Lipids and Lipid Derivatives
Medchemexpress LLC Estradiol benzoate | 50-50-0 | 1 G
Estradiol benzoate (β-Estradiol 3-benzoate) is an HBx protein inhibitor that inhibits androgen and hepatitis B virus (HBV) transcription and replication. It also shows antifertility effects, anti-Toxoplasma gondii activity, and can improve memory behavior in Ovariectomy (Ovx) female mice.
- Inhibits HBx protein.
- Suppresses androgen and hepatitis B virus (HBV) transcription and replication.
- Exhibits antifertility effects.
- Shows anti-Toxoplasma gondii activity.
- Improves memory behavior in ovariectomy (Ovx) female mice.
- Reverses lowered uterine weight in Ovx mice.
- Increases number and density of synaptic vesicles.
Enzo Life Sciences U-73343 (5 mg). CAS: 142878-12-4
Inactive analog of U-73122 (BML-ST391) which only slightly inhibits phospholipase C. May be used as a negative control. Alternative name: 1-[6-[[(17beta)-3-Methoxyestra-1,3,5(10)-trien-17-yl]amino]hexyl]-pyrrolidine-2,5-dione. Purity: ≥98% (HPLC). Solubility: Soluble in methylene chloride or chloroform; slightly soluble in DMSO (2mg/ml) or 100% ethanol (1mg/ml); sparingly soluble in aqueous solutions. Long Term Storage: Ambient.
Apexbio Technology LLC Estradiol Benzoate 50-50-0 10mM (in 1mL DMSO)
Estradiol benzoate (50-50-0) is a small-molecule agonist targeting estrogen receptors exhibiting high binding affinity for estrogen receptor alpha (ER ) It is designed to activate ER thereby modulating estrogen-mediated signaling pathways and hormonal regulation processes Estradiol benzoate exerts its biological activity primarily through ER agonism In in vitro assays involving human murine and chicken ER proteins estradiol benzoate demonstrates agonistic activity with an IC50 value ranging between 22 28 nM Based on these pharmacological properties estradiol benzoate holds research potential in studies of ER-mediated signaling endocrine-related diseases receptor-ligand binding analyses pharmacological screening and investigations of estrogen-dependent physiological and pathological conditions
Medchemexpress LLC U-73343 | 142878-12-4 | 99.4% | 466.66 | 10 MG
U-73343, which works as a protonophore, is an inactive analog of U-73122 and can be used as a negative control. It dose-dependently inhibits acid secretion irrespective of the stimulant. U-73122 is a phospholipase C (PLC) and 5-LO (5-lipoxygenase) inhibitor with an IC50 of 1-2.1 μM for PLC.
- Functions as a protonophore
- Can be used as a negative control
- Inhibits acid secretion dose-dependently
Cayman Chemical Estradiol Benzoate
An estradiol analog; often used in combination with a progestin to induce estrus in domestic livestock; binds to human, murine, and chicken ERα IC50s = 22-28 nM)
eMolecules 142878-12-4 | Medchem Express | U-73343 | 5mg | 482203907 | HY-108630 | 466.666 | C29H42N2O3
Ambeed | 57-Dimethyl-N-(trans-4-(pentyloxy)cyclohexyl)pyrazolo[15-a]pyrimidine-3-carboxamide | 1mg | 534567031 | A181720 | 1919820-28-2 | 358.486 | C20H30N4O2
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Sigma Aldrich Fine Chemicals Biosciences U-73122 hydrate powder | 112648-68-7 (anhydrous) | MFCD12910450 | 5MG
U-73122 hydrate powder | Purity: >=97.5% (HPLC) | 112648-68-7 (anhydrous) | MFCD12910450 | 5MG
Medchemexpress LLC Bazedoxifene (acetate)-D | 198481-33-3 | MFCD09260074 | C32H38N2O5 | 100 MG
Bazedoxifene (acetate)-D is a solid compound with a molecular formula of C32H38N2O5 and a molecular weight of 530.65. It is classified as a selective estrogen receptor modulator and a bone density conservation agent. This compound helps to inhibit bone resorption and favor bone mineralization, making it suitable for addressing conditions like osteoporosis and promoting bone fracture healing. It is an FDA-approved, prescription-only drug administered orally.
- Functions as a selective estrogen receptor modulator
- Acts as a bone density conservation agent
- Inhibits bone resorption
- Promotes bone mineralization and regeneration
- Utilized in treating osteoporosis and healing bone fractures
- FDA-approved, available by prescription only
- Administered via oral route
Medchemexpress LLC Bazedoxifene (acetate) | 198481-33-3 | 99.88% | C32H38N2O5 | 500 MG
Bazedoxifene acetate (TSE-424 acetate) is an oral, nonsteroidal selective estrogen receptor modulator (SERM). It has IC50s of 23 nM for ERα and 99 nM for ERβ. This compound is used in the research of osteoporosis. Additionally, Bazedoxifene acetate acts as an inhibitor of IL-6/GP130 protein-protein interactions and is utilized in research for pancreatic cancer.
- Oral, nonsteroidal selective estrogen receptor modulator (SERM)
- Exhibits IC50s of 23 nM for ERα and 99 nM for ERβ
- Used in osteoporosis and pancreatic cancer research
- Inhibits IL-6/GP130 protein-protein interactions and STAT3 phosphorylation
- Induces apoptosis and blocks cell migration in pancreatic cancer cells in vitro
- Inhibits Capan-1 tumor growth in a mouse model in vivo
Medchemexpress LLC Norethisterone enanthate | 3836-23-5 | 99.5% | C27H38O3 | 1 ML
Norethisterone enanthate is a long-acting parenteral progestogen used as an intramuscular contraceptive agent. It is also an orally active click chemistry reagent containing an alkyne group, enabling copper-catalyzed azide-alkyne cycloaddition with azide-containing molecules.
- Long-acting parenteral progestogen
- Functions as an intramuscular contraceptive agent
- Orally active
- Contains an alkyne group for click chemistry applications
- Powder stable at -20°C for 3 years or 4°C for 2 years
- Solution stable at -80°C for 2 years or -20°C for 1 year
- Store stock solutions aliquoted to prevent inactivation from repeated freeze-thaw cycles
Medchemexpress LLC 19-Norpregn-4-en-20-yn-3-one, 17-[(1-oxoheptyl)oxy]-, (17α)- | 3836-23-5 | 99.5% | C27H38O3 | 500 MG
Norethisterone enanthate is a long-acting parenteral progestogen. It is orally active and functions as a click chemistry reagent, containing an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules possessing Azide groups. This product is for research use only and not sold to patients.
- Long-acting parenteral progestogen
- Orally active
- Functions as a click chemistry reagent
- Contains an alkyne group for copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Can be used as an intramuscular contraceptive agent (in vitro)
- Inhibits fertility in female rats (in vivo)
Medchemexpress LLC Chlormadinone acetate | 302-22-7 | 98.0% | 1 ML
Chlormadinone acetate | 302-22-7 | 98.0% | 1 ML
Medchemexpress LLC Bazedoxifene (acetate) | 198481-33-3 | 99.9% | C32H38N2O5 | 50 MG
Bazedoxifene (acetate) is an oral, nonsteroidal selective estrogen receptor modulator (SERM) primarily used in research for osteoporosis and pancreatic cancer. It acts as an inhibitor of IL-6/GP130 protein-protein interactions and shows IC50s of 23 nM and 99 nM for ERα and ERβ respectively. This product is intended for laboratory chemical applications and research use only.
- Oral, nonsteroidal selective estrogen receptor modulator
- Inhibitor of IL-6/GP130 protein-protein interactions
- Suitable for osteoporosis research
- Suitable for pancreatic cancer research
- Available as a white to off-white solid
- Purity of 99.9%
Medchemexpress LLC Bazedoxifene (acetate) | 198481-33-3 | 99.9% | C32H38N2O5 | 25 MG
Bazedoxifene (acetate)-B is the B-crystal form compound of Bazedoxifene acetate. Bazedoxifene acetate is an orally active, nonsteroidal selective estrogen receptor modulator (SERM), with IC50s of 23 nM for ERα and 99 nM for ERβ.
- B-crystal form compound of bazedoxifene acetate
- Orally active nonsteroidal selective estrogen receptor modulator
- IC50s of 23 nM for ERα and 99 nM for ERβ
- Solid appearance
- For research use only
- Stable under recommended storage conditions
Sigma Aldrich Fine Chemicals Biosciences Norethisterone acetate European Pharmacopoeia (EP) Reference Standard | 51-98-9 | MFCD00271615 |
Norethisterone acetate European Pharmacopoeia (EP) Reference Standard | Mol Wt: 340.46 | 51-98-9 | MFCD00271615 |