Nucleosides and Analogues
Alkali Scientific 5 Bromo 2' deoxyuridine, 250 Milligrams
Bromo Deoxyuridine (BrdU) is a nucleoside analog used in DNA labeling, supplied in 250mg quantity. BrdU is commonly incorporated into newly synthesized DNA during cell division, allowing researchers to track DNA replication and study cell proliferation. This compound is used in cellular biology and molecular research, particularly in assays that require the monitoring of cell cycle progression. BrdU labeling is a powerful technique for identifying proliferating cells in tissues, and it is widely used in cancer research, immunology, and neurobiology. It is also used for assessing DNA synthesis rates and conducting flow cytometry experiments related to cell division and DNA repair processes.
Medchemexpress LLC 2'-Deoxycytidine-5'-monophosphate | 1032-65-1 | 99.9% | 307.20 | 5 G
2'-Deoxycytidine-5'-monophosphate is an endogenous metabolite and a deoxynucleotide building block of DNA. It can serve as a substrate for UMP/CMP kinase to form dCDP upon phosphorylation to dCTP, thereby supporting DNA biosynthesis.
- Endogenous metabolite
- Deoxynucleotide building block of DNA
- Substrate for UMP/CMP kinase
- Supports DNA biosynthesis
Medchemexpress LLC Deoxycytidine triphosphate-d14 dilithium | 2687960-70-7 | 95.7% | 493.11 g/mol | C9D14Li2N3O13P3 | 10 MG
Deoxycytidine triphosphate-d14 dilithium is a deuterium-labeled nucleoside triphosphate provided as the dilithium salt for use as an isotopic standard or tracer in DNA synthesis workflows, including PCR, sequencing, and analytical method development.
- Deuterium-labeled for isotopic tracing and mass-shift detection.
- Dilithium salt form, compatible with aqueous buffers.
- High purity (~95.7%) suitable for analytical and molecular biology use.
- Supplied in a 10 mg vial for small-scale experiments.
- Useful as a stable labeled standard for qPCR, sequencing, and method validation.
Medchemexpress LLC 2'-Deoxyuridine-1'-13C | 478510-85-9 | 5 MG
2'-Deoxyuridine-1'-13C is a carbon-13 labeled version of 2'-Deoxyuridine. This compound induces chromosome breakage, thereby reducing the synthesis activity of thymidylate. Additionally, it serves as a precursor in the synthesis of Edoxudine.
- Carbon-13 labeled version of 2'-Deoxyuridine.
- Induces chromosome breakage.
- Reduces synthesis activity of thymidylate.
- Serves as a precursor in the synthesis of Edoxudine.
Accela Chembio Inc THYMIDINE | 25G | 50-89-5 | MFCD00006537 | 98% | RETEST PERIOD: 1800DAYS | LIGHT SENSITIVE/+4c
THYMIDINE | 25G | 50-89-5 | MFCD00006537 | 98% | RETEST PERIOD: 1800DAYS | LIGHT SENSITIVE/+4c
Medchemexpress LLC 2'-Deoxycytidine-5'-monophosphate | 1032-65-1 | MFCD00006546 | 99.99% | 307.20 | 100 MG
2'-Deoxycytidine-5'-monophosphate is an endogenous metabolite and a deoxynucleotide building block of DNA. It serves as a substrate for UMP/CMP kinase to form dCDP upon phosphorylation to dCTP, supporting DNA biosynthesis. This compound is intended for research use only and is not sold to patients.
- Endogenous metabolite
- Deoxynucleotide building block of DNA
- Supports DNA biosynthesis
Medchemexpress LLC 2'-Deoxycytidine-5'-monophosphoric acid disodium | 13085-50-2 | 98.0% | 351.16 | 250 MG
2'-Deoxycytidine-5'-monophosphoric acid disodium, also known as dCMP disodium, is an endogenous metabolite. This chemical compound is provided as a solid, white to off-white in appearance, with a purity of 98.0%. It is intended for research use only.
- Endogenous metabolite
- Suitable for research applications
- High purity (98.0%)
Medchemexpress LLC Deoxycytidine 5'-triphosphate, trisodium salt | 109909-44-6 | 99.5% | 533.10 g/mol | C9H13N3Na3O13P3 | 25 MG
Deoxycytidine triphosphate (trisodium) is provided as a ready-to-use 100 mM aqueous solution of the trisodium salt of dCTP. It functions as a nucleotide substrate for DNA synthesis, polymerase reactions, and enzymatic assays, and is supplied as a high-purity solution intended for molecular biology workflows.
- High purity: 99.46% suitable for sensitive assays.
- Ready-to-use 100 mM aqueous solution for immediate use.
- Trisodium salt form enhances solubility in aqueous buffers.
- Colorless to light yellow liquid for easy visual inspection.
- Available in small pack sizes (for example, 25 mg) to reduce waste.
- Storage-stable when frozen; follow manufacturer storage guidance.
Medchemexpress LLC 2'-Deoxycytidine-5'-monophosphoric acid disodium (dCMP disodium) | 13085-50-2 | MFCD00069774 | 98.0% | 351.16 | 500 MG
2'-Deoxycytidine-5'-monophosphoric acid disodium (dCMP disodium) is an endogenous metabolite. This product is intended for research use only and is not for sale to patients.
- Endogenous metabolite
- For research use only
Cambridge Isotope Laboratories 5-Fluoro-2-deoxyuridine 5-triphosphate ammonium salt (unlabeled) (in solution) CP 95% 100 umol
5-Fluoro-2-deoxyuridine 5-triphosphate ammonium salt (unlabeled) (in solution) CP 95% 100 umol
Medchemexpress LLC KTX-951 | 2573298-36-7 | 99.6% | 850.95 | 1 MG
KTX-951 is an orally active PROTAC degrader targeting IRAK4 and IMiD (Ikaros/Aiolos) substrates. It exhibits a Kd of 3.5 nM for IRAK4, with DC50 values of 13 nM, 14 nM, and 13 nM for IRAK4, Ikaros, and Aiolos, respectively. This compound also shows an IC50 of 35 nM for OCl-Ly10 CTG and demonstrates antitumor activity.
- Orally active PROTAC degrader
- Targets IRAK4 and IMiD (Ikaros/Aiolos) substrates
- Kd of 3.5 nM for IRAK4
- Molecular weight: 850.95
- Formula: C46H52F2N8O6
- Appearance: Solid, light yellow to yellow
- Purity: 99.60%
- Soluble in DMSO at 50 mg/mL (58.76 mM)
- Oral bioavailability in rats: 22% at 10 mg/kg
- Oral bioavailability in dogs: 57% at 10 mg/kg
Medchemexpress LLC Uridine, 2'-deoxy-4-thio- | 5580-20-1 | MFCD00058457 | 99.8% | 244.27 g·mol⁻¹ | C9H12N2O4S | 5 MG
4-Thio-2'-deoxyuridine is a sulfur-substituted deoxyuridine nucleoside analog supplied as a light-yellow solid and used as a research reagent in studies of DNA synthesis, nucleoside metabolism, and antitumor mechanisms. It is characterized for biochemical and cell-based experiments and provided with supporting analytical data.
- High purity (99.8%) for research applications.
- Sulfur-substituted nucleoside for incorporation and metabolism studies.
- Stable solid form with recommended low-temperature storage.
- Well-characterized molecular properties (C9H12N2O4S; 244.27 g·mol⁻¹).
- Available in small quantities suitable for laboratory-scale experiments.
Medchemexpress LLC 4-thio-2'-deoxyuridine | 5580-20-1 | MFCD00058457 | 99.8% | 244.27 g/mol | C9H12N2O4S | 100 MG
4-Thio-2'-deoxyuridine is a sulfur-substituted deoxyuridine nucleoside analogue used in biochemical and nucleic acid research, including studies of nucleic acid chemistry and incorporation into oligonucleotides. It has molecular formula C9H12N2O4S, molecular weight 244.27 g/mol, and a reported purity of 99.78%.
- Sulfur-substituted deoxyuridine analogue useful for nucleic acid studies.
- High reported purity (99.8%), suitable for analytical and synthetic applications.
- Available in multiple pack sizes for research-scale work.
- Provided with certificate of analysis and safety data sheet for quality and handling.
- Offered in solid form and as 10 mM DMSO solution for convenient use.
Medchemexpress LLC 2'-Deoxycytidine-5'-monophosphate | 1032-65-1 | 99.99% | 307.20 | 5 MG
2'-Deoxycytidine-5'-monophosphate (2'-Deoxycytidine-5'-monophosphoric acid) is an endogenous metabolite and a deoxynucleotide building block of DNA. It acts as a substrate of UMP/CMP kinase to form dCDP upon phosphorylation to dCTP, thereby supporting DNA biosynthesis.
- Endogenous metabolite
- Deoxynucleotide building block for DNA
- Substrate for UMP/CMP kinase
- Supports DNA biosynthesis
Medchemexpress LLC 2'-Deoxyuridine (standard) | 951-78-0 | 99.2% | 5 MG
2'-Deoxyuridine (Standard) is the analytical standard of 2'-Deoxyuridine, intended for research and analytical applications. It is a brain-penetrant pyrimidines nucleotide associated with nervous system diseases. It can increase chromosome breakage and decrease thymidylate synthetase activity. 2'-Deoxyuridine is a precursor in the synthesis of Edoxudine and an analogue of 5-ethynyl-2'-deoxyuridine, EdU. It reduces microglial activation and improves oxidative stress damage by modulating glycolytic metabolism on Aβ25-35-induced brain injury, making it promising for Alzheimer's disease (AD) research.
- Used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
- Passes the blood-brain barrier (BBB) in mice.
- Improves cognition and memory loss and attenuates hippocampal damage in Aβ25-35-induced mice models.