating tight junction proteins like ZO-1 and Occludin. Additionally, it modulates gut microbiota by increasing beneficial bacterial populations while suppressing harmful ones.
- Exhibits anti-inflammatory activity
- Supports healing of ulcerative colitis
- Enhances intestinal barrier function
- Modulates gut microbiota
- Increases beneficial bacterial populations
- Suppresses harmful bacterial populations
Medchemexpress LLC D-3263 hydrochloride | 1008763-54-9 | MFCD22665741 | 98.0% | 409.95 | C21H32ClN3O3 | 10 MG
D-3263 hydrochloride is an enteric-coated, orally bioavailable agonist of transient receptor potential melastatin member 8 (TRPM8). It binds and activates TRPM8, modulates calcium and sodium flux, and has been investigated for potential antineoplastic effects and modulation of androgen-related pathways.
- Orally bioavailable TRPM8 agonist suitable for in vivo studies.
- Enteric-coated formulation for improved gastrointestinal stability.
- High purity (98.0%) supports reproducible experimental results.
- Soluble in DMSO and formulatable for common in vivo vehicles.
- Stable when stored sealed at 4°C; solvent stability at -80°C for extended storage.
Medchemexpress LLC Sodium zirconium cyclosilicate | 17141-74-1 | 95.0% | 50 MG
Sodium zirconium cyclosilicate is an inorganic, microporous zirconium silicate cation exchanger used in research to selectively remove excess potassium (K+) in vivo. It is supplied for preclinical and biochemical studies, including hyperkalemia and chronic kidney disease research, and is provided at laboratory-grade purity.
- Selective potassium binding for ion-exchange studies.
- Non-absorbed inorganic sorbent suitable for in vivo models.
- Supplied at 95.0% purity for consistent results.
- Available in small research pack sizes from 5 mg to 500 mg.
- Useful for biochemical assays and renal disease research.
Cayman Chemical 13C6-4-NItronIlIn 10mg
An internal standard for the quantification of 4-nitroaniline by GC- or LC-MS
Medchemexpress LLC UDP-3-O-acyl-GlcNAc | 108636-29-9 | 1 MG
UDP-3-O-acyl-GlcNAc is an E. coli metabolite involved in the 3-deoxy-D-manno-octulosonate (KDO) biosynthesis pathway. It has a molecular weight of 833.71 and a chemical formula of C31H53N3O19P2. This product is for research use only.
- Molecular weight: 833.71
- Formula: C31H53N3O19P2
- Initial source: Microorganisms (Escherichia)
- For research use only
Medchemexpress LLC 4-Methylumbelliferyl-α-D-Glucopyranoside | 17833-43-1 | 99.99% | 338.31 | 1 ML
4-Methylumbelliferyl-α-D-Glucopyranoside is a fluorescent substrate for α-glucosidase. Upon cleavage, it releases the fluorescent moiety 4-methylumbelliferyl (4-MU), which exhibits pH-dependent fluorescence excitation activity. Excitation wavelengths are 320 nm at low pH (1.97-6.72) and 360 nm at high pH (7.12-10.3), with emission wavelengths ranging from 445-455 nm as pH decreases.
- Used as a biomarker to quantify α-glucosidase activity in infant blood spot samples for Fabry and Pompe diseases.
- Intended for research use only.
- Not sold to patients.
Medchemexpress LLC Bet-in-19 | 1643947-30-1 | 99.7% | 333.39 | C19H19N5O | 10MG
BET-IN-19 is a small-molecule BET bromodomain inhibitor provided as a high-purity research reagent for epigenetic and oncology studies. It is supplied as a powder in multiple pack sizes and displays cellular activity against AML MV4-11 cells, supporting biochemical and cell-based assays. Recommended storage: powder -20°C; in solvent -80°C (6 months) or -20°C (1 month).
- High purity (99.74%).
- Molecular formula C19H19N5O; molecular weight 333.39.
- Demonstrated inhibition of hIL-6 transcription and c-myc activity (IC50 ≤ 0.3 μM).
- Available in multiple pack sizes for flexible experimental design.
- Supplied as a powder with defined cold-storage stability.