PI4KIIIbeta-IN-10 is a potent and selective inhibitor of PI4KIIIβ, demonstrating an IC50 of 3.6 nM. This compound exhibits minimal off-target inhibition of related lipid kinases, showing weak inhibition of PI3KC2γ, PI3Kα, and PI4KIIIα, and less than 20% inhibition for PI4K2α, PI4K2β, and PI3Kβ at concentrations up to 20 μM. It is designed for research use only, providing a valuable tool for scientific investigations.
- Potent PI4KIIIβ inhibitor with high selectivity
- Minimal off-target activity against related lipid kinases
- Available in various quantities and formulations
- Suitable for research applications