Carbohydrates
Chem-Impex International, Inc. n-Octyl-b-D-glucopyranoside | 29836-26-8 | MFCD00063288 | 5G
n-Octyl-b-D-glucopyranoside, 29836-26-8, MFCD00063288, 5G
Sigma Aldrich Fine Chemicals Biosciences 3dGROTM Colon Intestinal O
Patient derived organoids (PDOs) are novel in vitro 3D cell models that preserve original tissue physiology and molecular pathology thus representing a clinically-relevant alternative to traditional 2D cell lines and an effective tool to refine and reduce animal models. PDOs can be derived from adult patient biopsies or resected tissues containing native LGR5 stem cell populations and cultured within an ECM-rich substrate using specialized organoid media such as L-WRN conditioned media. Adult tissue derived organoids are phenotypically and genetically stable in long term culture presenting more mature phenotypes compared to iPSC-derived organoids. Importantly PDOs have shown to be able to predict patient clinical responses to chemotherapeutics.We are now offering a comprehensive biobank of highly characterized tissue-derived human gastrointestinal organoids from normal and diseased patients. The intestinal organoid biobank contains over 50 highly characterized intestinal organoids f
Medchemexpress LLC K-Ras ligand-Linker Conjugate 4 | 2378261-83-5 | 98.8% | 25 MG
K-Ras ligand-Linker Conjugate 4 incorporates a ligand for the K-Ras recruiting moiety and a PROTAC linker. This linker recruits E3 ligases such as VHL, CRBN, MDM2, and IAP. It can be used in the synthesis of PROTAC K-Ras Degrader-1, a potent PROTAC K-Ras degrader that achieves ≥70% degradation efficacy in SW1573 cells. PROTACs consist of two different ligands connected by a linker: one for an E3 ubiquitin ligase and the other for the target protein, utilizing the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Incorporates a ligand for the K-Ras recruiting moiety
- Includes a PROTAC linker that recruits E3 ligases (VHL, CRBN, MDM2, and IAP)
- Utilizes the intracellular ubiquitin-proteasome system to selectively degrade target proteins
- Can be used in the synthesis of PROTAC K-Ras Degrader-1
- For research use only
Chem-Impex International, Inc. Salicin from Plant Extract | MFCD00006590 | 25G
Salicin from Plant Extract, MFCD00006590, 25G
Sigma Aldrich Fine Chemicals Biosciences 5-Bromo-4-chloro-3-indolyl alpha-D-glucopyranoside >=98.0% (HPLC) | 108789-36-2 | MFCD00155606 | 25MG
5-Bromo-4-chloro-3-indolyl alpha-D-glucopyranoside >=98.0% (HPLC) | Purity: >=98.0% (HPLC) | Mol Wt: 408.63 | 108789-36-2 | MFCD00155606 | 25MG
Cell Signaling Technology IGF-I Receptor beta (111A9) Rabbit mAb 20 ul
IGF-I Receptor beta (111A9) Rabbit mAb 20 ul
Sigma Aldrich Fine Chemicals Biosciences Glycerol puriss., meets analytical specification of Ph. Eur., BP, USP, FCC, E422, anhydrous, 99.0-101.0% (alkalimetric) | 56-81-5 | MFCD00004722 | 1l
Glycerol puriss., meets analytical specification of Ph. Eur., BP, USP, FCC, E422, anhydrous, 99.0-101.0% (alkalimetric) | Mol Wt: 92.09 | 56-81-5 | MFCD00004722 | 1l
Cell Signaling Technology Hemoglobin beta (D4W4I) Rabbit mAb 20 ul
Hemoglobin beta (D4W4I) Rabbit mAb 20 ul
Cell Signaling Technology beta-Arrestin 1 (D8O3J) Rabbit mAb 20 ul
beta-Arrestin 1 (D8O3J) Rabbit mAb 20 ul
Medchemexpress LLC Glucose-6-phosphate dehydrogenase, Bacillus sp. | 9001-40-5 | MFCD00081656 | 104 kDa | 10KU
Glucose-6-phosphate dehydrogenase from Bacillus sp. is a research-grade enzyme that catalyzes the oxidation of glucose-6-phosphate to 6-phosphogluconolactone with concurrent reduction of NADP+ to NADPH. Supplied as an activity-grade preparation (10 KU), it is intended for enzymatic assays, NADPH regeneration, and metabolic studies, including investigations of diabetes-related pathways.
- Source organism: Bacillus sp.
- Activity-grade pack: 10 KU
- Catalyzes oxidation of glucose-6-phosphate, producing NADPH
- Suitable for enzymatic assays and NADPH regeneration systems
- Useful for metabolic and diabetes-related research
- Provided as a research reagent; not for clinical use