Organometallic Compounds
Medchemexpress LLC N-(Amino-PEG3)-N-bis(PEG4-Boc) | 2353409-57-9 | MFCD29267156 | >98% | C38H77NO17 | 50 MG
N-(Amino-PEG3)-N-bis(PEG4-Boc) is a building block and PEG linker used to synthesize various PEG-based linkers. It can easily react with activated NHS esters or carboxylic acid in the presence of EDC or HATU. The t-butyl group can be deprotected under acidic conditions, and it is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
- Easily reacts with activated NHS esters or carboxylic acid in the presence of EDC or HATU.
- t-butyl group can be deprotected under acidic conditions.
- Functions as a PEG-based PROTAC linker.
Medchemexpress LLC Bcn-peg3-oh | 2126749-77-5 | 99.6% | 369.45 | C19H31NO6 | 10 MG
BCN-PEG3-OH is a BCN-functionalized PEG linker used as a non-cleavable linker and click-chemistry reagent for bioconjugation and antibody-drug conjugate synthesis. It features a BCN group for copper-free strain-promoted alkyne-azide cycloaddition (SPAAC) and a three-unit PEG spacer terminating in a hydroxyl group.
- Non-cleavable PEG linker for ADC synthesis
- BCN group enables strain-promoted alkyne-azide cycloaddition (SPAAC)
- Three-unit PEG spacer with terminal hydroxyl
- High purity suitable for research applications
- Available in small pack sizes for laboratory use
![Medchemexpress LLC 5,8,11-Trioxa-2-azatridecanoic acid, 13-hydroxy-, (1α,8α,9ẞ)-bicyclo[6.1.0]non-4-yn-9-ylmethyl ester | 2126749-77-5 | 99.6% | 369.45 g/mol | C19H31NO6 | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000202514.png-250.jpg)
Medchemexpress LLC 5,8,11-Trioxa-2-azatridecanoic acid, 13-hydroxy-, (1α,8α,9ẞ)-bicyclo[6.1.0]non-4-yn-9-ylmethyl ester | 2126749-77-5 | 99.6% | 369.45 g/mol | C19H31NO6 | 50 MG
BCN-PEG3-OH is a BCN-functionalized PEG linker intended for bioconjugation and antibody-drug conjugate (ADC) synthesis. The reagent contains a bicyclo[6.1.0]nonyne (BCN) group that reacts with azides via strain-promoted alkyne-azide cycloaddition (SPAAC), enabling copper-free click chemistry in aqueous conditions.
- Non-cleavable four-unit PEG linker suitable for ADC construction.
- Enables strain-promoted alkyne-azide cycloaddition with azide-functionalized molecules.
- High reported purity for reliable conjugation performance.
- Available in multiple pack sizes, including small research quantities.
Medchemexpress LLC Azido-PEG3-SSPy | 98.6% | 344.45 g/mol | C13H20N4O3S2 | 25 MG
Azido-PEG3-SSPy is a cleavable three-unit polyethylene glycol (PEG) linker containing an azide functional group, designed for bioconjugation and antibody-drug conjugate (ADC) synthesis. It enables click chemistry (CuAAC) and strain-promoted azide-alkyne cycloadditions (SPAAC) for attachment to alkyne- or DBCO/BCN-containing molecules.
- Cleavable disulfide-containing PEG linker suitable for ADC construction.
- Azide-functionalized for copper-catalyzed azide-alkyne cycloaddition (CuAAC).
- Compatible with strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN.
- Supplied as a colorless to light yellow liquid with high purity.
- Suitable for bioconjugation and linker development in drug conjugates.
Medchemexpress LLC Tos-PEG3-CH2COOtBu | 1530778-24-5 | 418.50 | 5 G
Tos-PEG3-CH2COOtBu is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs are molecules designed with two different ligands connected by a linker, one for an E3 ubiquitin ligase and another for the target protein, exploiting the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC Folate-PEG3-C2-acid | 97.6% | C28H36N8O10 | 1 MG
Folate-PEG3-C2-acid is a specialized acid fragment derived from Folate-PEG3-NHS ester, designed as a PEG-type PROTAC linker. This compound is crucial for the synthesis of PROTAC (PROteolysis TArgeting Chimera) molecules, which are heterobifunctional molecules that induce the degradation of target proteins. Its molecular structure facilitates the creation of complex PROTACs, enabling advanced research in targeted protein degradation.
- PEG-type PROTAC linker
- Acid fragment of Folate-PEG3-NHS ester
- Essential for synthesizing PROTAC molecules
- Purity of 97.56% ensures reliable experimental results
Medchemexpress LLC Methyl N-(tert-butoxycarbonyl)-O-methyl-L-serinate | 134167-07-0 | MFCD18837831 | >95.0% | 233.26 g/mol | C10H19NO5 | 5 G
Methyl N-(tert-butoxycarbonyl)-O-methyl-L-serinate is an N-Boc protected serine methyl ester used as an intermediate and building block in organic synthesis and biochemical research. It is supplied for research use only.
- N-Boc protected serine derivative useful as a building block for peptide and small-molecule synthesis.
- O-methylated side chain enables selective functionalization of the serine hydroxyl position.
- Available in multiple pack sizes for lab-scale synthesis and method development.
- Stable under standard laboratory storage conditions; store as recommended on safety documentation.
Medchemexpress LLC L-Carnitine tartrat 25g
L-Carnitine tartrate is a highly polar small zwitterion L-Carnitine tartrate is an essential co-factor for the mitochondrial -oxidation pathway L-Carnitine tartrate functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by -oxidation L-Carnitine tartrate is an antioxidant L-Carnitine tartrate can ameliorate metabolic imbalances in many inborn errors of metabolism[1][2][3]
Medchemexpress LLC N-(Azido-PEG3)-N-Biotin-PEG4-methyl ester | 2100306-76-9 | 95.0% | C30H54N6O11S | 100 MG
N-(Azido-PEG3)-N-Biotin-PEG4-methyl ester is a PEG-based PROTAC linker for the synthesis of PROTACs. It also functions as a click chemistry reagent, facilitating reactions with various alkyne-containing, DBCO, or BCN molecules.
- PEG-based PROTAC linker
- Utilized in PROTAC synthesis
- Functions as a click chemistry reagent
- Contains an azide group
- Enables copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc)
- Supports strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
Medchemexpress LLC Turofexorate isopropyl | 629664-81-9 | 99.8% | C25H24F2N2O3 | 1 ML
Turofexorate isopropyl (FXR-450) is a potent, selective, and orally bioavailable FXR agonist with an EC50 of 4 nM. It is intended for research and analytical applications, and an analytical standard is also available.
- Potent, selective, and orally bioavailable FXR agonist
- Used in autophagy, metabolic disease, and cancer research
- Consistent with structure via 1H NMR and MS
- High purity of 99.8%