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Also available in 1 mL, 1 mg, 2 mg, 5 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. MBQ-167 is a dual inhibitor of Rac/Cdc42 (IC50s 103 nM for Rac 1/2/3 and 78 nM for Cdc42 in MDA-MB-231 cells, respectively). Purity 98.74%
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meso-Erythritol is a high-purity analytical standard of the sugar alcohol erythritol, provided for research and analytical applications. It occurs naturally in fruits, is about 60-80% as sweet as sucrose, and is supplied as a white crystalline material with confirmed purity suitable for analytical work.
High purity (99.73% by HPLC).
Suitable as an analytical standard for research and quality control.
Soluble in water and DMSO.
Molecular weight 122.12 g/mol; molecular formula C4H10O4.
Applicable as a low-calorie sweetener reference and in biochemical assays.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
MBQ-167 is a dual Rac/Cdc42 inhibitor, with IC50s of 103 nM for Rac 1/2/3 and 78 nM for Cdc42 in MDA-MB-231 cells. It is for research use only.
Dual Rac/Cdc42 inhibitor.
Available in solid and solution forms.
Significantly reduces migration of liver specific Dnmt3a-/- hematopoietic cells at 200 nM (20 h).
Induces a loss of polarity in metastatic breast cancer cells at concentrations ≥100 nM.
Causes ~95% cell rounding and detachment in metastatic MDA-MB-231 cells at 500 nM for 24 h.
Inhibits Rac activity in attached and detached cancer cells.
Induces phenotype in various mesenchymal cancer cell types.
Demonstrates a statistically significant reduction in tumor growth in treated mice, with an ~80% reduction at 1.0 mg/kg BW and ~95% reduction at 10 mg/kg BW.
10 times more effective than EHop-016 in reducing tumor growth in mice.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
meso-erythritol (CAS 149-32-6) is a four-carbon sugar alcohol supplied as a white to off-white solid for research and analytical use. It serves as a low-calorie sweetener reference and an analytical standard in biochemical and chromatography applications, with high reported purity suitable for laboratory studies.
High purity: 99.7%.
White to off-white solid appearance.
Chemical formula C4H10O4 and molecular weight 122.12 g/mol.
Supplied in small laboratory sizes including a 5 g package.
Intended for analytical standards and research applications.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More