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Icatibant Acetate (CAS No 138614-30-9) is a synthetic peptide and a selective bradykinin B2 receptor antagonist used in biomedical research for its ability to inhibit bradykinin-induced responses Originating from efforts to manage hereditary angioedema it acts by blocking the B2 receptor pathway preventing vasodilation and vascular permeability Its in vitro activity is observed in the nanomolar range It is commonly applied in cell-based assays animal models and drug screening to explore inflammatory responses and vascular permeability Experimental concentrations typically depend on the specific research design
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A3551 is a small molecule compound designed to modulate specific cellular signaling pathways implicated in various pathological states It functions primarily by targeting kinase-mediated pathways thereby influencing intracellular signaling cascades associated with cell proliferation and differentiation Due to its pathway-specific mechanism of action A3551 is valuable for biomedical research examining signal transduction mechanisms oncogenesis processes and potential therapeutic intervention strategies
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Also available in 1 mg, 2 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Ergosterol Acetate (Ergosta-5,7,22-trien-3-beta-yl acetate) is one of the acetate derivatives of Ergosterol from Monascus anka. Purity 98.44%
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Also available in 1 mL, 1 mg, 5 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. 1. Alisol A 24-acetate (Alisol A monoacetate) has been determined for the quality control of this crude drug. Purity 99.07%
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NN1213 acetate is a long-acting human amylin peptide analog that functions as a selective Amylin receptor agonist. This compound significantly reduces food intake and fat mass, and has been shown to decrease body weight in diet-induced obese rats, making it suitable for research related to obesity.
Functions as a selective Amylin receptor agonist
Exhibits EC50 values of 0.177 nM for hAMY3R and 0.262 nM for rAMY3R
Reduces food intake and fat mass
Decreases body weight in diet-induced obese rats
Suitable for obesity research
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Also available in 1 mL, 2 mg, 5 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Ko 143 is a selective inhibitor of ATP-binding cassette sub-family G member 2 (ABCG2; BCRP). Purity 99.89%
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Also available in 1 mL, 10 mg, 25 mg and bulk. Please contact Fisher for quotes. SPI-112, the SPI-112 methyl ester analog, can inhibit cellular Shp2 PTP activity. SPI-112 bound to Shp2 by surface plasmon resonance (SPR) and displayed competitive inhibitor kinetics to Shp2. Purity 100%
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