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ATP (Adenosine-5 -triphosphate) known as in Chinese is a fundamental component for energy transfer in biological systems ATP and its sodium salts can be utilized in numerous molecular biology applications such as kinase reactions in vitro transcription ligation reactions and phosphorylation assays This product is a colorless transparent aqueous solution prepared from ATP trisodium salt with a purity 99% (by HPLC) concentration of 100 mM pH (25 ) 7 0 0 1 and free of DNase RNase and phosphatase contamination
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GTP also known as Guanosine-5 -triphosphate can be utilized in various molecular biology applications such as in vitro transcription RNA amplification and siRNA synthesis Additionally GTP plays a critical regulatory role in signal transduction as a phosphate or pyrophosphate messenger it activates G-proteins which subsequently initiate protein kinase-mediated signaling cascades thus influencing cellular behaviors including cell proliferation and differentiation GTP also serves as a high-energy nucleotide precursor participating in enzymatic synthesis processes of DNA and RNA This product is prepared from GTP trisodium salt with purity 99% (HPLC) as a clear colorless aqueous solution at a concentration of 100 mM and pH (25 C) of 7 0 0 1 free from DNase and RNase contamination
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Adenosine 5'-monophosphate (AMP) is a nucleotide involved in cellular energy transfer and signal transduction. This research-grade biochemical is supplied as a solid or solution and is intended for in vitro research applications; the manufacturer lists high purity and molecular weight of 347.22 g/mol.
High purity (99.8%) suitable for research use
Defined molecular weight of 347.22 g/mol
Available as solid and as DMSO solution for flexible use
Commonly used in biochemical assays and receptor pharmacology studies
Provided with supporting documentation such as datasheets and COA when available
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Peonidin-3-O-arabinoside chloride is an anthocyanin chloride salt isolated from Vaccinium myrtillus L. It is provided as a high-purity solid for biochemical and pharmacological research, suitable for analytical assays and small-scale experimental use.
Purity 98.5%.
Chemical formula C21H21ClO10.
Molecular weight 468.84 g/mol.
Physical form solid.
Supplied in milligram-scale quantities for research use.
Natural source documented from Vaccinium myrtillus L.
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Motesanib Diphosphate (AMG-706 CAS 857876-30-3) is an oral small-molecule ATP-competitive inhibitor that targets vascular endothelial growth factor receptors (VEGFR1/2/3) platelet-derived growth factor receptor (PDGFR) c-Kit and Ret with reported IC50 values of 2 84 nM It demonstrates over 1000-fold selectivity for VEGFRs relative to EGFR Src and p38 kinases In vitro Motesanib Diphosphate potently inhibits VEGF-induced proliferation of human endothelial cells (IC50 10 nM) and blocks PDGF- and SCF-induced signaling while showing minimal effects on bFGF-stimulated proliferation In preclinical studies it suppresses angiogenesis and induces regression in tumor xenograft models Motesanib is under investigation in anti-angiogenic cancer research
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Motesanib Diphosphate (AMG-706 CAS 857876-30-3) is an oral small-molecule ATP-competitive inhibitor that targets vascular endothelial growth factor receptors (VEGFR1/2/3) platelet-derived growth factor receptor (PDGFR) c-Kit and Ret with reported IC50 values of 2 84 nM It demonstrates over 1000-fold selectivity for VEGFRs relative to EGFR Src and p38 kinases In vitro Motesanib Diphosphate potently inhibits VEGF-induced proliferation of human endothelial cells (IC50 10 nM) and blocks PDGF- and SCF-induced signaling while showing minimal effects on bFGF-stimulated proliferation In preclinical studies it suppresses angiogenesis and induces regression in tumor xenograft models Motesanib is under investigation in anti-angiogenic cancer research
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5-Bromo-2 -deoxyuridine (5-BrdU CAS 59-14-3) is a thymidine analog that integrates into DNA during S-phase of cell division Its incorporation facilitates immunodetection via specific monoclonal or polyclonal antibodies In vitro studies show that early application of 5-BrdU to Nicotiana glauca pith explants inhibits cellular proliferation an effect reversed by addition of thymidine or deoxycytidine In vivo BrdU immunostaining identifies proliferating neuronal cells in mouse central nervous system tissues paralleling earlier thymidine labeling studies Thus 5-BrdU serves as a molecular tool for analyzing cell cycle progression and neurogenesis in biomedical research
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