Nucleosides and Analogues
Medchemexpress LLC Flavin adenine dinucleotide (disodium salt) | 84366-81-4 | 99.7% | 50 MG
Flavin adenine dinucleotide (FAD) disodium salt is a redox cofactor, more specifically a prosthetic group of a protein. It is involved in several important enzymatic reactions in metabolism, making it crucial for various biological processes.
- Functions as a redox cofactor
- Acts as a prosthetic group for proteins
- Participates in key enzymatic reactions in metabolism
- Targeted as an endogenous metabolite
- Relevant in metabolic enzyme and protease pathways
- Applied in COVID-19 immunoregulation research
- Used in cardiovascular disease research
Medchemexpress LLC L-Guanosine | 26578-09-6 | 98.0% | 283.24 | 25 MG
L-Guanosine is the L-configuration of Guanosine. It is a purine nucleoside that exhibits anti-herpesvirus activity and can be used to prepare supramolecular hydrogel. This product ships at room temperature and should be stored solid at 4°C, protected from light. Solutions can be stored at -80°C for 6 months or -20°C for 1 month, also protected from light.
- Purine nucleoside
- Exhibits anti-herpesvirus activity
- Can be used to prepare supramolecular hydrogel
- Ships at room temperature
- Solid storage: 4°C, protect from light
- In solvent storage: -80°C for 6 months or -20°C for 1 month, protect from light
Medchemexpress LLC 2'-Deoxyguanosine 5'-monophosphate disodium hydrate | 146877-98-7 | 99.0% | C10H14N5O7.H2O.2Na | 100 MG
2'-Deoxyguanosine 5'-monophosphate disodium hydrate (dGMP) is an oxidizable target of the photosensitizer pterin. It can be used to evaluate the photosensitizing properties of biopterins. Pterin causes a photosensitive reaction of dGMP under UV-A radiation, leading to DNA damage. This process involves two main mechanisms in vitro for the photosensitive oxidation of purine nucleotides by pterin.
- A hydrogen abstraction reaction of electron transfer from dGMP to the triplet excited state of pterin (type I mechanism).
- Interaction between dGMP and pterin produces singlet molecular oxygen (1O2) (type II mechanism).
Medchemexpress LLC 2'-Deoxyguanosine monohydrate | 312693-72-4 | 99.7% | 10 G
2'-Deoxyguanosine monohydrate is a nucleoside composed of guanine and 2'-deoxyribose, and it is one of the basic structural units of DNA. The oxidation products of 2'-Deoxyguanosine monohydrate may participate in DNA damage, which in turn may affect gene expression or induce cancer.
- Composed of guanine and 2'-deoxyribose.
- Basic structural unit of DNA.
- Oxidation products may participate in DNA damage.
- Can affect gene expression or induce cancer.
- High purity of 99.70%.
- Ships at room temperature.
- Store solid at 4°C, sealed, away from moisture.
- Store in solvent at -80°C for 6 months or -20°C for 1 month, sealed, away from moisture.
Sigma Aldrich Fine Chemicals Biosciences Adenosine 5 monophosphate25G
REAGENT Adenosine 5 monophosphate25G
Apexbio Technology LLC Primaquine Diphosphate 63-45-6 10mM (in 1mL DMSO)
Primaquine Diphosphate is an 8-aminoquinoline derivative utilized primarily as an antimalarial agent targeting the extraerythrocytic liver stage of malaria parasites While its precise IC50 values remain unspecified primaquine s biological activity involves interference with nucleic acid function subsequently disrupting protein synthesis pathways and lipid biosynthesis and inducing membrane disturbances In vitro primaquine has been applied in cell culture models to investigate antiviral effects demonstrating dose-dependent inhibition of Newcastle disease virus replication and modulation of viral RNA synthesis In vivo experiments using radiolabeled primaquine-loaded liposomes in murine models illustrate pronounced hepatic accumulation Clinically this compound is employed as prophylaxis against malaria infections (e g Plasmodium falciparum and P vivax)
Medchemexpress LLC Adenosine 5'-(trihydrogen diphosphate), compd. with cyclohexanamine (1:2) | 102029-87-8 | 99.9% | 250 MG
Adenosine 5'-diphosphate (dicyclohexylammonium) is a high-purity chemical compound, confirmed by HPLC at 99.92%. It features a molecular formula of C22H41N7O10P2 and a molecular weight of 625.55. This compound is typically a white to off-white solid.
- High purity (99.92% by HPLC)
- White to off-white solid appearance
- Consistent with chemical structure (1H NMR and MS)
- Molecular formula: C22H41N7O10P2
- Molecular weight: 625.55
- Recommended storage conditions: -20°C, protect from light
Medchemexpress LLC Adenosine receptor antagonist 2 | 2703054-47-9 | 99.4% | C23H21FN8O | 100 MG
Adenosine receptor antagonist 2 is an orally active A2a/A2b adenosine receptor antagonist. It exhibits anti-tumor activity by inhibiting tumor growth in vivo. This compound is characterized by its potent inhibitory concentrations for both A2a and A2b adenosine receptors.
- Orally active A2a/A2b adenosine receptor antagonist
- IC50 of 1 nM for A2a adenosine receptor
- IC50 of 3 nM for A2b adenosine receptor
- Exhibits anti-tumor activity
- Inhibits tumor growth in female C57BL/6 mice
- Demonstrates specific pharmacokinetic profiles in mice studies
Medchemexpress LLC BRM/BRG1 ATP Inhibitor-2 | 2368900-77-8 | 99.7% | C20H20N4O2S2 | 500 MG
BRM/BRG1 ATP Inhibitor-2 is a BRG1/BRM ATPase inhibitor used for the research of BAF-related disorders. It is intended for research use only and is not sold to patients. The compound has a molecular weight of 412.53 and appears as a white to off-white solid. It is soluble in DMSO at 100 mg/mL.
- Used for the research of BAF-related disorders
- Appears as a white to off-white solid
- Soluble in DMSO at 100 mg/mL
- Stock solutions can be stored at -80°C for 6 months or -20°C for 1 month
Cayman Chemical 5-chloro-5-DeoxyadenosIn 10g
A nucleoside analog used as a substrate in the biosynthesis of the anticancer agent salinosporamide A
Medchemexpress LLC β-Uridine (Standard) | 58-96-8 | MFCD00006526 | 99.90% | 50 G
Uridine (β-Uridine) is a nucleoside compound composed of uracil and a ribose ring, which are connected by a β-N1-glycosidic bond. It has a molecular formula of C9H12N2O6 and a molecular weight of 244.20. It appears as a white to off-white solid. This product is for research use only and has not been fully validated for medical applications.
- A nucleoside compound
- Composed of uracil and a ribose ring
- Connected by a β-N1-glycosidic bond
- Molecular formula: C9H12N2O6
- Molecular weight: 244.20
- Appearance: white to off-white solid
- Storage: store at room temperature for 3 years
- In solvent, store at -80°C for 2 years or -20°C for 1 year
- For research use only
Medchemexpress LLC D-Glucosamine (sulfate) | 29031-19-4 | 277.25 | 500 MG
Glucosamine sulfate (D-Glucosamine sulfate) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids. It is used as a dietary supplement and is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, which, when administered exogenously, exerts pharmacological effects on osteoarthritic cartilage and chondrocytes.
- Used as a dietary supplement.
- Exerts pharmacological effects on osteoarthritic cartilage and chondrocytes.
- Exhibits dose-dependent DPPH antioxidant activity.
- Short-term treatment inhibits HIF-1α at the protein level, decreasing phosphorylation of p70S6K and S6, translation-related proteins.
- Significantly decreases renal expression of α-smooth muscle actin, collagen I, and fibronectin in obstructed kidneys and TGF-β1-treated renal cells.
- Purity of 98.0%.
![eMolecules 58-96-8 | Uridine | AA Blocks LLC | MFCD00006526 | 244.203 | C9H12N2O6 | 0.000 | OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O | 5g | 443397313](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000163550.jpg-250.jpg)
eMolecules 58-96-8 | Uridine | AA Blocks LLC | MFCD00006526 | 244.203 | C9H12N2O6 | 0.000 | OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O | 5g | 443397313
Uridine | AA Blocks LLC | 58-96-8 | MFCD00006526 | 244.203 | C9H12N2O6 | 0.000 | OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O | 5g | 443397313
Medchemexpress LLC Uridine-5'-diphosphoglucose pyrophosphorylase | 9026-22-6 | MFCD00132561 | 500 U
Uridine-5'-diphosphoglucose pyrophosphorylase is an enzyme involved in the catalysis of UDP-glucose synthesis. It can be used to determine the concentration of pyrophosphate in urine.
- Catalyzes UDP-glucose synthesis
- Utilized in pyrophosphate concentration determination
- Classified as an enzyme
- Glycobiology enzyme
- Recombinant
- Metabolic enzyme/protease