Lipids and Lipid Derivatives
Medchemexpress LLC 3-epi-Vitamin D3 (Epicholecalciferol) | 57651-82-8 | C27H44O | 25 MG
3-epi-Vitamin D3 (Epicholecalciferol) is a Vitamin D3 analogue. It acts as a Hedgehog pathway inhibitor with an IC50 of 39.2 μM in U87MG cells and significantly upregulates Cyp24A1 in U87MG, HT-29, and C3H10T1/2 cells.
- Acts as a Hedgehog pathway inhibitor
- Upregulates Cyp24A1 in U87MG, HT-29, and C3H10T1/2 cells
- Appears as a white to light yellow solid
Medchemexpress LLC Verapamil-d3 hydrochloride | 2714485-49-9 | 99.57% | C27H36D3ClN2O4 | 5 MG
Verapamil-d3 hydrochloride is the deuterium labeled Verapamil hydrochloride. Verapamil hydrochloride is a calcium channel blocker and a potent, orally active first-generation P-glycoprotein (P-gp) inhibitor. It also inhibits CYP3A4 and has potential for research into high blood pressure, heart arrhythmias, and angina.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stable heavy isotopes have been incorporated into drug molecules for quantitation during drug development
- Deuteration has potential to affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC HY-32339 1mg Medchemexpress, Maxacalcitol CAS:103909-75-7 Purity:>98%
Medchemexpress, HY-32339 1mg Maxacalcitol CAS:103909-75-7 Maxacalcitol (22-Oxacalcitriol) is non-calcemic vitamin D3 analog and ligand of VDR-like receptors. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC 3-O-Methyldopa-d3 hydrate | 300-48-1 | 232.25 | 1 MG
3-O-Methyldopa-d3 (hydrate) is the deuterium labeled 3-O-Methyldopa. 3-O-Methyldopa (3-Methoxy-L-tyrosine) hydrate is a metabolite of L-DOPA that can cross the blood-brain barrier (BBB). 3-O-Methyldopa hydrate inhibits the astrocyte-mediated protective effect of L-DOPA on dopaminergic neurons. In addition, 3-O-Methyldopa hydrate has certain antidepressant and neuroprotective activities. 3-O-Methyldopa hydrate can be used in the research of nervous system diseases such as depression and Parkinson's disease.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC 1-Methyladenosine-d3 hydriodide | 15763-06-1 | 98.8% | 412.20 | 1 MG
1-Methyladenosine-d3 hydriodide is a deuterium-labeled version of 1-Methyladenosine. This RNA modification serves as a tumor marker, with elevated levels linked to cancer development. Its methylation leads to the upregulation of PPARδ expression, regulating cholesterol metabolism and activating the Hedgehog signaling pathway, contributing to liver tumorigenesis. This compound is intended for research use only and can be used as a tracer and internal standard for quantitative analysis.
- Deuterium-labeled version of 1-Methyladenosine
- Functions as a tumor marker
- Upregulates PPARδ expression
- Regulates cholesterol metabolism
- Activates Hedgehog signaling pathway
- Contributes to liver tumorigenesis
- Suitable as a tracer for quantitative analysis
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC 2-Nonenal-9,9,9-d3, 4-hydroxy-, (E)- | 148706-06-3 | 99.0% | 159.24 | 50 UG
4-Hydroxynonenal-d3 is the deuterium labeled form of 4-Hydroxynonenal (4-HNE), an α,β unsaturated hydroxyalkenal and an oxidative/nitrosative stress biomarker. It acts as both a substrate and an inhibitor of acetaldehyde dehydrogenase 2 (ALDH2). This compound modulates signaling processes by forming covalent adducts with nucleophilic functional groups in proteins, nucleic acids, and membrane lipids, and plays an important role in cancer through mitochondria.
- Functions as a tracer and internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stored as a solution at -20°C, protected from light, for up to 2 years.
- For research use only.
- Deuterium labeling can influence pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC 2-imidazolidinone, 1-phenyl-3-(2-piperidinylmethyl)-, hydrochloride | 1257326-24-1 | 98.3% | 295.81 g/mol | C15H22ClN3O | 100 MG
Dopamine D2 receptor agonist-3 is a small-molecule research compound described as a selective dopamine D2 receptor partial agonist and a dopamine D3 receptor antagonist. Supplied as the hydrochloride salt in solid form, it is intended for in vitro and preclinical receptor pharmacology studies; not for human use.
- Selective D2 partial agonist (pEC50 = 8.3)
- D3 antagonist activity (pEC50 < 5.5)
- Molecular formula C15H22ClN3O; molecular weight 295.81 g/mol
- Purity ≥ 98.3% (LCMS)
- Supplied as hydrochloride salt, solid form
- Available in milligram pack sizes for research use
- Intended for in vitro and preclinical research; not for human use
Medchemexpress LLC Prostaglandin D2 | 41598-07-6 | MFCD00077857 | 99.5% | 352.47 | C20H32O5 | 1 MG
Prostaglandin D2 (PGD2) is an endogenous eicosanoid involved in sleep regulation and immune/inflammatory signaling. Supplied as a research reagent, this purified compound is intended for in vitro and biochemical studies and is accompanied by safety and analytical documentation for laboratory use.
- High purity (99.5%) suitable for analytical and pharmacological experiments.
- Molecular weight 352.47 and chemical formula C20H32O5.
- Available in small milligram pack sizes for bench-scale research.
- Accompanied by SDS and certificate of analysis to support safe handling and data traceability.
- Commonly used in studies of sleep, inflammation, and prostaglandin signaling pathways.
Medchemexpress LLC 1-Methylguanosine-d3 | 2140-65-0 | 99.5% | 300.29 | 1 MG
1-Methylguanosine-d3 (N1-Methylguanosine-d3) is a deuterium labeled form of 1-Methylguanosine, a methylated nucleoside derived from RNA degradation and identified as a tumour marker. This compound is for research use only.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Cambridge Isotope Laboratories 24R,25-DIHYDROXYVITAMIN D2 UNLABELED, 1 MG
24R,25-DIHYDROXYVITAMIN D2 UNLABELED, 1 MG
Medchemexpress LLC Nudifloramide-d3 | 1207384-48-2 | 99.4% | 155.17 | 1 MG
Nudifloramide-d3 (2PY-d3) is a deuterium labeled Nudifloramide. It is an end product of nicotinamide-adenine dinucleotide (NAD) degradation and significantly inhibits poly(ADP-ribose) polymerase (PARP-1) activity in vitro. Deuteration, the incorporation of stable heavy isotopes, allows it to be used as a tracer during drug development, affecting pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Sigma Aldrich Fine Chemicals Biosciences 1Alpha,25-Dihydroxyvitamin D3 | 32222-06-3 | MFCD00867079 | 0.1mg
1Alpha,25-Dihydroxyvitamin D3 | Purity: 99% | Mol Wt: 416.64 | 32222-06-3 | MFCD00867079 | 0.1mg
Cell Signaling Technology Prostatic Acid Phosphatase (D3Y5P) Rabbit mAb 20 ul
Prostatic Acid Phosphatase (D3Y5P) Rabbit mAb 20 ul