Carbohydrates
![Medchemexpress LLC [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-substance P | 96736-12-8 | MFCD00076802 | 98.5% | 1,516.83 g/mol | C79H109N19O12 | 1 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000248200.png-250.jpg)
Medchemexpress LLC [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-substance P | 96736-12-8 | MFCD00076802 | 98.5% | 1,516.83 g/mol | C79H109N19O12 | 1 MG
[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-substance P is a synthetic peptide analog of Substance P bearing D-amino acid substitutions that alter receptor signaling. It is used in research to probe neuropeptide and chemokine receptor pharmacology, intracellular signaling pathways, and cellular responses in inflammation and cancer studies.
- Acts as a biased agonist at neuropeptide and chemokine receptors.
- Activates G12 and modulates ERK-2 and JNK signaling pathways.
- Promotes neutrophil migration and intracellular Ca2+ mobilization.
- Functions as a bombesin antagonist and shows activity in small cell lung cancer models.
- Peptide sequence contains D-Arg, D-Phe, and D-Trp substitutions; molecular weight ≈ 1,516.83 g/mol.
- Provided as a high-purity powder; store sealed, away from moisture, at -20°C to -80°C for long-term stability.
eMolecules 56-81-5 | Glycerin USP grade | Oakwood Chemicals | MFCD00004722 | 92.094 | C3H8O3 | 99.000 | OCC(O)CO | 1kg | 480152362
Glycerin USP grade | Oakwood Chemicals | 56-81-5 | MFCD00004722 | 92.094 | C3H8O3 | 99.000 | OCC(O)CO | 1kg | 480152362
Medchemexpress LLC Alpha-lactose monohydrate | 5989-81-1 | MFCD00150747 | >99.0% | 360.31 g/mol | C12H24O12 | 1 ML
Alpha-lactose monohydrate is a disaccharide derived from glucose and galactose commonly used as an excipient, diluent, and analytical standard in pharmaceutical and biochemical research. It is available either as a bulk solid or as small-volume prepared solutions for laboratory use.
- Used as an excipient and diluent in pharmaceutical formulations.
- Serves as an analytical reference standard and reagent for biochemical assays.
- Available as solid bulk material and as small-volume solution formulations for convenience.
- Chemical formula C12H24O12 and molecular weight 360.31 g/mol.
- Supplied with product documentation such as datasheet, certificate of analysis, and safety data sheet.
eMolecules 2168552-79-0 | 1-METHYLCYCLOBUTANE-1,3-DIOL | AstaTech102.133 | C5H10O2 | 95.000 | CC1(O)CC(O)C1 | 0.1g | 801703731
1-METHYLCYCLOBUTANE-1,3-DIOL | AstaTech | 2168552-79-0102.133 | C5H10O2 | 95.000 | CC1(O)CC(O)C1 | 0.1g | 801703731
Medchemexpress LLC Plantainoside D | 147331-98-4 | 5 MG
Plantainoside D is a phenylethanoid glycoside and an IKK-β inhibitor with diverse biological activities. It shows inhibitory activity of angiotensin-converting enzyme (ACE) and reduces glutamate release from nerve terminals. It also alleviates cell apoptosis and improves acute lung injury (ALI) induced by sepsis, making it suitable for studies in neuroprotection, antioxidant, anti-inflammation, and antihypertension.
- Phenylethanoid glycoside and an IKK-β inhibitor
- Inhibits angiotensin-converting enzyme (ACE) with an IC50 of 2.17 mM
- Reduces glutamate release from nerve terminals by inhibiting voltage-dependent calcium channels and protein kinase C signaling
- Alleviates cell apoptosis by inhibiting ROS generation and NF-κB activation
- Improves acute lung injury (ALI) induced by sepsis by regulating the Sirt3/NLRP3 signaling pathway
Medchemexpress LLC a-D-Galactose pentaa 10g
-D-Galactose pentaacetate (Pentaacetyl- -D-galactopyranose) is a biochemical reagent that can be used as a biological material or organic compound for life science related research
Medchemexpress LLC 3-O-Methyl-D-chiro-inositol | 10284-63-6 | 194.18 | 1 ML
D-pinitol is a natural compound found in various plants, including Pinaceae and Leguminosae. It is recognized for its hypoglycemic activity and its protective effects on the cardiovascular system. Additionally, D-pinitol exhibits antiviral and larvicidal properties.
- Natural compound found in plants.
- Exerts hypoglycemic activity.
- Provides protective effects in the cardiovascular system.
- Possesses antiviral activity.
- Exhibits larvicidal activity.
- Promotes apoptosis in cells.
![Medchemexpress LLC [D-Ala2]-GIP (human) | 444073-04-5 | 99.0% | 4983.60 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000397301.png-250.jpg)
Medchemexpress LLC [D-Ala2]-GIP (human) | 444073-04-5 | 99.0% | 4983.60 | 5 MG
[D-Ala2]-GIP (human) is a GIP receptor agonist (EC50 = 630 pM) that improves glucose tolerance and shows neuroprotective activity. It also enhances cognitive function and hippocampal synaptic plasticity, making it suitable for research in type 2 diabetes, Parkinson's disease, and related areas. This product is for research use only.
- Significantly reduces blood glucose fluctuations by stimulating insulin release.
- Attenuates the behavioral phenotype of Parkinson's disease.
- Reverses the decline in motor ability and muscle stiffness.
- Reduces increased tremor amplitude and inhibits the increase of MDA levels in the brain.
- Improves cognitive function and hippocampal synaptic plasticity.
Medchemexpress LLC (D)-PPA 1 TFA | 99.3% | 1669.67 | 5 MG
(D)-PPA 1 TFA is a hydrolysis-resistant d-peptide antagonist and a potent PD-1/PD-L1 inhibitor. It binds to PD-1 with an affinity of 0.51 μM and demonstrates both in vitro and in vivo efficacy, making it suitable for cancer immunotherapy research.
- Hydrolysis-resistant d-peptide antagonist.
- Potent PD-1/PD-L1 inhibitor.
- Binds to PD-1 with 0.51 μM affinity.
- Demonstrates in vitro and in vivo efficacy.
- Blocks the interaction between PD-1/PD-L1 at 1.0 mg/mL.
- Does not directly kill tumor cells or affect CT26 cell growth (3.125-100 μM over 24-48 hours in vitro).
- Inhibits CT26 tumor growth in mice (2 mg/kg; s.c. or i.p.; once daily for 7 d).
- Can target tumor tissue in CT26-tumor-bearing mice (40 μg/mouse in 200 μL; i.v.; single dose).
- High purity: 99.3%.
- Appearance: Solid, white to off-white.