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Organometallic Compounds

Organometallic compounds contain direct bonds between carbon atoms and metal atoms/ions and play roles as homogeneous catalysts and stoichiometric reagents in reactions; available in various chemical compositions, quantities, purities, and reagent grades.
Organo-Metalloid Compounds (26)
Organogermanium (3)
Organolithium (3)
Organozinc (1)

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1

Sigma Aldrich 3-Isopropyl-5-[(2S)-2-pyrrolidinyl]-1,2,4-oxadiazole hydrochloride

MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.

ENCOMPASS ENCOMPASS_PREFERRED
2

Sigma Aldrich Ethyl 5-amino-1-isopropyl-1H-pyrazole-4-carboxylate

MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.

ENCOMPASS ENCOMPASS_PREFERRED
3

Germanium(IV) isopropoxide, 99.9% (metals basis)

CAS: 21154-48-3 Molecular Formula: C12H28GeO4 Molecular Weight (g/mol): 308.982 MDL Number: MFCD00015339 InChI Key: PKLMYPSYVKAPOX-UHFFFAOYSA-N Synonym: germanium iv isopropoxide,tetraisopropoxygermane,germanium tetrapropan-2-olate,tetraisopropoxy-germane,tetraisopropoxygermanium,isopropyl germanate iv,germanium tetraisopropoxide PubChem CID: 16685043 IUPAC Name: tetra(propan-2-yloxy)germane SMILES: CC(C)O[Ge](OC(C)C)(OC(C)C)OC(C)C

PubChem CID 16685043
CAS 21154-48-3
Molecular Weight (g/mol) 308.982
MDL Number MFCD00015339
SMILES CC(C)O[Ge](OC(C)C)(OC(C)C)OC(C)C
Synonym germanium iv isopropoxide,tetraisopropoxygermane,germanium tetrapropan-2-olate,tetraisopropoxy-germane,tetraisopropoxygermanium,isopropyl germanate iv,germanium tetraisopropoxide
IUPAC Name tetra(propan-2-yloxy)germane
InChI Key PKLMYPSYVKAPOX-UHFFFAOYSA-N
Molecular Formula C12H28GeO4
4

Isopropyldimethylchlorosilane, 95%

CAS: 3634-56-8 Molecular Formula: C5H13ClSi Molecular Weight (g/mol): 136.69 MDL Number: MFCD00009917 InChI Key: YCXVDEMHEKQQCI-UHFFFAOYSA-N Synonym: isopropyldimethylchlorosilane,dimethylisopropylchlorosilane,chloro isopropyl dimethylsilane,chloro dimethyl isopropylsilane,chlorodimethylisopropylsilane,silane,chlorodimethyl 1-methylethyl,silane, chlorodimethyl 1-methylethyl,dmipscl,acmc-1bn7i,chlorodimethyl isopropylsilane PubChem CID: 5102883 IUPAC Name: chloro-dimethyl-propan-2-ylsilane SMILES: CC(C)[Si](C)(C)Cl

PubChem CID 5102883
CAS 3634-56-8
Molecular Weight (g/mol) 136.69
MDL Number MFCD00009917
SMILES CC(C)[Si](C)(C)Cl
Synonym isopropyldimethylchlorosilane,dimethylisopropylchlorosilane,chloro isopropyl dimethylsilane,chloro dimethyl isopropylsilane,chlorodimethylisopropylsilane,silane,chlorodimethyl 1-methylethyl,silane, chlorodimethyl 1-methylethyl,dmipscl,acmc-1bn7i,chlorodimethyl isopropylsilane
IUPAC Name chloro-dimethyl-propan-2-ylsilane
InChI Key YCXVDEMHEKQQCI-UHFFFAOYSA-N
Molecular Formula C5H13ClSi
5

Dimethylisopropylchlorosilane 90.0+%, TCI America™

CAS: 3634-56-8 Molecular Formula: C5H13ClSi Molecular Weight (g/mol): 136.69 MDL Number: MFCD00009917 InChI Key: YCXVDEMHEKQQCI-UHFFFAOYSA-N Synonym: isopropyldimethylchlorosilane,dimethylisopropylchlorosilane,chloro isopropyl dimethylsilane,chloro dimethyl isopropylsilane,chlorodimethylisopropylsilane,silane,chlorodimethyl 1-methylethyl,silane, chlorodimethyl 1-methylethyl,dmipscl,acmc-1bn7i,chlorodimethyl isopropylsilane PubChem CID: 5102883 IUPAC Name: chlorodimethyl(propan-2-yl)silane SMILES: CC(C)[Si](C)(C)Cl

PubChem CID 5102883
CAS 3634-56-8
Molecular Weight (g/mol) 136.69
MDL Number MFCD00009917
SMILES CC(C)[Si](C)(C)Cl
Synonym isopropyldimethylchlorosilane,dimethylisopropylchlorosilane,chloro isopropyl dimethylsilane,chloro dimethyl isopropylsilane,chlorodimethylisopropylsilane,silane,chlorodimethyl 1-methylethyl,silane, chlorodimethyl 1-methylethyl,dmipscl,acmc-1bn7i,chlorodimethyl isopropylsilane
IUPAC Name chlorodimethyl(propan-2-yl)silane
InChI Key YCXVDEMHEKQQCI-UHFFFAOYSA-N
Molecular Formula C5H13ClSi
6

Allyloxytrimethylsilane 97.0+%, TCI America™

CAS: 18146-00-4 Molecular Formula: C6H14OSi Molecular Weight (g/mol): 130.262 MDL Number: MFCD00008643 InChI Key: MNMVKGDEKPPREK-UHFFFAOYSA-N Synonym: allyloxytrimethylsilane,allyl trimethylsilyl ether,silane, trimethyl 2-propenyloxy,trimethyl 2-propenyloxy silane,o-trimethylsilylallyl alcohol,trimethylallyloxysilane,allyloxy trimethylsilane,silane, trimethyl 2-propen-1-yloxy,trimethyl prop-2-en-1-yloxy silane,acmc-1boq9 PubChem CID: 87471 IUPAC Name: trimethyl(prop-2-enoxy)silane SMILES: C[Si](C)(C)OCC=C

PubChem CID 87471
CAS 18146-00-4
Molecular Weight (g/mol) 130.262
MDL Number MFCD00008643
SMILES C[Si](C)(C)OCC=C
Synonym allyloxytrimethylsilane,allyl trimethylsilyl ether,silane, trimethyl 2-propenyloxy,trimethyl 2-propenyloxy silane,o-trimethylsilylallyl alcohol,trimethylallyloxysilane,allyloxy trimethylsilane,silane, trimethyl 2-propen-1-yloxy,trimethyl prop-2-en-1-yloxy silane,acmc-1boq9
IUPAC Name trimethyl(prop-2-enoxy)silane
InChI Key MNMVKGDEKPPREK-UHFFFAOYSA-N
Molecular Formula C6H14OSi
7

Medchemexpress LLC Turofexorate isopropyl | 629664-81-9 | 99.8% | C25H24F2N2O3 | 1 ML
SDP

Turofexorate isopropyl (FXR-450) is a potent, selective, and orally bioavailable FXR agonist with an EC50 of 4 nM. It is intended for research and analytical applications, and an analytical standard is also available.

  • Potent, selective, and orally bioavailable FXR agonist
  • Used in autophagy, metabolic disease, and cancer research
  • Consistent with structure via 1H NMR and MS
  • High purity of 99.8%

ENCOMPASS_PREFERRED
8

Medchemexpress LLC Turofexorate isopropyl | 629664-81-9 | 99.8% | C25H24F2N2O3 | 50 MG
SDP

Turofexorate isopropyl, also known as FXR-450, is a potent, selective, and orally bioavailable FXR agonist. It exhibits an EC50 of 4 nM and is stable under recommended storage conditions. This product is suitable for various laboratory and research applications, particularly in studies related to metabolic disease and cancer.

  • Potent, selective, and orally bioavailable FXR agonist
  • Features an EC50 of 4 nM
  • Stable under recommended storage conditions
  • High purity of 99.77% as determined by HPLC
  • Consistent with structure based on ¹H NMR spectrum and MS data
  • Applicable in metabolic disease and cancer research

ENCOMPASS_PREFERRED
9

Medchemexpress LLC Turofexorate isopropyl | 629664-81-9 | 99.8% | C25H24F2N2O3 | 25 MG
SDP

Turofexorate isopropyl is a highly potent, selective, and orally bioavailable agonist of the Farnesoid X Receptor (FXR).

  • Acts as an agonist for the Farnesoid X Receptor (FXR).
  • Exhibits significant potency with an EC50 of 4 nM.
  • Characterized by its selective action on FXR.
  • Orally bioavailable, making it suitable for certain research applications.
  • Utilized in research contexts related to Autophagy, Metabolic Disease, and Cancer.
  • Primarily intended for research and analytical applications.

ENCOMPASS_PREFERRED
10

Medchemexpress LLC Azido-PEG5-alcohol | 86770-68-5 | ≥97.0% | 263.29 | C10H21N3O5 | 10 G
SDP

Azido-PEG5-alcohol is a polyethylene glycol (PEG) linker bearing a terminal azide and a terminal hydroxyl group. It functions as a non-cleavable, five-unit PEG spacer for bioconjugation and click chemistry applications.

  • Contains azide (-N3) and terminal alcohol (-OH) functional groups.
  • Water-soluble PEG linker suitable for click chemistry and PROTAC/ADC assembly.
  • Molecular weight ~263.29 g/mol; formula C10H21N3O5.
  • High purity, typically ≥97.0% by manufacturer specification.
  • Available in multiple pack sizes, including 10 g.

ENCOMPASS_PREFERRED
11

Medchemexpress LLC Azido-PEG5-alcohol | 86770-68-5 | >97.0% | 263.29 g·mol⁻¹ | C10H21N3O5 | 5 G
SDP

Azido-PEG5-alcohol is an azide-terminated polyethylene glycol linker containing five ethylene glycol units and a terminal primary alcohol, used as a water-soluble reagent for bioconjugation and linker synthesis. It is commonly applied in click chemistry and in the construction of antibody-drug conjugates and PROTACs.

  • Azide functionality enables CuAAC and SPAAC click reactions.
  • Water-soluble PEG5 spacer improves solubility and flexibility.
  • Terminal primary alcohol provides a synthetic handle for derivatization.
  • Suitable for ADC linker synthesis and PROTAC construction.
  • Supplied as a solid with reported purity >97.0%.

ENCOMPASS_PREFERRED
12

Medchemexpress LLC Azido-PEG5-alcohol | 86770-68-5 | >97.0% | 263.29 g/mol | C10H21N3O5 | 25 G
SDP

Azido-PEG5-alcohol is an azide-terminated polyethylene glycol (PEG) linker containing five ethylene glycol units that is used as a click-chemistry reagent and as a linker in bioconjugation workflows. It participates in copper-catalyzed and strain-promoted azide-alkyne cycloaddition reactions and is supplied for research use only.

  • Azide functional group for click chemistry
  • Five-unit PEG spacer adds hydrophilicity and flexibility
  • Suitable for antibody-drug conjugate and PROTAC linker synthesis
  • Characterized by NMR and LC-MS, purity >97.0%
  • Available in multiple package sizes, including 25 G

ENCOMPASS_PREFERRED
13

Medchemexpress LLC N-(Boc-PEG3)-N-bis(PEG2-alcohol) | 2055042-60-7 | C25H52N2O11 | 50 MG
SDP

N-(Boc-PEG3)-N-bis(PEG2-alcohol) is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs are compounds that contain two different ligands connected by a linker; one ligand is for an E3 ubiquitin ligase and the other is for the target protein. They exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

  • PEG-based PROTAC linker
  • Used in the synthesis of PROTACs
  • Exploits the intracellular ubiquitin-proteasome system
  • Selectively degrades target proteins

ENCOMPASS_PREFERRED
14

Medchemexpress LLC N-(Boc-PEG3)-N-bis(PEG2-alcohol) | 2055042-60-7 | C25H52N2O11 | 250 MG
SDP

N-(Boc-PEG3)-N-bis(PEG2-alcohol) is a PEG-based PROTAC linker used in the synthesis of Proteolysis Targeting Chimeras (PROTACs). PROTACs are designed to leverage the intracellular ubiquitin-proteasome system for the selective degradation of target proteins. This product is intended for research use only.

  • PEG-based PROTAC linker
  • Used in the synthesis of PROTACs
  • Enables targeted protein degradation via the ubiquitin-proteasome system
  • Facilitates connection between an E3 ubiquitin ligase ligand and a target protein ligand

ENCOMPASS_PREFERRED
15

Medchemexpress LLC Azido-PEG5-alcohol | 86770-68-5 | MFCD20134131 | >97.0% | 263.29 g/mol | C10H21N3O5 | 250 MG
SDP

Azido-PEG5-alcohol is a 5-unit polyethylene glycol (PEG) linker bearing an azide and a terminal hydroxyl group, used as a click-chemistry reagent and as a non-cleavable PEG spacer in conjugation and PROTAC synthesis. Purity is ≥97.0%, molecular weight is 263.29 g/mol, and CAS number is 86770-68-5.

  • Enables copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions.
  • Compatible with strain-promoted azide-alkyne cycloaddition (SPAAC) with DBCO or BCN.
  • Non-cleavable 5-unit PEG spacer to improve solubility and flexibility.
  • Available in multiple sizes, including 250 mg.
  • High purity suitable for synthetic and conjugation applications.

ENCOMPASS_PREFERRED