Chromatography Standards
Cayman Chemical 4'-hydroxy Flurbiprofen, Purity: ≥95%, CAS: 52807-12-2, 10 mg
A major active metabolite of flurbiprofen, (R)-flurbiprofen, and (S)-flurbiprofen; inhibits COX-1 by 94% at 1,000 µM but does not inhibit oxygenation of arachidonic acid; completely inhibits cyclooxygenation of 2-AG at 300 µM; inhibits FAAH hydrolysis of anandamide in rat brain homogenates (IC50 = 84 µM at a pH of 6)
Selleck Chemical LLC Mifepristone 50mg 84371-65-3 RU486, C-1073
Mifepristone (RU486, C-1073) is a remarkably active antagonist of progesterone receptor and glucocorticoid receptor with IC50 of 0.2 nM and 2.6 nM, respectively. Mifepristone promotes cell autophagy and apoptosis, decreases Bcl-2 level and increases Beclin1 level, accompanied by weakened interaction between Bcl-2 and Beclin1. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Medchemexpress LLC Dacomitinib impurity 12 | 2803451-99-0 | 10mg
Dacomitinib impurity 12 is an impurity of Dacomitinib (HY-13272)
Medchemexpress LLC Dacomitinib impurity 8 | 2119689-75-5 | 10mg
Dacomitinib impurity 8 is an impurity of Dacomitinib (HY-13272)
Medchemexpress LLC Insulin glargine | 160337-95-1 | ≥95.0% | 6062.89 | 100 MG
Insulin glargine is a long-acting insulin analog. It lowers blood sugar and is used in diabetes research. High doses have also been shown to promote the proliferation of bladder cancer cells.
- Long-acting insulin analog
- Lowers blood sugar
- Used in diabetes research
Cayman Chemical 5-Bromotetralone, Purity: ≥98%, CAS: 68449-30-9, 500 mg
A synthetic intermediate useful for pharmaceutical synthesis.
Sigma Aldrich Fine Chemicals Biosciences Norfloxacin Related Compound K United States Pharmacopeia (USP) Reference Standard | 70459-07-3 | 15MG
Norfloxacin Related Compound K United States Pharmacopeia (USP) Reference Standard | Mol Wt: 305.3 | 70459-07-3 | 15MG
Sigma Aldrich Fine Chemicals Biosciences Methylprednisolone acetate for system suitability European Pharmacopoeia (EP) Reference Standard | 53-36-1 |
Methylprednisolone acetate for system suitability European Pharmacopoeia (EP) Reference Standard | Mol Wt: 416.51 | 53-36-1 |
Apexbio Technology LLC Cefditoren Pivoxil 117467-28-4 100mg
Cefditoren pivoxil is a small-molecule prodrug antibiotic targeting penicillin-binding proteins It is designed to inhibit these proteins thereby disrupting peptidoglycan cross-linking essential for bacterial cell wall integrity Cefditoren pivoxil exerts its biological activity primarily through inhibition of bacterial cell wall synthesis This mechanism confers bactericidal activity against a broad range of Gram-positive and Gram-negative organisms Based on these pharmacological properties cefditoren pivoxil holds research potential in studying bacterial susceptibility profiles characterizing resistance mechanisms in pathogens and evaluating pharmacokinetic-pharmacodynamic relationships associated with cephalosporins
Medchemexpress LLC Tenofovir alafenamide | 379270-37-8 | MFCD23843796 | C21H29N6O5P | 1 ML
Tenofovir alafenamide (GS-7340) is an investigational oral proagent of Tenofovir, functioning as an HIV-1 nucleotide reverse transcriptase inhibitor. It is intended for research use only.
- Investigational oral proagent of Tenofovir
- Functions as an HIV-1 nucleotide reverse transcriptase inhibitor
- Exhibits antiviral activity against HIV-1 and HIV-2 isolates
- Effective in PBMCs with EC50s ranging from 0.1 to 12 nM for HIV-1 isolates
- Soluble in DMSO (≥ 31 mg/mL) and H2O (6.67 mg/mL with ultrasonication)
Medchemexpress LLC CPD-1224 | 2891620-68-9 | C43H47ClN8O7S | 100 MG
CPD-1224 is an orally effective ALK inhibitor derived from an ALK inhibitor that connects to the cereblon ligand. It targets the EML4-ALK oncogenic fusion protein, leading to the degradation of both ALK and its mutant forms L1196M/G1202R. This compound has the potential to slow down tumor growth and is for research use only.
- Enhances kinase binding selectivity and exhibits good degradation selectivity
- Shows antiproliferative activity against mouse Ba/F3 cells
- Demonstrates oral bioavailability of 28% in mice (10 mg/kg, oral)
- Inhibits tumor growth in mice by reducing total ALK and phosphorylated ALK levels
Medchemexpress LLC l-Naproxen | 23979-41-1 | MFCD00870716 | C14H14O3 | 200 MG
l-Naproxen, also known as (R)-Naproxen, is an enantiomer of (S)-Naproxen with demonstrated anti-tumor activity. It acts as a nonsteroidal anti-inflammatory agent (NSAID) and selectively inhibits the activity of Cdc42 and Rac1. In vitro studies highlight its ability to inhibit the migration of immortalized human ovarian cancer cells through a COX-independent mechanism.
- Inhibits Cdc42 and Rac1 activity
- Exhibits anti-tumor properties
- Functions as a nonsteroidal anti-inflammatory agent
- Selectively inhibits Rac1 and Cdc42 in HeLa cells
- Inhibits migration of human ovarian cancer cells
- Operates via a COX-independent mechanism
Medchemexpress LLC Ketoconazole | 65277-42-1 | 99.57% | C26H28Cl2N4O4 | 1 ML
Ketoconazole | 65277-42-1 | 99.57% | C26H28Cl2N4O4 | 1 ML
Medchemexpress LLC (rel)-Tivantinib | 905853-99-8 | 96.5% | C23H19N3O2 | 100 MG
(rel)-Tivantinib is a potent and highly selective inhibitor of the receptor tyrosine kinase c-MET. It also targets GSK3α and GSK3β, which are important in the cellular mechanism of non-small cell lung cancer (NSCLC).
- Potent and highly selective inhibitor of c-MET
- Targets GSK3α and GSK3β
Biotang Inc Irbesartan, (Avapro) > 99%, 10MG, CAS#138402-11-6, M.W.428.53, SYON:BMS-186295, SR-47436. RI004-10MG
Irbesartan, (Avapro) > 99%, 10MG, CAS#138402-11-6, M.W.428.53, SYON:BMS-186295, SR-47436. RI004-10MG.