Sugar acids and derivatives
Medchemexpress LLC UDP-glucuronic acid trisodium | 63700-19-6 | 25 MG
UDP-glucuronic acid trisodium (Uridine-5'-diphosphoglucuronic acid trisodium salt) is a critical precursor for essential glycoconjugates across biological kingdoms, including mammalian glycosaminoglycans, plant cell wall polysaccharides, and bacterial capsule glycoglycerolipids.
- Promotes the migration of liver cancer cells (Huh7, SK-Hep1, and SNU449) at concentrations of 0.5-1 mM over 24 hours.
- Induces the EMT process.
- Decreased E-cadherin levels and increased vimentin levels in Huh7 and SNU449 cells at 0.5 mM over 24 hours.
Apexbio Technology LLC β-Interleukin II (44-56) 25mg
beta-Interleukin II 44-56 is a synthetic peptide fragment derived from interleukin-2 (IL-2) It is designed to serve as a functional IL-2 derivative peptide thereby facilitating studies on immune system modulation and T-cell regulation beta-Interleukin II 44-56 exerts its biological activity by providing a representative segment of IL-2 which supports investigation of T-cell activity regulatory T-cell mechanisms and immunological signaling pathways in cellular and molecular immunology research Based on these pharmacological properties beta-Interleukin II 44-56 holds research potential in studies of immune regulation T-cell biology and immune-related disease mechanisms
![eMolecules 3-AZABICYCLO[3.1.0]HEXANE-6-CARBOXYLIC ACID HCL | 1260794-12-4 | MFCD11109557 | 1g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502181355.JPG-250.jpg)
eMolecules 3-AZABICYCLO[3.1.0]HEXANE-6-CARBOXYLIC ACID HCL | 1260794-12-4 | MFCD11109557 | 1g
AstaTech | 3-AZABICYCLO[3.1.0]HEXANE-6-CARBOXYLIC ACID HCL | 1g | 233629139 | 60015 | 95.000 | 1260794-12-4 | MFCD11109557 | 163.600 | C6H10ClNO2
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eMolecules Building Block Tool
Medchemexpress LLC Heparin sodium salt | 9041-08-1 | 15 kDa (for a specific form) | 25MG
Heparin sodium salt (Sodium heparin) is an anticoagulant that reversibly binds to antithrombin III (ATIII), significantly accelerating the rate at which ATIII inactivates coagulation enzymes thrombin factor IIa and factor Xa. It also notably inhibits exosome-cell interactions. Heparin is a complex linear polymer composed of chains of varying lengths and sequences.
- Acts as a potent anticoagulant.
- Enhances antithrombin-mediated inhibition of blood coagulation factors.
- Interacts with FGF-2 and FGFR-1, stabilizing FGF-FGFR binding.
- Promotes FGFR dimerization.
Medchemexpress LLC Heparin sodium salt (MW 15kDa) | 9041-08-1 | 15000 (Average) | 5 G
Heparin sodium salt (MW 15kDa) is a polymer of Heparin with a molecular weight of 15kDa. It functions as an anticoagulant by reversibly binding to antithrombin III (ATIII), which significantly increases the rate at which ATIII inactivates coagulation enzymes thrombin factor IIa and factor Xa. This product has shown angiogenic response in late Chorioallantoic Membrane (CAM) assay. It is suitable for laboratory centrifugation and storage.
- Acts as an anticoagulant
- Binds reversibly to antithrombin III (ATIII)
- Accelerates inactivation of coagulation enzymes
- Used in various biological activities targeting thrombin and factor Xa
- Shows angiogenic response in CAM assay
Medchemexpress LLC 2,4-D sodium (Standard) | 2702-72-9 | 97% | 243.02 | 100 MG
2,4-D sodium (Standard) is an analytical standard intended for research and analytical applications. It functions as a selective herbicide, controlling broad-leaved weeds. The compound induces apoptosis and inhibits DNA and protein synthesis, thereby preventing normal plant growth and development. It serves as a reference standard for assay.
- Intended for research and analytical applications.
- Selective herbicide for broad-leaved weeds.
- Induces apoptosis.
- Inhibits DNA and protein synthesis.
- Prevents normal plant growth and development.
- Used in qualitative, quantitative, and methodological research experiments.
- Suitable for HPLC, GC, and MS applications.
Medchemexpress LLC SN-38 glucuronide | 121080-63-5 | 99.49% | 568.53 | 50 MG
SN-38 glucuronide is an inactive metabolite of the anticancer active molecule Irinotecan and has toxic effects on the gastrointestinal tract. Irinotecan is a topoisomerase I inhibitor used for researching colon and rectal cancer. SN38-G is the glucuronidated metabolite of SN38. Cells with the ability to metabolize SN38 to SN38-G are more resistant to extracellular SN38 than cells lacking this capability. SN-38 glucuronide can also serve as a substrate for gut microbial β-glucuronidase enzymes, which remove the glucuronic acid moiety to reactivate SN-38, thereby increasing its toxic effects on the gut.
- For research use only.
Medchemexpress LLC SN-38 glucuronide (SN-38G) | 121080-63-5 | 99.5% | 568.53 | 10 MG
SN-38 glucuronide is an inactive metabolite of the anticancer active molecule Irinotecan and has toxic effects on the gastrointestinal tract. Irinotecan is a topoisomerase I inhibitor which can be used for researching colon and rectal cancer.
- Inactive metabolite of the anticancer active molecule irinotecan.
- Has toxic effects on the gastrointestinal tract.
- Cells capable of metabolizing SN38 to SN38-G show increased resistance to extracellular SN38.
- Can serve as a substrate for gut microbial β-glucuronidase enzymes, which reactivate SN-38 in the intestine, leading to increased toxic effects on the gut.
Medchemexpress LLC Integrin alpha 8 bet 500ug
Integrin -8/ -1 coordinates the recruitment of mesenchymal cells during renal organogenesis and recognizes RGD sequences in ligands such as TNC FN1 SPP1 TGFB1 TGFB3 and VTN It plays a role in multiple cellular interactions critical for organogenesis including NPNT as a functional ligand in nephrogenesis Integrin alpha 8 beta 1 Protein Human (HEK293 Flag His) is a recombinant protein dimer complex containing human-derived Integrin alpha 8 beta 1 protein expressed by HEK293 with C-10 His C-Flag labeled tag Integrin alpha 8 beta 1 Protein Human (HEK293 Flag His) has molecular weight of 85-140 kDa