Choose the brand aligned with your industry so we can best serve your needs.
For researchers, scientists, and technical professionals: Your one-stop shop for the complete range of laboratory, production, and safety products and services.
Various organic compounds consisting of carbon, hydrogen, and oxygen atoms that are found in foods and living tissues; typically broken down to release energy; includes sugars, sugar alcohols, sugar acids and derivatives, glycosyl compounds, and more.
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
USP7 Ligand-Linker Conjugates 1 is a Target Protein Ligand-Linker Conjugate designed for the synthesis of PROTAC USP7 Degrader-1. This product incorporates a ligand for USP7 and a PROTAC linker, which recruits E3 ligases. PROTACs operate by exploiting the intracellular ubiquitin-proteasome system to selectively degrade target proteins. It is intended for use as laboratory chemicals and in the manufacture of substances for research purposes only, to be handled by suitably qualified and experienced scientists in appropriately equipped and authorized facilities.
Incorporates a ligand for USP7
Recruits E3 ligases
Used for the synthesis of PROTAC USP7 Degrader-1
Exploits the intracellular ubiquitin-proteasome system
Selectively degrades target proteins
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Sigma-LIGAND-1 is a selective Sigma Receptor ligand with an IC50s of 16 nM 19 nM at the DTG site and the PPP site respectively. Sigma-LIGAND-1 has a Ki of 4000 nM at the dopamine D2 receptor. purity: 100%
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
GDP-D-mannose disodium is an endogenous metabolite consisting of GDP-α-D-mannose and GDP-β-D-mannose. GDP-α-D-mannose acts as the donor substrate for mannosyltransferases and serves as the precursor for GDP-β-L-fucose. It exhibits competitive inhibition with respect to GTP and uncompetitive inhibition with respect to mannose-1-P. This product is intended for research use only.
Comprises GDP-α-D-mannose and GDP-β-D-mannose
Donor substrate for mannosyltransferases
Precursor for GDP-β-L-fucose
Exhibits competitive inhibition with GTP (Ki 14.7 μM)
Exhibits uncompetitive inhibition with mannose-1-P (Ki 115 μM)
Molecular weight: 649.30
Chemical formula: C16H23N5Na2O16P2
Appearance: Solid, white to off-white
Classified as an endogenous metabolite
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
U-Blot Pan-O-GlcNAc Rabbit pAb is a Rabbit-derived polyclonal antibody that specifically recognizes O-GlcNAc a o-glcnacylation modification at Ser(S)/Thr(T) O-GlcNAc (short for O-linked -N-acetylglucosamine) is a reversible enzymatic post-translational modification found on serine and threonine residues of nucleocytoplasmic proteins The modification is characterized by a -glycosidic bond between the hydroxyl group of serine or threonine side chains and N-acetylglucosamine (GlcNAc) It is widely involved in the regulation of diverse cellular processes including transcription cell cycle signal transduction and stress response Dysregulation of O-GlcNAcylation has been closely linked to cancer neurodegeneration diabetes and inflammatory diseases Notably elevated O-GlcNAc levels in many cancers have been reported to suppress apoptosis by inhibiting caspase activation Supplied as 100 uL
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
D(+)-Galactosamine (hydrochloride) (Standard) is the analytical standard for D(+)-Galactosamine (hydrochloride), intended for research and analytical applications. It is an established experimental toxin that primarily causes liver injury through the generation of free radicals and depletion of UTP nucleotides. Intoxication with D(+)-Galactosamine hydrochloride also induces renal dysfunction, with renal failure often accompanying the end-stage of liver damage. The Lipopolysaccharide/D(+)-Galactosamine-induced acute liver injury model is a known animal model used for fulminant hepatic failure.
Analytical standard for D(+)-Galactosamine (hydrochloride).
Used in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS.
The compound is a grade of analytical standard, serving as a reference standard for assay.
Available in various quantities (e.g., 10 mg, 25 mg, 50 mg, 100 mg, 250 mg).
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More