Nucleosides and Analogues
Medchemexpress LLC 6H-Purin-6-one, 2-amino-1,9-dihydro-9-β-L-ribofuranosyl- | 26578-09-6 | 98.0% | 283.24 | 250 MG
L-Guanosine is the L-configuration of Guanosine. This purine nucleoside exhibits anti-herpesvirus activity and can be used in the preparation of supramolecular hydrogel.
- L-configuration of guanosine
- Purine nucleoside
- Exhibits anti-herpesvirus activity
- Can be used in the preparation of supramolecular hydrogel
- Functions as a nucleoside antimetabolite/analog
- Acts as an inhibitor
Medchemexpress LLC Glucosamine hydrochloride | 66-84-2 | 215.63 | 10 G
Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, used as a dietary supplement. It is also a natural constituent of glycosaminoglycans found in the cartilage matrix and synovial fluid. When administered exogenously, it exhibits pharmacological effects on osteoarthritic cartilage and chondrocytes.
- Purity: 98.0%
- Exhibits dose-dependent DPPH antioxidant activity.
- Short-term treatment inhibits HIF-1α at the protein level, and decreases phosphorylation of p70S6K and S6, which are translation-related proteins.
- Significantly decreases renal expression of α-smooth muscle actin, collagen I, and fibronectin in obstructed kidneys and TGF-β1-treated renal cells.
- Appearance: White to off-white solid.
Medchemexpress LLC 2'-Deoxyadenosine-5'-triphosphate-13C10,15N5 (dilithium) | 1927-31-7 | 99.2% | 517.94 | 1 MG
2'-Deoxyadenosine-5'-triphosphate-13C10,15N5 (dATP-13C10,15N5) dilithium is a 13C and 15N-labeled nucleotide essential for DNA synthesis as a substrate of DNA polymerase. It is valuable in research as:
- Used as a tracer.
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Adenosine 5'-monophosphate monohydrate | 18422-05-4 | 99.8% | C10H16N5O8P | 250 MG
Adenosine 5'-monophosphate monohydrate, also known as 5'-AMP monohydrate, is an adenosine A1 receptor agonist. It has demonstrated significant antiviral activity against both HSV-1 and HSV-2 and is intended for research use only.
- Functions as an adenosine A1 receptor agonist
- Exhibits significant antiviral activity against HSV-1 and HSV-2
- Reduces mRNA expression of TNF-α and IL-6 in RAW264.7 cells
- Attenuates inflammatory responses by reducing NF-κB p65 recruitment
- Increases hepatic adenosine levels in mice
- Improves survival rates and liver health in animal models
- Chemical formula: C10H16N5O8P
- Molecular weight: 365.24
- Appearance: White to off-white solid
Medchemexpress LLC Adenosine 5'-monophosphate (monohydrate) | 18422-05-4 | 98.9% | C10H16N5O8P | 100 MG
Adenosine 5'-monophosphate monohydrate is an analytical standard intended for research and analytical applications. It is commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
- Used as an analytical standard
- Reference standard supplied assay
- Commonly used in qualitative research experiments
- Commonly used in quantitative research experiments
- Commonly used in methodological research experiments
- Suitable for HPLC, GC, and MS applications
- For research use only
Medchemexpress LLC Adenosine monophosphate (Standard) | 61-19-8 | 99.7% | C10H14N5O7P | 250 MG
Adenosine monophosphate (Standard) is the analytical standard for Adenosine monophosphate and is intended for research and analytical applications. It acts as an adenosine A1 receptor agonist, demonstrates significant antiviral activity against HSV-1 and HSV-2, and is a vital cellular metabolite involved in regulating energy homeostasis and signal transduction.
- Analytical standard for research and analytical applications.
- Functions as an adenosine A1 receptor agonist.
- Exhibits significant antiviral activity against HSV-1 and HSV-2.
- Key cellular metabolite for energy homeostasis and signal transduction.
- Commonly used in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS.
Medchemexpress LLC GTP-14564 | 34823-86-4 | 99.9% | 234.25 | 10 MG
GTP-14564 is a tyrosine kinase inhibitor that targets internal tandem duplication (ITD) and FLT3. It inhibits FLT3 ligand-dependent growth in Ba/F3 leukemia cells.
- Tyrosine kinase inhibitor
- Targets ITD and FLT3
- Inhibits FLT3 ligand-dependent growth in Ba/F3 leukemia cells
- Available in various quantities
- Available as solid or in solution (10 mM in DMSO)
- Off-white to yellow solid appearance
- For research use only
- Has a data sheet, COA, SDS, and handling instructions available
Medchemexpress LLC 2'-Deoxyguanosine (standard) | 961-07-9 | MFCD00080300 | 99.2% | 267.24 | 50 MG
2'-Deoxyguanosine (Standard) is the analytical standard for 2'-Deoxyguanosine. It is intended for research and analytical applications. This purine nucleoside exhibits diverse biological activities, including inducing DNA division in mouse thymus cells and acting as a potent cell division inhibitor in plant cells. In vitro, it inhibits the clonal growth of HL-60 and K562 leukemia cells with IC50 values of 50 and 80 μM, respectively.
- Analytical standard for 2'-deoxyguanosine
- Intended for research and analytical applications
- Induces DNA division in mouse thymus cells
- Potent cell division inhibitor in plant cells
- Inhibits clonal growth of HL-60 and K562 leukemia cells
- Used in qualitative, quantitative, and methodological research experiments
- Suitable for HPLC, GC, and MS applications
Medchemexpress LLC BVDU 5′-triphosphate ammonium | 98.0% | 590.11 g/mol | C11H19BrN3O14P3 | 10mg
BVDU 5 -Triphosphate ammonium is an antivirus agent with 5 -Triphosphate label targeting viral DNA polymerase BVDU 5 -Triphosphate ammonium shows excellent selectivity against varicella-zoster virus (VZV) and herpes simplex virus type 1 (HSV-1) due to a specific phosphorylation by the virus-encoded thymidine kinase
Medchemexpress LLC Nicotinamide riboside chloride | 23111-00-4 | MFCD27952781 | 100.0% | 290.70 g/mol | C11H15ClN2O5 | 10MG
Nicotinamide riboside chloride is the chloride salt of nicotinamide riboside, a bioavailable precursor of nicotinamide adenine dinucleotide (NAD+) used in biochemical and cell biology research to elevate cellular NAD+ levels and probe NAD+-dependent pathways. It is supplied as a high-purity, crystalline white to off-white solid suitable for in vitro and analytical applications.
- High purity: 99.97%.
- CAS number: 23111-00-4.
- Molecular formula: C11H15ClN2O5; molecular weight: 290.70 g/mol.
- Chloride salt form for improved stability and handling.
- Suitable for studies that increase cellular NAD+ and investigate metabolic or sirtuin-related pathways.
- Stable solid form for storage and analytical use.
Medchemexpress LLC 2′-deoxyguanosine 5′-monophosphate-13C10,15N5 dilithium | MFCD00080331 | 99.8% | 373.98 g/mol | 13C10H12Li215N5O7P | 5 MG
2′-Deoxyguanosine 5′-monophosphate-13C10,15N5 dilithium is a stable isotope-labeled nucleotide supplied as the dilithium salt for quantitative analytical applications. The 13C and 15N labelling enables accurate tracing and quantitation in mass spectrometry and NMR workflows.