Glycosyl compounds
Apexbio Technology LLC Anti-Amyloid-Beta-Ab-Donanemab
Anti-Amyloid Beta Antibody (Donanemab) (CAS No 1931944-80-7) is a monoclonal antibody under investigation in the field of neurodegenerative research specifically for Alzheimer s disease Originating from biotechnology developments its primary mechanism involves targeting amyloid beta plaques which are believed to contribute to Alzheimer s pathology It binds to a specific epitope on deposited amyloid plaques promoting clearance and reducing their accumulation Common in vitro activity has been observed in the nanomolar to low micromolar range Typical applications include use in cell models animal studies and drug screening assays to assess efficacy and mechanistic pathways Experimental concentrations typically depend on the specific research design
Medchemexpress LLC CD8 beta Human HEK 100ug
CD8 beta is an important immune glycoprotein that serves as a coreceptor for MHC class I peptide complexes linking T cells to antigens presented by APCs It interacts with TCR and MHC class I recruits LCK kinase and initiates multiple signaling pathways CD8 beta Protein Human (HEK293) is the recombinant human-derived CD8 beta protein expressed by HEK293 with tag free
Medchemexpress LLC IFN-beta Human CHO 50ug
IFN-beta is a secretory cytokine produced by cells under viral infection or nucleic acid stimulation IFN binds to cell surface heterodimeric receptors (IFNAR1/IFNAR2) activates the JAK-STAT signaling pathway and induces the expression of interferon-stimulated genes (ISGs) (such as PKR 2 5 -OAS) IFN-beta inhibits viral proliferation regulates immune responses (such as inhibiting Th1 cell polarization reducing pro-inflammatory cytokine secretion) inhibits the proliferation of vascular smooth muscle cells and tumor cells IFN-beta has anti-atherosclerotic and vascular remodeling effects IFN-beta Protein Human (CHO) is a recombinant interferon-beta protein (CHO) expressed by CHO without a tag
Medchemexpress LLC Helicin | 618-65-5 | 10 MG
Helicin is a chemical compound found in Rosaceae, characterized as a moderate syrB inducer. It can be hydrolyzed by the BglY enzyme. This product is intended for research use only.
- Moderate syrB inducer
- Hydrolyzable by BglY enzyme
- Purity: 99.95%
- Molecular weight: 284.26
- Chemical formula: C13H16O7
- Appearance: Solid
- Color: White to off-white
- Storage (powder): -20°C for 3 years, 4°C for 2 years
- Storage (in solvent): -80°C for 6 months, -20°C for 1 month