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Estrone sulfate potassium is the potassium salt of estrone sulfate, an endogenous estrogen conjugate supplied for laboratory research. It is available as a high-purity solid and as a DMSO solution for in vitro studies, and is intended for research use only.
High purity 99.45%.
Molecular weight 388.52 and formula C18H21KO5S.
Available in multiple sizes, including 5 mg, and as a 10 mM solution in DMSO.
Soluble in DMSO for preparation of stock solutions.
Supplied for research use only; not for human or clinical use.
May be restricted or controlled in some territories.
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nor-NOHA (acetate) (CAS 1140844-63-8) is a potent reversible inhibitor of rat liver arginase (Ki 0 5 M) By competitively inhibiting arginase nor-NOHA modulates the cellular balance between the L-arginine-dependent pathways of nitric oxide synthase (NOS) and arginase affecting nitric oxide production and urea cycle metabolism In vitro studies have shown that nor-NOHA suppresses proliferation migration and invasion of HepG2 hepatocellular carcinoma cells induces apoptosis and alters expression of Arg1 MMP-2 P53 and ECD In vivo nor-NOHA improves endothelial function in rat models of inflammation by enhancing NOS activity increasing EDHF and reducing superoxide anion production This compound is widely used to investigate arginase-related mechanisms in cellular and vascular biology
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Clevidipine butyrate (CAS 167221-71-8) is a rapidly acting dihydropyridine calcium channel antagonist that selectively inhibits L-type calcium channels in vascular smooth muscle This inhibition leads to arterial vasodilation and subsequent reduction in blood pressure In vitro studies demonstrate an IC50 of 7 1 nM at a holding potential of -40 mV indicating high potency for its target Clevidipine butyrate is primarily investigated in the context of perioperative hypertension offering a research tool for evaluating acute blood pressure management and the pharmacodynamics of short-acting calcium channel blockade in vascular systems
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DL-alpha-tocopherol is the synthetic form of vitamin E used as an antioxidant and analytical standard for laboratory research and analytical applications. It has the chemical formula C29H50O2, a molecular weight of 430.71 g/mol, and CAS number 10191-41-0. Supplied in a 100 mg pack for lab-scale use.
Acts as a lipid-soluble antioxidant.
Suitable as an analytical standard for research applications.
Useful in assays that evaluate oxidative stress and lipid protection.
Provided in a small pack size for convenient laboratory handling.
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A bioactive fatty acid; induces apoptosis and necrosis in human prostate cancer LNCaP cells at a rate of 8.8% and 8.1%, respectively; inhibits C. albicans germination (MIC = 9 µM); inhibits osteogenesis in vitro via interference with cytoskeletal rearrangement; prevents RANKL-induced bone loss and osteoclast formation in mice
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Alkynyl palmitic acid (15-hexadecynoic acid) is an ω-alkynylated long-chain fatty acid bearing a terminal alkyne. It is used as a click-chemistry reagent and an alkyl-chain PROTAC linker for bio-conjugation and synthesis workflows.
Chemical formula: C16H28O2.
Molecular weight: 252.39 g/mol.
Cas number: 99208-90-9.
Contains a terminal alkyne for copper-catalyzed azide-alkyne cycloaddition.
Typical applications include PROTAC linker synthesis and bioconjugation.
Available pack size: 5 mg.
Purity: not specified on the manufacturer datasheet.
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An esterified form of linoleic acid; has been found in several types of animal fat biodiesel and biodiesel synthesized from beef tallow, soybean oil, and babassu oil blends; has been used as a substrate to measure the antioxidant activity of β-carotene against free radical-induced lipid peroxidation
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