Monosaccharides
Medchemexpress LLC Lometrexol disodium | 120408-07-3 | 98.0% | C21H23N5Na2O6 | 1 MG
Lometrexol disodium is an antipurine antifolate that inhibits glycinamide ribonucleotide formyltransferase (GARFT) and human Serine hydroxymethyltransferase1/2 (hSHMT1/2). This leads to the inhibition of de novo purine synthesis, causing abnormal cell proliferation, apoptosis, and cell cycle arrest, thus exhibiting anticancer activity.
- Inhibits purine synthesis.
- Induces cell apoptosis.
- Causes cell cycle arrest.
- Demonstrates anticancer properties.
Medchemexpress LLC Crocetin disodium | 591230-99-8 | MFCD22572782 | 99.3% | 372.37 g/mol | C20H22Na2O4 | 10 MG
Crocetin disodium is the disodium salt of crocetin, a carotenoid extracted from saffron (Crocus sativus L.). It acts as an ionotropic glutamate (iGluR) antagonist with high affinity for NMDA receptors and is supplied for in vitro research use.
- Acts as an NMDA (iGluR) receptor antagonist with high affinity.
- High purity, reported as 99.3%.
- Chemical formula C20H22Na2O4; molecular weight 372.37 g/mol.
- Orange to reddish-brown solid; also available as an aqueous solution (10 mM, 1 mL).
- Soluble in water (≥ 4.56 mg/mL, ~12.25 mM); insoluble or slightly soluble in DMSO (< 1 mg/mL).
- Intended for in vitro research applications.
Medchemexpress LLC USP7 ligand-linker conjugate 1 | 10 MG
USP7 Ligand-Linker Conjugates 1 is a ligand-linker conjugate intended as a building block for PROTAC synthesis that targets USP7. It links a USP7-binding ligand to a PROTAC-compatible linker to enable recruitment of E3 ligases and subsequent target degradation. Supplied for research use in medicinal chemistry and chemical biology under appropriate laboratory conditions.
- Designed for PROTAC synthesis targeting USP7.
- Combines a USP7-binding ligand with a PROTAC-compatible linker to recruit E3 ligases.
- Molecular formula C38H49N5O6; molecular weight 671.83.
- Supplied in small research quantities for chemical biology and medicinal chemistry.
- Store pure material at -20°C for long-term stability; see datasheet for solvent storage guidance.
Medchemexpress LLC cGAMP disodium | 2407516-83-8 | 98.5% | 718.37 | 25 MG
cGAMP disodium | 2407516-83-8 | 98.5% | 718.37 | 25 MG
Selleck Chemical LLC Disodium Cromoglycate S1911-1g
Disodium Cromoglycate (Gynazole FPL 670 (Cromolyn) Disodium Cromolyn sodium) is an antiallergic drug with IC50 of 39 g/mL
TARGETMOL CHEMICALS INC Pemetrexed disodium 500MG
Also available in 1 g, 1 mL, 25 mg, 50 mg, 100 mg, 200 mg and bulk. Please contact Fisher for quotes. Pemetrexed disodium (LY-231514) is a parenterally administered folate antagonist and antineoplastic agent, used in the treatment of non-small cell lung cancer and malignant mesothelioma. Pemetrexed disodium therapy has been associated with moderate rates of serum enzyme elevations during therapy, but has not been convincingly linked to instances of acute, clinically apparent liver injury. Purity 99.92%
Selleck Chemical LLC Pemetrexed Disodium Hydrate
Pemetrexed Disodium Hydrate (LY-231514) is a novel antifolate and antimetabolite for TS DHFR and GARFT with Ki of 1 3 nM 7 2 nM and 65 nM respectively Pemetrexed Disodium Hydrate stimulates autophagy and apoptosis
Medchemexpress LLC Lobenzarit disodium 10mg | 64808-48-6 | 10MG
Lobenzarit disodium (CCA) is an anti-arthritic and anti-oxidative agent[1
Medchemexpress LLC Fludarabine (phosphate) | 75607-67-9 | 99.8% | 365.21 | 10 MG
Fludarabine phosphate is an analogue of adenosine and deoxyadenosine, which is able to compete with dATP for incorporation into DNA and inhibit DNA synthesis. This product is for research use only.
- Mimics natural building blocks of DNA
- Interferes with normal DNA synthesis
- Inhibits DNA synthesis
- Shows anticancer activity against various human cell lines
- Significantly reduces cell viability in a dose-dependent manner in vitro
- Leads to complete regressions of tumors and cures in mice in vivo
Medchemexpress LLC Glucose-6-phosphate dehydrogenase | 9001-40-5 | 108.6 kDa | 1KU
Glucose-6-phosphate dehydrogenase is the rate-limiting enzyme of the pentose phosphate pathway, provided as a solid enzyme preparation from microorganisms for biochemical research and enzymatic assays involving NADPH generation and oxidative stress pathways.
- Appearance: White to off-white solid.
- CAS number: 9001-40-5.
- Size: 1 KU.
- Enzyme activity: ≥150 U/mg (solid).
- Specific activity: ≥500 U/mg (protein).
- Molecular weight: 108.6 kDa.
- Optimal pH: 7.0-9.0.
- Unit definition: One unit oxidizes 1 μmol D-glucose-6-phosphate per minute at pH 7.8 and 37°C.
- Storage and shipping: Room temperature shipping in continental US; follow certificate of analysis for storage conditions.
Medchemexpress LLC Cuda disodium | 98.0% | 386.48 g/mol | C19H36N2Na2O3 | 5 MG
CUDA disodium is a potent, research-use small molecule inhibitor of soluble epoxide hydrolase (sEH) that modulates PPARα activity. Reported IC50 values are 11.1 nM (mouse sEH) and 112 nM (human sEH). Supplied as a 5 mg sample with 98.0% purity, it is intended for biochemical and pharmacological research in lipid metabolism and cardiovascular disease models.
- Potent sEH inhibition with reported IC50s of 11.1 nM (mouse) and 112 nM (human).
- Enhances peroxisome proliferator-activated receptor alpha activity in cellular models.
- High purity (98.0%) suitable for biochemical assays.
- Small quantity packaging (5 mg) for screening and early-stage studies.
- Storage recommendations provided for stability in solvent and dry conditions.
Medchemexpress LLC D-Glucose-13C6 | 110187-42-3 | 99.9% | 5 G
D-Glucose-13C6 is a stable isotope-labeled counterpart of D-glucose (HY-B0389). It can be used as a metabolic tracer to track glucose-related synthetic catabolism, or as a synthesis ingredient, minimal media reagent, and internal standard. It is for research use only.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC L-Glucose | 921-60-8 | 99.89% | 180.16 | 25 G
L-Glucose is a stereoisomer of D-Glucose that does not readily enter the brain. It can promote food intake and is used in research to enhance memory in mice. When combined with a fluorescence detector, L-Glucose can produce a fluorescent probe for visualizing and characterizing cancer cells. This product is for research use only and not sold to patients.
- Promotes food intake
- Used to enhance memory in mice
- Can be combined with a fluorescence detector to create a fluorescent probe for visualizing and characterizing cancer cells
Alkali Scientific D (+) Mannose, 1 Kilograms
D (+) Mannose is a high-purity monosaccharide commonly used in laboratory applications related to cell biology and biochemistry. Packaged in a 1 Kg container, this sugar plays a key role in studies involving glycosylation, glycoproteins, and cellular recognition. Mannose is also widely used in cell culture media, enzyme assays, and in research focused on immune responses and disease models. The high purity of this product ensures reliable and reproducible results, making it an essential reagent for applications in immunology, microbiology, and pharmaceutical research.