Organometallic Compounds
Medchemexpress LLC Tri(amino-PEG5-amide)-amine | 2055013-52-8 | 99.9% | C45H93N7O18 | 25 MG
Tri(amino-PEG5-amide)-amine is a PEG-based PROTAC linker. It is used in the synthesis of PROTACs, which are molecules designed to selectively degrade target proteins by exploiting the intracellular ubiquitin-proteasome system.
- PEG-based PROTAC linker
- Can be used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- For research use only
Medchemexpress LLC Bcn-peg3-oh | 2126749-77-5 | 99.6% | 369.45 | C19H31NO6 | 10 MG
BCN-PEG3-OH is a BCN-functionalized PEG linker used as a non-cleavable linker and click-chemistry reagent for bioconjugation and antibody-drug conjugate synthesis. It features a BCN group for copper-free strain-promoted alkyne-azide cycloaddition (SPAAC) and a three-unit PEG spacer terminating in a hydroxyl group.
- Non-cleavable PEG linker for ADC synthesis
- BCN group enables strain-promoted alkyne-azide cycloaddition (SPAAC)
- Three-unit PEG spacer with terminal hydroxyl
- High purity suitable for research applications
- Available in small pack sizes for laboratory use
![Medchemexpress LLC Propanoic acid, 3-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester | 186020-66-6 | 95.0% | 278.34 g/mol | C13H26O6 | 25 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000202875.png-250.jpg)
Medchemexpress LLC Propanoic acid, 3-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester | 186020-66-6 | 95.0% | 278.34 g/mol | C13H26O6 | 25 G
Hydroxy-PEG3-(CH2)2-Boc is a Boc-protected, hydroxy-terminated polyethylene glycol linker used as a building block in linker and PROTAC synthesis. Supplied as a white to off-white solid, it has a typical purity of 95.0% and a molecular weight of 278.34 g/mol (CAS 186020-66-6).
- Boc-protected hydroxy-terminated PEG3 linker for synthetic chemistry.
- Typical purity 95.0% by NMR.
- Molecular weight 278.34 g/mol.
- Chemical formula C13H26O6.
- Supplied as a 25 g package for laboratory research use only.
Medchemexpress LLC N-Boc-PEG5-bromide | 1392499-32-9 | MFCD31536756 | 98.0% | 400.31 g/mol | C15H30BrNO6 | 1 G
N-Boc-PEG5-bromide is a Boc-protected polyethylene glycol (PEG5) bromide linker reagent used in organic synthesis for assembling antibody-drug conjugate (ADC) and proteolysis-targeting chimera (PROTAC) linkers. It supplies a protected amine and a reactive terminal bromide for nucleophilic substitution and coupling reactions, and is provided at high purity for research use.
- Provides a Boc-protected amine for temporary protection during synthesis.
- Offers a terminal bromide suitable for nucleophilic substitution and coupling reactions.
- PEG5 spacer increases solubility and flexibility in linker constructs.
- High purity appropriate for research and linker assembly.
- Stable under recommended storage conditions for extended shelf life.
Medchemexpress LLC m-PEG3-succinimidyl carbonate | 477775-77-2 | 99.4% | C12H19NO8 | 100 MG
m-PEG3-succinimidyl carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Contains two different ligands connected by a linker
- One ligand for an E3 ubiquitin ligase
- The other ligand for the target protein
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
eMolecules 1872262-73-1 | Ambeed | 1-(tert-Butyl) 4-(13-dioxoisoindolin-2-yl) piperidine-14-dicarboxylate | 250mg | 714083294 | A1496205 | 374.393 | C19H22N2O6
Medchem Express | Mepazine (hydrochloride) | 25mg | 536983959 | HY-121282A | 2975-36-2 | 346.920 | C19H23ClN2S
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Medchemexpress LLC Azido-PEG5-triethoxysilane | 3025193-22-7 | MFCD31693730 | 95.0% | C22H46N4O9Si | 25 MG
Azido-PEG5-triethoxysilane is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent due to its Azide group, which allows it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules containing Alkyne groups. Additionally, it can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Used in the synthesis of PROTACs.
- Functions as a click chemistry reagent.
- Contains an Azide group for copper-catalyzed azide-alkyne cycloaddition reactions.
- Can undergo strain-promoted alkyne-azide cycloaddition reactions.
- PROTACs enable selective degradation of target proteins via the intracellular ubiquitin-proteasome system.
Medchemexpress LLC m-PEG3-azide | 74654-06-1 | MFCD00020141 | >98% | C7H15N3O3 | 250 MG
m-PEG3-azide is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent due to its Azide group, enabling it to participate in various cycloaddition reactions.
- Participates in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with alkyne groups.
- Can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups.
Sigma Aldrich Fine Chemicals Biosciences Diethylzinc solution 15 wt800G
Diethylzinc solution 15 wt800G
TARGETMOL CHEMICALS INC LJP-1586 HCL 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. LJP-1586 HCl a highly selective inhibitor of vascular adhesion protein-1 (VAP-1) exhibits antiinflammation effect by reducing adhesion molecule expression and immune cell infiltration after intracerebral hemorrhage (ICH). purity: 99%
Medchemexpress LLC 2-(2-(2-Bromoethoxy)ethoxy)ethyl methanesulfonate | 2702323-73-5 | 95.0% | 291.16 | 100 MG
Br-PEG3-MS is a PEG-based PROTAC linker employed in the synthesis of PROTACs. These molecules feature two distinct ligands connected by a linker, one targeting an E3 ubiquitin ligase and the other a target protein. PROTACs leverage the intracellular ubiquitin-proteasome system to achieve selective degradation of target proteins. This product is intended for research use only.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the ubiquitin-proteasome system
- Selectively degrades target proteins
- For research use only