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Nitrogenous bases covalently linked to a sugar with and without phosphate groups; used for synthesis, cell signaling, and as cofactors in enzymatic reactions; includes pyrimidine, purine, pyridine, flavin, pyrrolopyrimidine, and triazole varieties.
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Uridine is a nucleoside compound composed of uracil and a ribose ring, connected by a β-N1-glycosidic bond. This compound is used for research purposes and has demonstrated various biological activities.
Inhibits the proliferation of HL-60 leukemia cells
Alleviates CCl4-induced liver fibrosis in mice
Shows anti-ischemic, antioxidant, and anti-arrhythmic effects in rat models
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Uridine-13C9 (β-Uridine-13C9) is a 13C9-labeled form of Uridine. Uridine (β-Uridine) is a glycosylated pyrimidine-analog containing uracil attached to a ribose ring (or more specifically, aribofuranose) via a β-N1-glycosidic bond.
This compound can be used as a tracer.
This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
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UDP-glucosamine (UDP-GlcNAc) disodium is a substrate for O-GlcNAc transferase, which facilitates the attachment of O-GlcNAc to proteins. O-GlcNAcase is responsible for removing O-GlcNAc from proteins. This compound is the final product of the hexosamine biosynthesis pathway, primarily controlled by glucose-6-phosphate-Glutamine:fructose-6-phosphate amidotransferase (GFAT).
Substrate for O-GlcNAc transferase
End product of the hexosamine biosynthesis pathway
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Uridine-13C9 (β-Uridine-13C9) is a 13C9-labeled version of Uridine. Uridine is a glycosylated pyrimidine-analog where uracil is attached to a ribose ring through a β-N1-glycosidic bond.
Can be utilized as a tracer.
Can serve as an internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS.
Stable heavy isotopes of elements like hydrogen and carbon are incorporated into drug molecules for quantitation during drug development.
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Uridine (β-Uridine) is a nucleoside compound composed of uracil and a ribose ring, connected by a β-N1-glycosidic bond. It is categorized as a human endogenous metabolite. It offers various biological activities including antiproliferative, anti-fibrotic, and cardioprotective effects.
Inhibits proliferation of leukemia cells and induces differentiation
Alleviates CCl4-induced liver fibrosis by suppressing pro-inflammatory cytokines
Exhibits anti-ischemic, antioxidant, and anti-arrhythmic effects in rat models
Soluble in H2O and DMSO for in vitro applications
Can be prepared in various in vivo dissolution protocols for diverse research needs
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UDP disodium salt (CAS 27821-45-0) is a selective agonist targeting the P2Y6 receptor exhibiting potent stimulatory activity with an EC50 value of approximately 300 nM and a reported pEC50 of 6 52 for the human P2Y6 receptor Endogenously UDP serves as a metabolite involved in catalyzing glucuronidation reactions facilitating the conjugation of glucuronic acid to diverse substrates Due to these biological properties UDP disodium salt finds utility in researching disease-related mechanisms and RNA biosynthesis pathways
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UDP-D-GalNAlk disodium is an alkyne-functionalized UDP-galactose derivative (disodium salt) intended for biochemical research. It functions as a substrate for enzymatic glycosylation and enables bioorthogonal labeling through terminal alkyne click chemistry. The compound is supplied as a solid with high reported purity and should be stored sealed and protected from moisture according to supplier recommendations.
Alkyne-modified UDP-sugar for bioorthogonal labeling.
Serves as substrate for galactosyltransferase and glycosylation assays.
High purity suitable for research applications.
Available in small milligram quantities for lab use.
Stable when stored sealed and kept away from moisture as directed.
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Uridine-5 -diphosphoglucose (UDPG UDP-Glc UDP-D-Glucose UDP- -D-Glucose) activates the P2Y(14) receptor a neuroimmune system GPCR Uridine-5 -diphosphoglucose is the precursor of glucose-containing oligosaccharides polysaccharides glycoproteins and glycolipids in animal tissues and in some microorganisms
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D-Glucosamine 6-phosphate is the 6-phosphorylated form of D-glucosamine and is used as an analytical and biochemical standard for studies of amino-sugar metabolism, glycosaminoglycan biosynthesis, enzymatic assays, and metabolomics. It is provided as a high-purity compound for laboratory research applications.
High purity suitable for analytical applications.
Useful as a reference standard for LC-MS and HPLC.
Compatible with enzymatic and kinetic assays.
Supplied in small milligram quantities for laboratory use.
Molecular weight 259.15 g/mol; chemical formula C6H14NO8P.
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Chemical. CAS 137868-52-1. Formula C15H22N2Na2O17P2. MW 610.27. Uridine 5-diphospho-alpha-D-galactose UDP-Gal is a nucleotide sugar. UDP-Gal is a donor substrate for galactosyltransferases used in the biosynthesis of galactose-containing oligosaccharides. UDP-Gal has been used as a component in galactosyltransferase labeling buffer to prelabel terminal N-acetylglucosamine GlcNAc on immunoglobulin chains. It has also been used as a component in Hyp O-galactosyltransferase HPGT assay. Decreased red blood cell levels of UDP-Gal are found in patients with maple syrup urine disease or phenylketonuria.
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