Nucleosides and Analogues
Apexbio Technology LLC GTP-Binding Protein Fragment, G alpha 10mg
GTP-Binding Protein Fragment G alpha is a peptide fragment derived from the amino-terminal region of the alpha subunit of GTP-binding proteins It is designed to aid in elucidating the mechanisms of membrane association and -subunit interactions in cell signaling pathways GTP-Binding Protein Fragment G alpha exerts its biological activity by retaining membrane-binding properties independent of the nucleotide-binding state anchoring the protein to the cytoplasmic membrane surface This peptide fragment serves as an experimental tool to study membrane-association mechanisms and signal transduction pathways in biochemical and biomedical research Based on these properties GTP-Binding Protein Fragment G alpha holds research potential in investigating the molecular basis of G protein-mediated signal transduction and protein-membrane interactions
Apexbio Technology LLC GTP-Binding Protein Fragment, G alpha 25mg
GTP-Binding Protein Fragment G alpha is a peptide fragment derived from the amino-terminal region of the alpha subunit of GTP-binding proteins It is designed to aid in elucidating the mechanisms of membrane association and -subunit interactions in cell signaling pathways GTP-Binding Protein Fragment G alpha exerts its biological activity by retaining membrane-binding properties independent of the nucleotide-binding state anchoring the protein to the cytoplasmic membrane surface This peptide fragment serves as an experimental tool to study membrane-association mechanisms and signal transduction pathways in biochemical and biomedical research Based on these properties GTP-Binding Protein Fragment G alpha holds research potential in investigating the molecular basis of G protein-mediated signal transduction and protein-membrane interactions
Sigma Aldrich Fine Chemicals Biosciences Guanosine 5 betagama imi100MG
Guanosine 5prime-[beta gamma-imido]triphosphate (GMP-PNP Gpp(NH)p) is a non-hydrolyzable analog of GTP that binds and irreversibly activates G proteins. Gpp(NH)p is used in a variety of applications that involve GTP binding including GTP-activation GTP-inhibition GTP transport GTP hydrolysis and GTP structure stabilization. Since a cycle of GTP binding hydrolysis and release is required for the initiation of protein translocation across the endoplasmic reticulum guanosine 5prime-[beta gamma-imido]triphosphate is often used in studies of protein synthesis. Gpp(NH)p is used to activate ADP-ribosylation factors and to modulate G proteins involved in cell signaling protein synthesis and other metabolic processes.
Innovative Research Inc Imprtn A2 RcmbPrtn N6 Htag
Human Importin alpha 2 Recombinant Protein N-6 His Tag 50UG - Human Importin alpha 2 Recombinant Protein N-6 His Tag is produced in E. coli. This is a Liquid protein buffered in a 0.2 um filtered solution of 20mM TrisHCl,1mM DTT,20% Glycerol, pH 8.0 . It is not recommended to reconstitute to a concentration less than 100UG/ml. with a purity of greater than 95% per reducing SDS-PAGE.Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.Karyopherin Subunit alpha-2 (KPNA2) belongs to the importin alpha family. KPNA2 is widely expressed in many tissues and contains an N-terminal hydrophilic region, a hydrophobic central region composed of 10 repeats, and a short hydrophilic C-terminal. KPNA2 interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins. KPNA2 also may play a role in V(D)J recombination.KPNA2 functions in nuclear protein importantly as an adapter protein for nuclear receptor KPNB1 For RUO.
Medchemexpress LLC Nicotinamide N-Methy 100ug | 100ug
The nicotinamide N-methyltransferase (NNMT) protein catalyzes the methylation of nicotinamide using S-adenosyl-L-methionine to form N1-methylnicotinamide NNMT affects pluripotent embryonic stem cell development and acts as a metabolic regulator affecting adipose tissue energy expenditure gluconeogenesis and cholesterol biosynthesis Nicotinamide N-Methyltransferase/NNMT Protein Human (His) is the recombinant human-derived Nicotinamide N-Methyltransferase/NNMT protein expressed by E coli with C-His labeled tag
Medchemexpress LLC Nicotinamide N-Methy 50ug | 50ug
The nicotinamide N-methyltransferase (NNMT) protein catalyzes the methylation of nicotinamide using S-adenosyl-L-methionine to form N1-methylnicotinamide NNMT affects pluripotent embryonic stem cell development and acts as a metabolic regulator affecting adipose tissue energy expenditure gluconeogenesis and cholesterol biosynthesis Nicotinamide N-Methyltransferase/NNMT Protein Human (His) is the recombinant human-derived Nicotinamide N-Methyltransferase/NNMT protein expressed by E coli with C-His labeled tag
Medchemexpress LLC D-(+)-glucosamine hydrochloride | 66-84-2 | 215.63 | 50 MG
Glucosamine hydrochloride is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, also used as a dietary supplement. It is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, exerting pharmacological effects on osteoarthritic cartilage and chondrocytes. This product exhibits dose-dependent DPPH antioxidant activity and inhibits HIF-1α at the protein level.
- Exerts pharmacological effects on osteoarthritic cartilage and chondrocytes.
- Exhibits dose-dependent DPPH antioxidant activity.
- Inhibits HIF-1α at the protein level.
- Decreases phosphorylation of p70S6K and S6, translation-related proteins.
- Decreases renal expression of α-smooth muscle actin, collagen I, and fibronectin in obstructed kidneys and TGF-β1-treated renal cells.
Medchemexpress LLC Flavin adenine dinucleotide disodium salt | 84366-81-4 | MFCD00005041 | 99.72% | 500 UG
Flavin adenine dinucleotide (FAD) disodium salt is a redox cofactor, specifically a prosthetic group of a protein, that participates in several important enzymatic reactions in metabolism. It is for research use only.
- Redox cofactor
- Prosthetic group of a protein
- Involved in several important enzymatic reactions in metabolism
Medchemexpress LLC Guanosine 5'-triphosphate trisodium salt hydrate | 207300-85-4 | 95.0% | 100 MG
Guanosine 5'-triphosphate trisodium salt hydrate is an activator of the signal transducing G proteins and serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA.
- Activator of signal transducing G proteins
- Energy-rich precursor in DNA and RNA biosynthesis
- For research use only
Selleck Chemical LLC FAD disodium salt-E0705-5MG
Flavin Adenine Dinucleotide Disodium is a redox cofactor more specifically a prosthetic group of a protein involved in several important enzymatic reactions in metabolism
Medchemexpress LLC 8-azidoadenosine 5'-triphosphate trisodium | 00-00-0 | 98.1% | 614.14 | C10H12N8Na3O13P3 | 5 MG
8-Azido-ATP trisodium is a photoreactive adenosine triphosphate analog supplied as the trisodium salt in solution. It is used to photo-crosslink and label ATP-binding proteins and serves as an azide-containing reagent for click chemistry and protein-nucleotide interaction studies.
- Photoreactive ATP analog for photo-crosslinking and protein identification.
- Azide functionality enables copper-catalyzed and strain-promoted click chemistry.
- Supplied as trisodium salt in a solution form suitable for direct use or dilution.
- High reported purity, supporting reproducible experimental results.
- Storage guidelines support frozen stock solutions for long-term stability.
Medchemexpress LLC Glucosamine (sulfate) | 29031-19-4 | 277.25 | 100 MG
Glucosamine sulfate is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, used as a dietary supplement. It is also a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, which, when administered exogenously, exerts pharmacological effects on osteoarthritic cartilage and chondrocytes.
- Exhibits dose-dependent DPPH antioxidant activity.
- Inhibits HIF-1α at the protein level with short-term treatment.
- Decreases phosphorylation of p70S6K and S6, translation-related proteins.
- Significantly decreases renal expression of α-smooth muscle actin, collagen I, and fibronectin in obstructed kidneys and TGF-β1-treated renal cells.
Medchemexpress LLC 8-azidoadenosine 5'-triphosphate trisodium | 00-00-0 | 98.1% | C10H12N8Na3O13P3 | 10MG
8-Azido-ATP trisodium is a photoreactive adenosine triphosphate analog used for photoaffinity labeling and identification of ATP-binding proteins and nucleotide-interacting enzymes. Supplied as the trisodium salt with high purity (98.1%), it is intended for research applications involving UV-activated crosslinking to probe protein-nucleotide interactions.
- Photoreactive azido group enables UV-activated crosslinking to binding partners.
- Suitable for identifying ATP-binding proteins and nucleotide-interacting enzymes.
- Available as the water-soluble trisodium salt for aqueous assays.
- High purity suitable for analytical and biological experiments.
- Compatible with downstream identification techniques such as SDS-PAGE and mass spectrometry.
![Medchemexpress LLC Uridine 5'-(trihydrogen diphosphate), P'-[2-(acetylamino)-2-deoxy-α-D-glucopyranosyl] ester, sodium salt (1:2) | 91183-98-1 | 99.92% | 651.32 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000440056-Logo.png-250.jpg){kind=logo}
Medchemexpress LLC Uridine 5'-(trihydrogen diphosphate), P'-[2-(acetylamino)-2-deoxy-α-D-glucopyranosyl] ester, sodium salt (1:2) | 91183-98-1 | 99.92% | 651.32 | 25 MG
UDP-GlcNAc Disodium Salt is a donor substrate of O-GlcNAc transferase (OGT). OGT is a nucleocytoplasmic glycosyltransferase that modifies thousands of proteins by adding a unique N-acetylglucosamine residue onto acceptor substrates mainly confined within the cytosol and nucleus.
- Donor substrate of O-GlcNAc transferase (OGT).
- Modifies thousands of proteins by adding a unique N-acetylglucosamine residue.
- For research use only.
Medchemexpress LLC Glucosamine hydrochloride | 66-84-2 | 215.63 | 10 G
Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, used as a dietary supplement. It is also a natural constituent of glycosaminoglycans found in the cartilage matrix and synovial fluid. When administered exogenously, it exhibits pharmacological effects on osteoarthritic cartilage and chondrocytes.
- Purity: 98.0%
- Exhibits dose-dependent DPPH antioxidant activity.
- Short-term treatment inhibits HIF-1α at the protein level, and decreases phosphorylation of p70S6K and S6, which are translation-related proteins.
- Significantly decreases renal expression of α-smooth muscle actin, collagen I, and fibronectin in obstructed kidneys and TGF-β1-treated renal cells.
- Appearance: White to off-white solid.