Sugar acids and derivatives
Medchemexpress LLC Integrin alpha V bet 5ug
Integrin V beta 3 proteins specifically the -V (ITGAV) subunit are multifunctional receptors for ligands such as vitronectin and fibronectin and recognize RGD sequences ITGAV ITGB3 binds fractalkine and acts as a coreceptor in CX3CR1-dependent signaling Integrin alpha V beta 3 Protein Human (HEK293 C-His) is a recombinant protein dimer complex containing human-derived Integrin alpha V beta 3 protein expressed by HEK293 with C-10 His labeled tag Integrin alpha V beta 3 Protein Human (HEK293 C-His) has molecular weight of 90 31 110-150 kDa respectively
Medchemexpress LLC Integrin alpha V bet 100ug | 100ug
Integrin alpha V beta 6 Protein Human (HEK293 His) is a recombinant protein dimer complex containing human-derived Integrin alpha V beta 6 protein expressed by HEK293 with C-His labeled tag Integrin alpha V beta 6 Protein Human (HEK293 His) has molecular weight of 130 95 KDa respectively
Medchemexpress LLC Mac glucuronide linker-1 | 2222981-71-5 | MFCD32689543 | 96.4% | 897.90 | C42H47N3O17S | 25 MG
MAC glucuronide linker-1 is a cleavable antibody-drug conjugate (ADC) linker intended for research use, designed to release payloads through glucuronide cleavage under target conditions.
- Cleavable glucuronide-based linker for antibody-drug conjugates.
- Intended for research use only.
- CAS number 2222981-71-5.
- Purity 96.36%.
- Molecular weight 897.90.
- Chemical formula C42H47N3O17S.
- Appearance white to off-white solid.
- Storage: store under nitrogen; in solvent, -80°C for 6 months and -20°C for 1 month.
Apexbio Technology LLC Heparin(Synonyms: Heparin Sodium, Unfractionated Heparin, Sodium Heparin, Heparinic Acid, Liquaemin, Calciparine), 100mg, CAS: 9005-49-6.
Heparin (CAS 9005-49-6) is a highly sulfated glycosaminoglycan known primarily for its anticoagulant properties In biological systems it is stored in granules within specific animal tissues and cells potentially serving defensive roles against pathogens In vitro studies demonstrate that Heparin dose-dependently suppresses granulocyte aggregation and degranulation triggered by FMLP or serum-activated zymosan and specifically blocks FMLP-induced superoxide anion production Additionally in rat models Heparin treatment reduces both the binding affinity and density of angiotensin II receptors on adrenal cells resulting in decreased angiotensin II-stimulated aldosterone secretion Heparin is extensively applied in biomedical research to investigate granulocyte-mediated inflammation and renin-angiotensin system signaling
Apexbio Technology LLC D-AP5(Synonyms: D-2-Amino-5-phosphonopentanoic acid, D-APV, D(-)-2-Amino-5-phosphonovaleric acid), 10mg, CAS: 79055-68-8.
D-AP5 (CAS 79055-68-8) is a selective antagonist of the NMDA receptor It competitively inhibits glutamate binding at the NMDA receptor site exhibiting an affinity constant (Kd) of approximately 1 4 M In animal research administration of D-AP5 leads to impairment in spatial learning tasks specifically causing deficits in sensorimotor function and spatial memory performance Due to its targeted action on NMDA receptors D-AP5 serves as an important pharmacological tool for studying glutamate-related synaptic plasticity learning and memory mechanisms
Medchemexpress LLC Integrin alpha 8 bet 10ug
Integrin -8/ -1 coordinates the recruitment of mesenchymal cells during renal organogenesis and recognizes RGD sequences in ligands such as TNC FN1 SPP1 TGFB1 TGFB3 and VTN It plays a role in multiple cellular interactions critical for organogenesis including NPNT as a functional ligand in nephrogenesis Integrin alpha 8 beta 1 Protein Human (HEK293 His) is a recombinant protein dimer complex containing human-derived Integrin alpha 8 beta 1 protein expressed by HEK293 with C-His labeled tag Integrin alpha 8 beta 1 Protein Human (HEK293 His) has molecular weight of 120-140 kDa 100-120 kDa respectively
Medchemexpress LLC 2H-1-benzopyran-2-one, 7-(beta-D-glucopyranosyloxy)-4-methyl- | 18997-57-4 | MFCD00063694 | 99.9% | 338.31 g/mol | C16H18O8 | 10MM 1ML
4-Methylumbelliferyl β-D-glucopyranoside is a coumarin-based fluorogenic substrate used to measure β-glucosidase and related enzyme activities. Enzymatic hydrolysis releases the fluorescent 4-methylumbelliferone (4-MU), which emits near 445-454 nm; excitation is pH-dependent. The product is supplied as a 10 mM solution in DMSO (1 mL) and is suitable for fluorescence-based biochemical assays.
Medchemexpress LLC 4-Methylumbelliferyl 100mg | 18323-58-5 | 440.61 g·mol^-1 | C28H40O4 | 100 MG
4-Methylumbelliferyl oleate is a fluorogenic substrate for acid and alkaline lipases. Upon enzymatic hydrolysis, it liberates 4-methylumbelliferone (4-MU), enabling sensitive fluorometric detection and kinetic assays (Ex/Em 320/450 nm).
- Provides a fluorogenic readout upon lipase-catalyzed hydrolysis.
- Releases 4-methylumbelliferone with Ex/Em 320/450 nm for sensitive detection.
- High chemical purity suitable for enzymatic assays.
- Stable when stored at -20°C and protected from light; solvent stability guidelines available.
- Available in multiple pack sizes to support assay development and scale-up.
Medchemexpress LLC Integrin alpha X bet 100ug
Integrin -X/ -2 is a receptor for fibrinogen that recognizes GPR sequences It plays a key role in inflammatory responses particularly in monocyte adhesion and chemotaxis Integrin alpha X beta 2 Protein Human (HEK293 His) is a recombinant protein dimer complex containing human-derived Integrin alpha X beta 2 protein expressed by HEK293 with C-His labeled tag Integrin alpha X beta 2 Protein Human (HEK293 His) has molecular weight of 130-150 kDa (ITGAX) 85-96 kDa (ITGB2) respectively
Apexbio Technology LLC Beta-Lapachone 4707-32-8 10mg
Beta-Lapachone (CAS 4707-32-8) is a small molecule inhibitor of DNA topoisomerase I In DNA unwinding assays beta-Lapachone suppresses topoisomerase I-mediated DNA relaxation at concentrations as low as 1 M without inhibiting topoisomerase II or inducing topoisomerase I-dependent DNA cleavage It exhibits broad cytotoxicity against human cancer cell lines such as AD2780s HT-29 DLD G480 and MCF-7 with IC50 values ranging from 2 to 5 M The compound induces cell death through cytochrome c release triggering both apoptosis and necrosis and affects cell cycle progression causing S-phase and G2/M arrest in different carcinoma cell models Beta-Lapachone is widely utilized in studies investigating topoisomerase I inhibition cancer cell cytotoxicity and cell cycle regulation
Medchemexpress LLC Beta-sitosterol | 83-46-5 | MFCD00003631 | 98.0% | 414.71 g·mol⁻¹ | C29H50O | 10 MG
Beta-sitosterol is a plant-derived phytosterol used as a reference standard and research reagent for studies of cell signaling, inflammation, oxidative stress, and antitumor activity. It is supplied in small quantities suitable for laboratory assays and analytical work.
- Used as a reference standard in biochemical and analytical assays.
- Relevant for studies of inflammation, oxidative stress, and cell signaling.
- High purity provides reproducible experimental results.
- Available in small package sizes suitable for bench-scale experiments.
![Medchemexpress LLC 4-methyl-5-[2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]-1,3-thiazol-2-amine | 693228-63-6 | MFCD14155805 | 99.1% | 368.46 g·mol⁻¹ | C18H20N6OS | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000241055.png-250.jpg)
Medchemexpress LLC 4-methyl-5-[2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]-1,3-thiazol-2-amine | 693228-63-6 | MFCD14155805 | 99.1% | 368.46 g·mol⁻¹ | C18H20N6OS | 25 MG
CYC-116 is a small-molecule inhibitor of Aurora A and Aurora B kinases with low-nanomolar inhibitory potency. It is used as a research reagent to investigate mitotic signaling and cell-cycle regulation and is supplied as a purified solid for in vitro studies.
- Potent dual Aurora A and B inhibitor with Ki ≈8-9 nM.
- Suitable for studying mitotic signaling and cell-cycle regulation in vitro.
- High purity (>99.0%) for reliable experimental results.
- Chemical formula C18H20N6OS; molecular weight 368.46 g·mol⁻¹.
- Available in multiple small-quantity pack sizes for laboratory use.
Selleck Chemical LLC D-Glucuronic acid
D-Glucuronic acid (D-Glucopyranuronic Acid) is a key intermediate metabolite of the uronic acid pathway and may plays a role in the detoxification of certain drugs
![Medchemexpress LLC [1-(3,4-dichlorophenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl](3,3-difluoro-1-azetidinyl)-methanone | 2410550-31-9 | 99.8% | C17H11Cl2F2N3O | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000260266.png-250.jpg)
Medchemexpress LLC [1-(3,4-dichlorophenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl](3,3-difluoro-1-azetidinyl)-methanone | 2410550-31-9 | 99.8% | C17H11Cl2F2N3O | 10MG
KVA-D-88 is a research-grade small-molecule inhibitor selective for phosphodiesterase 4B (PDE4B). It is brain-penetrant and has been used in preclinical studies to probe PDE4-mediated signaling and cocaine-related behavioral effects.
- Selective PDE4B inhibition; reported IC50 140 nM (PDE4D IC50 880 nM).
- Brain-penetrant small molecule suitable for in vivo studies.
- High chemical purity (>99.8%).
- Solid, white to off-white powder form.
- Stable when stored at recommended temperatures for long-term use.
- Supplied for research use only; not for human or veterinary use.
Selleck Chemical LLC Heparin sodium S1346-1g
Heparin sodium a sulfated polysaccharide belonging to the family of glycosaminoglycans has numerous important biological activities associated with its interaction with diverse proteins Heparin is used as an anticoagulant primarily through its interaction with AT III by enhancing AT-IIImediated inhibition of blood coagulation factors including thrombin and factor Xa Heparin prevents the induction of autophagy