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Various organic compounds consisting of carbon, hydrogen, and oxygen atoms that are found in foods and living tissues; typically broken down to release energy; includes sugars, sugar alcohols, sugar acids and derivatives, glycosyl compounds, and more.
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IL-36 beta (IL-1F8) a subform of IL-36 family belongs to IL-1 superfamily IL-36 beta mediates inflammatory response L-36 beta binds to IL-36R and recruits the co-receptor IL-1RacP and thereby activating NF- B and MAPK signaling pathways but the activation requires N-terminal cleavage by neutrophil granule-derived proteases[1][2] IL-36 beta/IL-1F8 Protein Human is a recombinant human IL-36 beta without any tag which is produced in E coli
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CMP-Sialic acid sodium salt is a nucleotide sugar involved in the biosynthesis of sialic acid. It functions as an allosteric inhibitor of UDP-GlcNAc 2-epimerase and provides a substrate for Golgi sialyltransferases, making it useful for enzymatic sialylation and studies of glycan modification in biochemical research.
Provides substrate activity for Golgi sialyltransferases.
Acts as an allosteric inhibitor of UDP-GlcNAc 2-epimerase.
Supports enzymatic sialylation and glycan modification studies.
Supplied as a solid, white to off-white, with defined storage stability.
Available in small research-scale quantities for laboratory use.
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GA-017 is a potent, selective small-molecule inhibitor of LATS1 and LATS2 kinases that activates YAP/TAZ signaling, promotes cell proliferation in 3D culture, and enhances intestinal organoid formation. It is supplied as a high-purity research reagent for studies of cell signaling and stem cell/Wnt pathways.
Potent LATS1/2 inhibition with low-nanomolar IC50 values.
Promotes YAP/TAZ activation and nuclear translocation.
Enhances cell proliferation in 3D culture and organoid formation.
High purity suitable for biochemical and cellular assays.
Soluble in DMSO at approximately 20.8 mg/mL; may require warming and sonication.
Stable as a powder when stored at low temperatures for long-term use.
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β-Cyclodextrin is a cyclic oligosaccharide composed of seven α-D-glucopyranose units commonly used in research to enhance the solubility and bioavailability of poorly soluble compounds; it has also been reported to exhibit anti-influenza activity. Supplied as a white to off-white solid for laboratory use.
Composed of seven glucose units (heptasaccharide).
Enhances solubility and bioavailability of hydrophobic agents.
High purity (99.95%).
Water solubility approximately 7 mg/mL; ultrasonic assistance may be required.
Molecular weight 1134.98 g/mol.
Powder storage recommended at -20°C (long term) or 4°C (short term).
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IL-20R beta Protein (IL20RB) is the beta subunit of IL-20 receptor forms functional heterodimers with different subunit protein and involves in STAT3 activation pathway[1] The IL-20RA/IL-20RB dimer is a receptor for IL-19 IL-20 and IL-24 The IL-22RA1/IL-20RB dimer is a receptor for IL-20 and IL-24[2] IL-20R beta Protein is consists of 308 amino acids (M1-T308) with a transmembrane domain (226-249 a a ) IL-20R beta Protein Rat (HEK293 Fc) is produced in HEK293 cells with a C-Terminal hFc-tag
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Beta-Galactosidase Reporter Assay Kit is a colorimetric assay system designed to quantify gene expression by measuring -galactosidase enzyme activity It facilitates the evaluation of transcriptional activity in biological samples Beta-Galactosidase Reporter Assay Kit exerts its function by enabling the -galactosidase-mediated hydrolysis of ortho-nitrophenyl- -D-galactopyranoside (ONPG) generating a yellow product detectable at 420 nm In cell-based studies this assay is commonly utilized alongside luciferase-based systems for dual-reporter experiments to normalize for transfection efficiency Based on these features Beta-Galactosidase Reporter Assay Kit is broadly applicable in gene expression analysis signal transduction research and studies requiring normalization controls
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