The DOCK5 (E6R9W) Rabbit Monoclonal Antibody is a recombinant antibody that recognizes endogenous levels of total DOCK5 protein. This antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Pro1863 of human DOCK5 protein. DOCK5, a Rho family guanine nucleotide exchange factor (GEF), plays an essential role in generating the sealing zone, an osteoclast-specific adhesion structure involved in bone resorption. The antibody is supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 μg/mL BSA, 50% glycerol, and less than 0.02% sodium azide.
- Validated for western blotting (1:1,000 dilution) and immunoprecipitation (1:50 dilution)
- Species reactivity specific to human
- Molecular weight of 215 kDa
- Store at -20°C; do not aliquot the antibody